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11.发明申请公开(公告)号：US20140172063A1
公开(公告)日：2014-06-19
申请号：US14017548
申请日：2013-09-04
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： Stephen Dirk Pacetti
CPC classification number: A61L31/16 , A61F2/82 , A61F2/91 , A61F2/915 , A61F2/958 , A61F2002/91516 , A61F2002/91533 , A61F2002/91575 , A61F2002/9583 , A61F2220/005 , A61F2220/0058 , A61F2230/0013 , A61F2250/0067 , Y10T29/49826
Abstract: A drug-eluting stent delivery system for the treatment of edge restenosis in a blood vessel. The drug-eluting stent delivery system has a balloon disposed about at least a portion of a catheter, the balloon having a first end and a second end and a working length therebetween, the first end and the second end each including a tapered portion, each tapered portion being attached to the catheter, the balloon being inflatable from a collapsed configuration to an inflated configuration. A drug-eluting stent contacts a wall of the blood vessel to maintain the patency of the vessel. The drug-eluting stent has a first end and a second end, the first end and the second end each including a tapered portion, wherein the drug-eluting stent is disposed over the balloon such that at least a portion of the first end and the second end of the balloon are covered by the tapered drug-eluting stent. A method for making the same is also disclosed herein.
Abstract translation: 用于治疗血管中边缘再狭窄的药物洗脱支架递送系统。 药物洗脱支架递送系统具有围绕导管的至少一部分设置的球囊，所述球囊具有第一端和第二端以及其间的工作长度，第一端和第二端各自包括锥形部分，每个 锥形部分附接到导管，气囊可从折叠构型充气到膨胀构型。 药物洗脱支架接触血管的壁以维持血管的通畅。 药物洗脱支架具有第一端和第二端，第一端和第二端各自包括锥形部分，其中药物洗脱支架设置在气囊上方，使得第一端和第二端的至少一部分 气囊的第二端由锥形药物洗脱支架覆盖。 本文还公开了制备该方法的方法。
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12.发明授权Drug-eluting stent and delivery system with tapered stent in shoulder region 有权药物洗脱支架和带锥形支架的递送系统在肩部区域公开(公告)号：US08551152B2
公开(公告)日：2013-10-08
申请号：US13727327
申请日：2012-12-26
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Stephen Dirk Pacetti
IPC: A61F2/06
CPC classification number: A61L31/16 , A61F2/82 , A61F2/91 , A61F2/915 , A61F2/958 , A61F2002/91516 , A61F2002/91533 , A61F2002/91575 , A61F2002/9583 , A61F2220/005 , A61F2220/0058 , A61F2230/0013 , A61F2250/0067 , Y10T29/49826
Abstract: A drug-eluting stent delivery system for the treatment of edge restenosis in a blood vessel. The drug-eluting stent delivery system has a balloon disposed about at least a portion of a catheter, the balloon having a first end and a second end and a working length therebetween, the first end and the second end each including a tapered portion, each tapered portion being attached to the catheter, the balloon being inflatable from a collapsed configuration to an inflated configuration. A drug-eluting stent contacts a wall of the blood vessel to maintain the patency of the vessel. The drug-eluting stent has a first end and a second end, the first end and the second end each including a tapered portion, wherein the drug-eluting stent is disposed over the balloon such that at least a portion of the first end and the second end of the balloon are covered by the tapered drug-eluting stent. A method for making the same is also disclosed herein.
Abstract translation: 用于治疗血管中边缘再狭窄的药物洗脱支架递送系统。 药物洗脱支架递送系统具有围绕导管的至少一部分设置的球囊，所述球囊具有第一端和第二端以及其间的工作长度，第一端和第二端各自包括锥形部分，每个 锥形部分附接到导管，气囊可从折叠构型充气到膨胀构型。 药物洗脱支架接触血管的壁以维持血管的通畅。 药物洗脱支架具有第一端和第二端，第一端和第二端各自包括锥形部分，其中药物洗脱支架设置在气囊上方，使得第一端和第二端的至少一部分 气囊的第二端由锥形药物洗脱支架覆盖。 本文还公开了制备该方法的方法。
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公开(公告)号：US09468706B2
公开(公告)日：2016-10-18
申请号：US14664554
申请日：2015-03-20
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Thierry Glauser , Stephen Dirk Pacetti , Syed Faiyaz Ahmed Hossainy , Ni Ding
CPC classification number: A61L31/10 , A61L27/34 , A61L31/148 , A61L31/16 , A61L33/0011 , A61L33/08 , A61L2300/40 , A61L2300/42 , A61L2300/604 , A61L2300/606 , A61L2400/18 , C08L33/14
Abstract: A polymer comprising phospholipid moieties and a biocompatible polymer backbone, a composition comprising the polymer and optionally a bioactive agent, an implantable devices such as a drug eluting stent comprising thereon a coating comprising the polymer and optionally a bioactive agent, and a method of using the device for the treatment of a disorder in a human being are provided.
Abstract translation: 包含磷脂部分和生物相容性聚合物骨架的聚合物，包含聚合物和任选的生物活性剂的组合物，可植入装置，例如药物洗脱支架，其上包含包含聚合物和任选的生物活性剂的涂层，以及使用 提供了用于治疗人类疾病的装置。
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公开(公告)号：US20140322294A1
公开(公告)日：2014-10-30
申请号：US14323816
申请日：2014-07-03
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Stephen Dirk Pacetti
CPC classification number: A61L31/10 , A61L27/00 , A61L27/14 , A61L27/34 , A61L31/08 , A61L31/148 , A61L2420/00 , A61L2420/02
Abstract: Biodegradable coatings for implantable medical devices are disclosed.
Abstract translation: 公开了用于可植入医疗装置的可生物降解涂层。
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15.发明授权Drug-eluting stent and delivery system with tapered stent in shoulder region 有权药物洗脱支架和带锥形支架的递送系统在肩部区域公开(公告)号：US08852260B2
公开(公告)日：2014-10-07
申请号：US14017548
申请日：2013-09-04
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Stephen Dirk Pacetti
CPC classification number: A61L31/16 , A61F2/82 , A61F2/91 , A61F2/915 , A61F2/958 , A61F2002/91516 , A61F2002/91533 , A61F2002/91575 , A61F2002/9583 , A61F2220/005 , A61F2220/0058 , A61F2230/0013 , A61F2250/0067 , Y10T29/49826
Abstract: A drug-eluting stent delivery system for the treatment of edge restenosis in a blood vessel. The drug-eluting stent delivery system has a balloon disposed about at least a portion of a catheter, the balloon having a first end and a second end and a working length therebetween, the first end and the second end each including a tapered portion, each tapered portion being attached to the catheter, the balloon being inflatable from a collapsed configuration to an inflated configuration. A drug-eluting stent contacts a wall of the blood vessel to maintain the patency of the vessel. The drug-eluting stent has a first end and a second end, the first end and the second end each including a tapered portion, wherein the drug-eluting stent is disposed over the balloon such that at least a portion of the first end and the second end of the balloon are covered by the tapered drug-eluting stent. A method for making the same is also disclosed herein.
Abstract translation: 用于治疗血管中边缘再狭窄的药物洗脱支架递送系统。 药物洗脱支架递送系统具有围绕导管的至少一部分设置的球囊，所述球囊具有第一端和第二端以及其间的工作长度，第一端和第二端各自包括锥形部分，每个 锥形部分附接到导管，气囊可从折叠构型充气到膨胀构型。 药物洗脱支架接触血管的壁以维持血管的通畅。 药物洗脱支架具有第一端和第二端，第一端和第二端各自包括锥形部分，其中药物洗脱支架设置在气囊上方，使得第一端和第二端的至少一部分 气囊的第二端由锥形药物洗脱支架覆盖。 本文还公开了制备该方法的方法。
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Patent Agency Ranking
16.发明授权公开(公告)号：US08722826B2
公开(公告)日：2014-05-13
申请号：US13863261
申请日：2013-04-15
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Stephen Dirk Pacetti , Wouter Erik Roorda
IPC: C08F30/02 , C08F118/02 , C08F26/00 , C08F18/00 , C08F220/10 , A61F2/00
CPC classification number: C08F230/02 , A61F2/91 , A61L27/34 , A61L31/10 , C08F2220/1825 , C08F2220/282 , C09D133/14 , C08L33/14 , C08F220/36
Abstract: Biocompatible terpolymers are manufactured to include a zwitterionic monomer, an alkoxy acrylate monomer, and a hydrophobic monomer.
Abstract translation: 制备生物相容性三元共聚物以包括两性离子单体，烷氧基丙烯酸酯单体和疏水性单体。
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17.发明申请ZWITTERIONIC TERPOLYMERS, METHOD OF MAKING AND USE ON MEDICAL DEVICES 失效ZWITTERICIC TERPOLYMERS，METHOD OF MAKING AND USE ON MEDICAL DEVICES公开(公告)号：US20130296513A1
公开(公告)日：2013-11-07
申请号：US13863261
申请日：2013-04-15
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Stephen Dirk Pacetti , Wouter Erik Roorda
IPC: C08F230/02
CPC classification number: C08F230/02 , A61F2/91 , A61L27/34 , A61L31/10 , C08F2220/1825 , C08F2220/282 , C09D133/14 , C08L33/14 , C08F220/36
Abstract: Biocompatible terpolymers are manufactured to include a zwitterionic monomer, an alkoxy acrylate monomer, and a hydrophobic monomer.
Abstract translation: 制备生物相容性三元共聚物以包括两性离子单体，烷氧基丙烯酸酯单体和疏水性单体。
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18.发明申请公开(公告)号：US20150351942A1
公开(公告)日：2015-12-10
申请号：US14712647
申请日：2015-05-14
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed F.A. Hossainy , David C. Gale , Stephen Dirk Pacetti , Bin Huang
IPC: A61F2/86
CPC classification number: A61F2/86 , A61F2210/0076 , A61F2230/0069 , A61L31/10 , A61L31/129
Abstract: Stents fabricated from polymer composites toughened by a dispersed phase are disclosed.
Abstract translation: 公开了由分散相增韧的聚合物复合材料制成的支架。
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公开(公告)号：US09101697B2
公开(公告)日：2015-08-11
申请号：US14251489
申请日：2014-04-11
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed Faiyaz Ahmed Hossainy , Eugene Michal , Thierry Glauser , Connie Kwok , Stephen Dirk Pacetti
IPC: A61K31/44 , A61L31/10 , A61K31/727 , A61K31/728 , A61K31/785 , A61L31/16
CPC classification number: A61L31/10 , A61K31/727 , A61K31/728 , A61K31/785 , A61L31/16 , A61K2300/00 , C08L5/08 , C08L5/10
Abstract: Hyaluronic acid (HA) conjugates or crosslinked HAs compositions for coating an implantable device are provided. The implantable device can be used for treating a disorder such as atherosclerosis, thrombosis, restenosis, high cholesterol, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, and combinations thereof.
Abstract translation: 提供了用于涂覆可植入装置的透明质酸（HA）缀合物或交联的HA组合物。 可植入装置可用于治疗动脉粥样硬化，血栓形成，再狭窄，高胆固醇，出血，血管解剖或穿孔，血管动脉瘤，易损斑块，慢性完全闭塞，跛行，静脉和人造移植物的吻合增殖等障碍，胆管 梗阻，输尿管阻塞，肿瘤阻塞及其组合。
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公开(公告)号：US08865189B2
公开(公告)日：2014-10-21
申请号：US13731875
申请日：2012-12-31
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Lothar Walter Kleiner , Jessica Reneé DesNoyer , Stephen Dirk Pacetti , Syed Faiyaz Ahmed Hossainy , O. Mikael Trollsas , Michael Huy Ngo
CPC classification number: A61L27/34 , A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2420/02
Abstract: Implantable medical devices including a coating having a bioactive agent and a poly(ester amide) polymer. Methods of forming these coatings are also described.
Abstract translation: 可植入医疗装置，包括具有生物活性剂和聚（酯酰胺）聚合物的涂层。 还描述了形成这些涂层的方法。
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