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公开(公告)号：US12109335B2
公开(公告)日：2024-10-08
申请号：US16811636
申请日：2020-03-06
IPC分类号： A61K9/16 , A61B5/00 , A61B8/00 , A61B8/12 , A61L31/02 , A61L31/06 , A61L31/12 , A61L31/14 , C08G77/00 , C08L83/04 , G01S15/89 , G10K11/30
CPC分类号： A61L31/129 , A61B5/0095 , A61B8/12 , A61B8/4444 , A61L31/028 , A61L31/06 , A61L31/128 , A61L31/14 , C08G77/70 , C08L83/04 , G01S15/8906 , G10K11/30 , C08L2205/025 , C08L2205/03
摘要： A composition for an acoustic wave probe, containing the following ingredients (A) to (D): (A) a linear polysiloxane having a vinyl group; (B) a linear polysiloxane having two or more Si—H groups in a molecular chain; (C) a polysiloxane resin; and (D) surface-treated silica particles having an average primary particle diameter more than 16 nm and less than 100 nm, as well as, a silicone resin for an acoustic wave probe, an acoustic wave probe, an ultrasound probe, an acoustic wave measurement apparatus, an ultrasound diagnostic apparatus, a photoacoustic wave measurement apparatus, and an ultrasound endoscope, using the composition for an acoustic wave probe.
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2.发明公开公开(公告)号：US20240245836A1
公开(公告)日：2024-07-25
申请号：US18595593
申请日：2024-03-05
申请人： Dimension Inx Corp
发明人： Adam E. Jakus
IPC分类号： A61L31/14 , A61L31/12 , B29C64/112 , B33Y10/00 , B33Y40/10 , B33Y40/20 , B33Y70/10 , B33Y80/00 , B82Y5/00
CPC分类号： A61L31/145 , A61L31/129 , A61L31/146 , B29C64/112 , B33Y10/00 , B33Y40/10 , B33Y40/20 , B33Y70/10 , B33Y80/00 , A61L2400/12 , B82Y5/00
摘要： Disclosed are Self-Gelling materials and structures or materials or structures having one or more self-gelling components that overcome existing gel limitations due to hydrogel localization for medical applications by providing, for example, 1) microstructurally, or physically, anchored characteristics to help localize the gel, and the overall printed, or otherwise formed structure, giving structural form to the gel that allows the gel to be localized within the body, and even sutured in place, and mitigates gel migration and extends its residence time; 2) to provide an underlying 3D printed structure to help contain and support the gel after implantation; and more. Self-Gelling 3D printed structures may be further processed via milling to yield deconstructed scaffold micro-granules, with the composition and nano-/micro-structure of the original larger structure. Deconstructed scaffold micro-granules may be hydrated to form a micro-granule embedded gel network that can be injected, giving form to injectable gels.
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公开(公告)号：US20240018707A1
公开(公告)日：2024-01-18
申请号：US18219246
申请日：2023-07-07
申请人： POLY-MED, INC.
CPC分类号： D04H1/728 , A61L31/14 , A61L31/129 , A61L31/148 , A61L31/06 , D04H1/43835 , A61F2/0063 , A61L2400/12 , A61F2210/0004
摘要： Thermally stable absorbable fiber populations, i.e. fiber populations that do not undergo thermally induced crystallization, can be intermixed to yield a stabilizing effect without altering morphological properties of a first fiber system. By addition of a stabilizing fiber population one may minimize thermally induced shrinkage and maintain physical properties of electrospun materials in the as-formed state. In one particular abstract, medical barrier materials may be formed from the electrospun materials to provide improved medical barriers for treatments.
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公开(公告)号：US11739452B2
公开(公告)日：2023-08-29
申请号：US15115650
申请日：2015-01-30
申请人： POLY-MED, INC.
CPC分类号： D04H1/728 , A61F2/0063 , A61L31/06 , A61L31/129 , A61L31/14 , A61L31/148 , D04H1/43835 , A61F2210/0004 , A61L2400/12 , A61L31/06 , C08L67/04 , A61L31/129 , C08L67/04 , A61L31/129 , C08L67/02
摘要： Thermally stable absorbable fiber populations, i.e. fiber populations that do not undergo thermally induced crystallization, can be intermixed to yield a stabilizing effect without altering morphological properties of a first fiber system. By addition of a stabilizing fiber population one may minimize thermally induced shrinkage and maintain physical properties of electrospun materials in the as-formed state. In one particular abstract, medical barrier materials may be formed from the electrospun materials to provide improved medical barriers for treatments.
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公开(公告)号：US20190218334A1
公开(公告)日：2019-07-18
申请号：US16248498
申请日：2019-01-15
CPC分类号： C08G18/6208 , A61L27/16 , A61L29/041 , A61L31/048 , A61L31/129 , A61L31/143 , C08G18/12 , C08G18/2865 , C08G18/4063 , C08G18/4808 , C08G18/4854 , C08G18/6204 , C08G18/7671 , C08G18/833 , C08G18/3206 , C08L53/00
摘要： A polymeric material includes a polyisobutylene-polyurethane block copolymer. The polyisobutylene-polyurethane block copolymer includes soft segments, hard segments, and end groups. The soft segments include a polyisobutylene diol residue. The hard segments include a diisocyanate residue. The end groups are bonded by urea bonds to a portion of the diisocyanate residue. The end groups include a residue of a mono-functional amine.
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公开(公告)号：US20180296735A1
公开(公告)日：2018-10-18
申请号：US16014184
申请日：2018-06-21
申请人： Poly-Med, Inc.
发明人： Shalaby W. Shalaby
CPC分类号： A61L31/129 , A61B17/42 , A61B2090/0816 , A61F2/0063 , A61L27/48 , A61L27/58 , A61L31/148 , A61L2430/22 , A61L2430/38 , D01D5/003
摘要： Absorbable barrier composites are designed for modulated gas and water permeability depending on clinical use and are formed of at least two physicochemically distinct components, one of which is a film adjoined to a knitted mesh and/or electrostatically spun, non-woven fabric. Depending on the physicochemical properties of the barrier composite, it can be used in neurological and urinogenital surgical procedures as well as tissue engineering and/or as physical barriers to prevent adhesion formation following several types of surgical procedures.
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公开(公告)号：US20170216496A1
公开(公告)日：2017-08-03
申请号：US15327234
申请日：2015-07-17
申请人： ETHICON, INC.
发明人： Daniel J. Smith , Christophe Vailhe
CPC分类号： A61L31/129 , A61L24/001 , A61L24/0031 , A61L24/0042 , A61L24/0094 , A61L31/14 , A61L31/145 , A61L31/148 , A61L2300/404 , A61L2400/06 , C08L1/00 , C08L1/04 , C08L1/26
摘要： Combination cellulose materials and methods of making and using these materials. The combination material includes a first cellulosic material and a second cellulosic material.
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公开(公告)号：US09717610B2
公开(公告)日：2017-08-01
申请号：US14856427
申请日：2015-09-16
发明人： Bin Huang , David C. Gale
IPC分类号： B29C47/00 , B29C47/06 , A61F2/91 , A61F2/915 , B29C53/58 , B29C59/02 , B29C53/56 , B23K26/50 , A61F2/90 , A61L31/12 , A61F2/04 , A61F2/06 , B23K26/402 , B29C45/00 , B29C43/02 , D03D3/02 , B29C47/10 , A61F2/07 , B23K103/00 , B29K101/00 , B29K105/12 , B29L23/00 , B29L31/00
CPC分类号： A61F2/915 , A61F2/04 , A61F2/06 , A61F2/90 , A61F2/91 , A61F2002/072 , A61F2002/91508 , A61F2002/91575 , A61F2210/0004 , A61F2210/0009 , A61F2210/0076 , A61F2220/005 , A61F2230/0013 , A61F2250/0098 , A61L31/129 , B23K26/402 , B23K26/50 , B23K2103/42 , B23K2103/50 , B29C43/02 , B29C45/0001 , B29C45/0005 , B29C45/0055 , B29C47/0004 , B29C47/0023 , B29C47/0026 , B29C47/0066 , B29C47/06 , B29C47/1045 , B29C53/566 , B29C53/583 , B29C59/02 , B29C59/021 , B29C2043/028 , B29K2101/00 , B29K2105/12 , B29K2267/043 , B29K2995/0056 , B29K2995/006 , B29L2023/003 , B29L2031/7546 , D03D3/02
摘要： Polymeric composite stents reinforced with fibers for implantation into a bodily lumen are disclosed.
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公开(公告)号：US09616155B2
公开(公告)日：2017-04-11
申请号：US12484274
申请日：2009-06-15
CPC分类号： A61L31/16 , A61L31/048 , A61L31/06 , A61L31/129 , A61L2300/21 , A61L2300/412 , A61L2300/414 , A61L2300/42 , A61L2430/06 , A61L2430/10 , C08L23/12
摘要： Fixation devices for tissue repair, for example sutures, surgical arrows, staples, darts, bolts, screws, buttons, anchors, nails, rivets, or barbed devices comprise at least one of angiogenic material; angiogenic precursor material which is capable of breaking down in vivo to form angiogenic material; or tissue-engineered material, which tissue-engineered material is capable of producing angiogenic material. In a preferred form, the material is incorporated into a polymer matrix having predetermined hydrophobicity to allow controlled release of angiogenic materials such as butyric or hydroxybutyric acid or salts thereof. Polymer matrix compositions comprising angiogenic materials and methods for tissue repair are also provided.
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公开(公告)号：US09510935B2
公开(公告)日：2016-12-06
申请号：US13675730
申请日：2012-11-13
发明人： Larry J Kovach , Rachel Radspinner
IPC分类号： A61F2/07 , C09D127/18 , B32B38/18 , A61F2/82 , F21V33/00 , A61L31/10 , A61L31/12 , A61L31/14 , A61L31/04
CPC分类号： A61L31/048 , A61F2/07 , A61F2/82 , A61F2002/075 , A61F2240/002 , A61L31/10 , A61L31/129 , A61L31/146 , B29C65/02 , B29C66/545 , B29K2055/00 , B29K2105/04 , B29K2105/08 , B29L2009/00 , B29L2031/753 , B32B1/08 , B32B5/10 , B32B27/322 , B32B37/06 , B32B38/1866 , B32B2305/02 , B32B2355/00 , B32B2535/00 , C09D127/18 , F21V33/0076 , Y10T156/1075 , Y10T428/24802 , Y10T428/2481 , C08L27/12 , C08L27/18
摘要： Articles comprising an expanded polytetrafluoroethylene membrane having serpentine fibrils and having a discontinuous coating of a fluoropolymer thereon are provided. The fluoropolymer may be located at least partially in the pores of the expanded fluoropolymer membrane. In exemplary embodiments, the fluoropolymer is fluorinated ethylene propylene. The application of a tensile force at least partially straightens the serpentine fibrils, thereby elongating the article. The expanded polytetrafluoroethylene membrane may include a microstructure of substantially only fibrils. The articles can be elongated to a predetermined point at which further elongation is inhibited by a dramatic increase in stiffness. In one embodiment, the articles are used to form a covered stent device that requires little force to distend in the radial direction to a first diameter but is highly resistant to further distension to a second diameter (stop point). A large increase in diameter can advantageously be achieved prior to reaching the stop point.
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