公开(公告)号：US20150310640A1

公开(公告)日：2015-10-29

申请号：US14261623

申请日：2014-04-25

Applicant: General Electric Company

Inventor： Christopher Judson Hardy ,  Luca Marinelli ,  Marion Irene Menzel ,  Ek Tsoon Tan ,  Jonathan Immanuel Sperl

IPC: G06T11/00 ,  G06T7/00

CPC classification number: G06T11/006 ,  G01R33/4826 ,  G01R33/5611 ,  G01R33/56341 ,  G06T7/0012 ,  G06T2207/10088 ,  G06T2207/20056

Abstract: A method of compressed sensing for multi-shell magnetic resonance imaging includes obtaining magnetic resonance imaging data, the data being sampled along multi-shell spherical coordinates, the spherical coordinates coincident with a plurality of spokes that converge at an origin, constructing a symmetric shell for each respective sampled multi-shell to create a combined set of data, performing a three-dimensional Fourier transform on the combined set of data to reconstruct an image, and de-noising the reconstructed image by iteratively applying a sparsifying transform on non-sampled data points of neighboring shells. The method can also include randomly under-sampling the imaging data to create missing data points. A system configured to implement the method and a non-transitory computer readable medium are also disclosed.

Abstract translation: 一种用于多壳磁共振成像的压缩感测方法包括：获得磁共振成像数据，所述数据沿着多壳球面坐标进行采样，所述球面坐标与在原点收敛的多个辐条重合，构成对称壳体 每个相应的采样多壳以产生一组组合数据，对该组合数据进行三维傅里叶变换以重构图像，并通过对非采样数据迭代地应用稀疏变换来对重构图像进行去噪 相邻炮弹点。 该方法还可以包括随机对取样数据进行低采样以创建丢失的数据点。 还公开了一种被配置为实现该方法的系统和一种非暂时计算机可读介质。

公开(公告)号：US20140275962A1

公开(公告)日：2014-09-18

申请号：US13797395

申请日：2013-03-12

Applicant: GENERAL ELECTRIC COMPANY

Inventor： Thomas Kwok-Fah Foo ,  Lowell Scott Smith ,  Kai Erik Thomenius ,  Sandeep Narendra Gupta ,  Luca Marinelli ,  Kedar Anil Patwardhan ,  Dominic Michael Graziani

IPC: A61N2/00

CPC classification number: A61N2/002 ,  A61B5/0035 ,  H05K999/99

Abstract: Methods and systems using magnetic resonance and ultrasound for tracking anatomical targets for radiation therapy guidance are provided. One system includes a patient transport configured to move a patient between and into a magnetic resonance (MR) system and a radiation therapy (RT) system and an ultrasound transducer coupled to the patient transport, wherein the ultrasound transducer is configured to acquire four-dimensional (4D) ultrasound images concurrently with one of an MR acquisition or an RT radiation therapy session. The system also includes a controller having a processor configured to use the 4D ultrasound images and MR images from the MR system to control at least one of a photon beam spatial distribution or intensity modulation generated by the RT system.

Abstract translation: 提供了使用磁共振和超声波跟踪放射治疗指导解剖靶标的方法和系统。 一种系统包括被配置为将患者移动到磁共振（MR）系统和辐射治疗（RT）系统之间的患者输送和耦合到患者输送的超声换能器，其中超声换能器被配置为获取四维 （4D）超声图像与MR采集或RT放射治疗会话之一同时进行。 该系统还包括具有处理器的控制器，其被配置为使用来自MR系统的4D超声图像和MR图像来控制RT系统产生的光子束空间分布或强度调制中的至少一个。

公开(公告)号：US09897678B2

公开(公告)日：2018-02-20

申请号：US13866820

申请日：2013-04-19

Applicant: General Electric Company

Inventor： Ek Tsoon Tan ,  Christopher Judson Hardy ,  Kevin Franklin King ,  Zachary William Slavens ,  Luca Marinelli ,  Robert Marc Lebel

IPC: G01V3/00 ,  G01R33/565 ,  G01R33/563

CPC classification number: G01R33/56581 ,  G01R33/56341 ,  G01R33/56572

Abstract: Systems and methods for correcting magnetic resonance (MR) data are provided. One method includes receiving the MR data and correcting errors present in the MR data due to non-uniformities in magnetic field gradients used to generate the diffusion weighted MR signals. The method also includes correcting errors present in the MR data due to concomitant gradient fields present in the magnetic field gradients by using one or more gradient terms. At least one of the gradient terms is corrected based on the correction of errors present in the MR data due to the non-uniformities in the magnetic field gradients.

公开(公告)号：US20170014645A1

公开(公告)日：2017-01-19

申请号：US15277198

申请日：2016-09-27

Applicant: GENERAL ELECTRIC COMPANY

Inventor： Thomas Kwok-Fah Foo ,  Lowell Scott Smith ,  Kai Erik Thomenius ,  Sandeep Narendra Gupta ,  Luca Marinelli ,  Kedar Anil Patwardhan ,  Dominic Michael Graziani

IPC: A61N5/10 ,  A61B5/113 ,  A61B5/00 ,  A61B5/055 ,  A61B8/08

Abstract: Methods and systems using magnetic resonance and ultrasound for tracking anatomical targets for radiation therapy guidance are provided. One system includes a patient transport configured to move a patient between and into a magnetic resonance (MR) system and a radiation therapy (RT) system. An ultrasound transducer is also provided that is hands-free and electronically steerable, securely attached to the patient, such that the ultrasound transducer is configured to acquire four-dimensional (4D) ultrasound images concurrently with one of an MR acquisition or an RT radiation therapy session. The system also includes a controller having a processor configured to use the 4D ultrasound images and MR images from the MR system to control at least one of a photon beam spatial distribution or intensity modulation generated by the RT system. The system determines the previously-acquired correct MR images that represent a specific motion state at some time, t, by a plurality of transformations that allow the representation of the position of fiducial markers in the corresponding ultrasound images to match that of a prior ultrasound acquisition.

Abstract translation: 提供了使用磁共振和超声波跟踪放射治疗指导解剖靶标的方法和系统。 一个系统包括被配置为将患者移动到磁共振（MR）系统和放射治疗（RT）系统之间）的患者输送。 还提供了一种超声换能器，其是免提的并且可电子操纵的，牢固地附接到患者，使得超声换能器被配置为与MR采集或RT放射治疗之一同时获取四维（4D）超声图像 会话 该系统还包括具有处理器的控制器，其被配置为使用来自MR系统的4D超声图像和MR图像来控制RT系统产生的光子束空间分布或强度调制中的至少一个。 该系统通过允许在对应的超声图像中的基准标记的位置的表示与先前的超声波获取相匹配的多个变换来确定在某时刻t表示特定运动状态的先前获得的正确MR图像 。

公开(公告)号：US20160334489A1

公开(公告)日：2016-11-17

申请号：US14711650

申请日：2015-05-13

Applicant: General Electric Company

Inventor： Jonathan Immanuel Sperl ,  Christopher Judson Hardy ,  Luca Marinelli ,  Marion Irene Menzel ,  Ek Tsoon Tan

IPC: G01R33/563 ,  G01R33/56 ,  G01R33/561 ,  G01R33/385

CPC classification number: G01R33/56341 ,  G01R33/5608

Abstract: A magnetic resonance imaging method includes generating spatially resolved fiber orientation distributions (FODs) from magnetic resonance signals acquired from a patient tissue using a plurality of diffusion encodings, each acquired magnetic resonance signal corresponding to one of the diffusion encodings and being representative of a three-dimensional distribution of displacement of magnetic spins of gyromagnetic nuclei present in each imaging voxel. Generating the spatially resolved FODs includes performing generalized spherical deconvolution using the acquired magnetic resonance signals and a modeled tissue response matrix (TRM) to reconstruct the spatially resolved FODs. The method also includes using the spatially resolved FODs to generate a representation of fibrous tissue within the patient tissue.

Abstract translation: 磁共振成像方法包括使用多个扩散编码从从患者组织获取的磁共振信号产生空间分辨纤维取向分布（FOD），每个获得的磁共振信号对应于一个扩散编码，并且代表三维 每个成像体素中存在的回旋磁核的磁自旋的位移的尺寸分布。 生成空间分辨的FOD包括使用获取的磁共振信号和建模的组织响应矩阵（TRM）来执行广义的球形去卷积以重构空间分辨的FOD。 该方法还包括使用空间分辨的FOD来产生患者组织内的纤维组织的表示。

公开(公告)号：US09149205B2

公开(公告)日：2015-10-06

申请号：US13852723

申请日：2013-03-28

Applicant: General Electric Company

Inventor： Ileana Hancu ,  Kenneth William Rohling ,  Luca Marinelli ,  Eric William Fiveland ,  Seung-Kyun Lee ,  Keith J. Park

IPC: A61B5/05 ,  A61B5/055 ,  A61B5/00

CPC classification number: A61B5/0555 ,  A61B5/708

Abstract: The present disclosure relates to a receive coil assembly for use in magnetic resonance imaging of breast tissue. In certain embodiments the assembly comprises separable parts: a configurable mechanical support and a flexible receive coil array. The adjustability and separability of the receive coil array relative to the mechanical support allows the receive coil array to substantially conform to the breasts of the patient during imaging.

Abstract translation: 本公开涉及一种用于乳腺组织的磁共振成像的接收线圈组件。 在某些实施例中，组件包括可分离部件：可配置的机械支撑件和柔性接收线圈阵列。 接收线圈阵列相对于机械支撑件的可调节性和可分离性允许接收线圈阵列在成像期间基本上符合患者的乳房。

公开(公告)号：US08908951B2

公开(公告)日：2014-12-09

申请号：US13728871

申请日：2012-12-27

Applicant: General Electric Company

Inventor： Marion Irene Menzel ,  Christopher Judson Hardy ,  Kevin Franklin King ,  Luca Marinelli ,  Ek Tsoon Tan ,  Jonathan Immanuel Sperl

IPC: G06K9/00 ,  G06T7/00

CPC classification number: G01R33/56341

Abstract: A magnetic resonance (MR) imaging method includes acquiring MR signals having phase and magnitude at q-space locations using a diffusion sensitizing pulse sequence performed on a tissue of interest, wherein the acquired signals each include a set of complex Fourier encodings representing a three-dimensional displacement distribution of the spins in a q-space location. The signals each include information relating to coherent motion and incoherent motion in the q-space location. The method also includes determining a contribution by coherent motion to the phase of the acquired MR signals; removing the phase contribution attributable to coherent motion from the acquired MR signals to produce a complex data set for each q-space location and an image of velocity components for each q-space location; and producing a three-dimensional velocity image from the image of the velocity components.

Abstract translation: 磁共振（MR）成像方法包括使用在感兴趣的组织上执行的扩散增感脉冲序列获取在q空间位置具有相位和幅度的MR信号，其中所获取的信号各自包括一组代表三维空间的复数傅里叶编码， 在q空间位置的自旋的三维位移分布。 每个信号包括与q空间位置中的相干运动和非相干运动有关的信息。 该方法还包括通过相干运动确定所获取的MR信号的相位的贡献; 从所获取的MR信号去除归因于相干运动的相位贡献，以产生用于每个q空间位置的复数据集合和用于每个q空间位置的速度分量的图像; 并根据速度分量的图像产生三维速度图像。

公开(公告)号：US20140296701A1

公开(公告)日：2014-10-02

申请号：US13852723

申请日：2013-03-28

Applicant: GENERAL ELECTRIC COMPANY

Inventor： Ileana Hancu ,  Kenneth William Rohling ,  Luca Marinelli ,  Eric William Fiveland ,  Seung-Kyun Lee ,  Keith J. Park

IPC: A61B5/055 ,  A61B5/00

CPC classification number: A61B5/0555 ,  A61B5/708

Abstract: The present disclosure relates to a receive coil assembly for use in magnetic resonance imaging of breast tissue. In certain embodiments the assembly comprises separable parts: a configurable mechanical support and a flexible receive coil array. The adjustability and separability of the receive coil array relative to the mechanical support allows the receive coil array to substantially conform to the breasts of the patient during imaging.

Abstract translation: 本公开涉及一种用于乳腺组织的磁共振成像的接收线圈组件。 在某些实施例中，组件包括可分离部件：可配置的机械支撑件和柔性接收线圈阵列。 接收线圈阵列相对于机械支撑件的可调节性和可分离性允许接收线圈阵列在成像期间基本上符合患者的乳房。

公开(公告)号：US20140159712A1

公开(公告)日：2014-06-12

申请号：US13970339

申请日：2013-08-19

Applicant: General Electric Company

Inventor： Dominic Michael Graziani ,  Thomas Kwok-Fah Foo ,  Luca Marinelli ,  Daniel Eugene Meyer ,  Bruce Allen Hay

IPC: G01N27/72

CPC classification number: G01R33/1276 ,  A61B5/00 ,  A61B5/0515

Abstract: Magnetic material imaging (MMI) system including first and second sets of field-generating coils. Each of the field-generating coils of the first and second sets has an elongated segment that extends along an imaging axis of the medical imaging system. The imaging axis extends through a region-of-interest (ROI) of an object. The elongated segments of the first set of field-generating coils are positioned opposite the elongated segments of the second set of field-generating coils and the ROI is located between the first and second sets of field-generating coils. The MMI system also includes a coil-control module configured to control a flow of current through the first and second sets of field-generating coils to generate a selection field and to generate a drive field. The selection and drive fields combine to form a movable 1D field free region (FFR) that extends through the ROI.

Abstract translation: 磁材料成像（MMI）系统包括第一组和第二组励磁线圈。 第一组和第二组的每个场产生线圈具有沿着医学成像系统的成像轴线延伸的细长部分。 成像轴延伸穿过物体的感兴趣区域（ROI）。 第一组场产生线圈的细长段与第二组场产生线圈的细长段相对设置，并且ROI位于第一组和第二组场产生线圈之间。 MMI系统还包括线圈控制模块，该线圈控制模块被配置为控制通过第一和第二组场产生线圈的电流流动以产生选择场并产生驱动场。 选择和驱动领域相结合，形成一个延伸穿过ROI的可移动1D无域区域（FFR）。

公开(公告)号：US11583188B2

公开(公告)日：2023-02-21

申请号：US16357023

申请日：2019-03-18

Applicant: General Electric Company

Inventor： Jhimli Mitra ,  Luca Marinelli ,  Asha Singanamalli

IPC: G06K9/00 ,  A61B5/02 ,  G06N3/088 ,  A61B8/08 ,  A61B5/00 ,  G06N20/00

Abstract: In accordance with the present disclosure, deep-learning techniques are employed to find anomalies corresponding to bleed events. By way of example, a deep convolutional neural network or combination of such networks may be trained to determine the location of a bleed event, such as an internal bleed event, based on ultrasound data acquired at one or more locations on a patient anatomy. Such a technique may be useful in non-clinical settings.