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公开(公告)号：US10957010B2
公开(公告)日：2021-03-23
申请号：US16534785
申请日：2019-08-07
Applicant: General Electric Company
Inventor： Soumya Ghose , Jhimli Mitra , David Martin Mills , Lowell Scott Smith , Desmond Teck Beng Yeo , Thomas Kwok-Fah Foo
Abstract: The subject matter discussed herein relates to the automatic, real-time registration of pre-operative magnetic resonance imaging (MRI) data to intra-operative ultrasound (US) data (e.g., reconstructed images or unreconstructed data), such as to facilitate surgical guidance or other interventional procedures. In one such example, brain structures (or other suitable anatomic features or structures) are automatically segmented in pre-operative and intra-operative ultrasound data. Thereafter, anatomic structure (e.g., brain structure) guided registration is applied between pre-operative and intra-operative ultrasound data to account for non-linear deformation of the imaged anatomic structure. MR images that are pre-registered to pre-operative ultrasound images are then given the same nonlinear spatial transformation to align the MR images with intra-operative ultrasound images to provide surgical guidance.
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公开(公告)号：US20190350554A1
公开(公告)日：2019-11-21
申请号：US15984541
申请日：2018-05-21
Applicant: General Electric Company
Inventor： Douglas Glenn Wildes , Lowell Scott Smith , Kwok Pong Chan , Vadim Bromberg , David Martin Mills , Warren Lee , Timothy James Fiorillo , Chi Tat Chiu
IPC: A61B8/00 , H01L27/20 , H01L41/047 , H01L41/09 , H01L41/293 , H01L21/78 , A61B8/08
Abstract: A grid of phased array transducers includes a piezoelectric layer and a plurality of ground contact traces. The piezoelectric layer includes a first side and a second side. The plurality of ground contact traces is disposed on the first side of the piezoelectric layer along an elevational direction, where each ground contact trace of the plurality of ground contact traces extends along an azimuthal direction. Further, each phased array transducer of the grid of phased array transducers is disposed between an adjacently disposed pair of ground contact traces of the plurality of ground contact traces. Moreover, each phased array transducer includes at least a portion of at least one ground contact trace of a corresponding pair of ground contact traces, and where each phased array transducer includes a plurality of transducer elements.
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3.发明申请公开(公告)号：US20180140278A1
公开(公告)日：2018-05-24
申请号：US15358160
申请日：2016-11-22
Applicant: General Electric Company
Inventor： Vadim Bromberg , Lowell Scott Smith , Douglas Glenn Wildes , Kwok Pong Chan , Reinhold Bruestle , Matthew Harvey Krohn , Chester Frank Saj
Abstract: An ultrasound transducer includes a transducer array having a plurality of transducer elements. The transducer array has a first side and a second side. Further, one or more ground electrodes are disposed on the first side of the transducer array, and one or more signal electrodes are disposed on the second side of the transducer array. Moreover, an acoustic backing structure is operatively coupled to the plurality of transducer elements of the transducer array. Also, a plurality of electrical traces is routed on a surface of the acoustic backing structure and operatively coupled to at least one of the one or more signal electrodes and one or more ground electrodes.
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4.发明申请METHODS AND SYSTEMS TO DETERMINE RESPIRATORY PHASE AND MOTION STATE DURING GUIDED RADIATION THERAPY 审中-公开在指导辐射治疗期间确定呼吸相位和运动状态的方法和系统公开(公告)号：US20170014645A1
公开(公告)日：2017-01-19
申请号：US15277198
申请日：2016-09-27
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Thomas Kwok-Fah Foo , Lowell Scott Smith , Kai Erik Thomenius , Sandeep Narendra Gupta , Luca Marinelli , Kedar Anil Patwardhan , Dominic Michael Graziani
Abstract: Methods and systems using magnetic resonance and ultrasound for tracking anatomical targets for radiation therapy guidance are provided. One system includes a patient transport configured to move a patient between and into a magnetic resonance (MR) system and a radiation therapy (RT) system. An ultrasound transducer is also provided that is hands-free and electronically steerable, securely attached to the patient, such that the ultrasound transducer is configured to acquire four-dimensional (4D) ultrasound images concurrently with one of an MR acquisition or an RT radiation therapy session. The system also includes a controller having a processor configured to use the 4D ultrasound images and MR images from the MR system to control at least one of a photon beam spatial distribution or intensity modulation generated by the RT system. The system determines the previously-acquired correct MR images that represent a specific motion state at some time, t, by a plurality of transformations that allow the representation of the position of fiducial markers in the corresponding ultrasound images to match that of a prior ultrasound acquisition.
Abstract translation: 提供了使用磁共振和超声波跟踪放射治疗指导解剖靶标的方法和系统。 一个系统包括被配置为将患者移动到磁共振（MR）系统和放射治疗（RT）系统之间）的患者输送。 还提供了一种超声换能器，其是免提的并且可电子操纵的，牢固地附接到患者，使得超声换能器被配置为与MR采集或RT放射治疗之一同时获取四维（4D）超声图像 会话 该系统还包括具有处理器的控制器，其被配置为使用来自MR系统的4D超声图像和MR图像来控制RT系统产生的光子束空间分布或强度调制中的至少一个。 该系统通过允许在对应的超声图像中的基准标记的位置的表示与先前的超声波获取相匹配的多个变换来确定在某时刻t表示特定运动状态的先前获得的正确MR图像 。
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公开(公告)号：US20210236858A1
公开(公告)日：2021-08-05
申请号：US16781823
申请日：2020-02-04
Applicant: General Electric Company
Inventor： Lowell Scott Smith , Luca Marinelli , Larry Y.L. Mo , Antonio Caiafa , David Shoudy
Abstract: In accordance with the present disclosure, ultrasound-based techniques using a combined scanning and treatment array module are employed to find and treat anomalies corresponding to bleed events. By way of example, ultrasound data may be acquired with a scanning array at one or more locations on a patient anatomy. A treatment array may deliver heat to a targeted anomaly to provide therapy. Such a technique may be useful outside of a hospital environment.
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Patent Agency Ranking
6.发明授权公开(公告)号：US10806947B2
公开(公告)日：2020-10-20
申请号：US15277198
申请日：2016-09-27
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Thomas Kwok-Fah Foo , Lowell Scott Smith , Kai Erik Thomenius , Sandeep Narendra Gupta , Luca Marinelli , Kedar Anil Patwardhan , Dominic Michael Graziani
Abstract: Methods and systems using magnetic resonance and ultrasound for tracking anatomical targets for radiation therapy guidance are provided. One system includes a patient transport configured to move a patient between and into a magnetic resonance (MR) system and a radiation therapy (RT) system. An ultrasound transducer is also provided that is hands-free and electronically steerable, securely attached to the patient, such that the ultrasound transducer is configured to acquire four-dimensional (4D) ultrasound images concurrently with one of an MR acquisition or an RT radiation therapy session. The system also includes a controller having a processor configured to use the 4D ultrasound images and MR images from the MR system to control at least one of a photon beam spatial distribution or intensity modulation generated by the RT system. The system determines the previously-acquired correct MR images that represent a specific motion state at some time, t, by a plurality of transformations that allow the representation of the position of fiducial markers in the corresponding ultrasound images to match that of a prior ultrasound acquisition.
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公开(公告)号：US10347818B2
公开(公告)日：2019-07-09
申请号：US15087369
申请日：2016-03-31
Applicant: General Electric Company
Inventor： Douglas Glenn Wildes , Lowell Scott Smith , Kwok Pong Chan , Vadim Bromberg
IPC: H01L41/33 , H01L41/27 , B06B1/06 , H03H3/02 , H01L41/047 , H01L41/09 , H01L41/113 , H01L41/277 , H01L41/29 , H03H9/205 , A61B8/00 , H03H3/04
Abstract: A manufacturing a process is provided for the bulk manufacture of transducer arrays, including arrays having at least one 3D printed (or otherwise additive manufactured) acoustic matching layers. In certain implementations, the manufactured transducers include a composite-piezoelectric transducer on a de-matching layer. In one implementation, by producing multiple arrays at once on a common carrier, and by using direct-deposit additive processes for the matching layers, the described processes greatly reduce the number of parts and the number of manual operations.
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公开(公告)号：US20180271372A1
公开(公告)日：2018-09-27
申请号：US15897964
申请日：2018-02-15
Applicant: General Electric Company
Inventor： Warren Lee , Eric William Fiveland , David Andrew Shoudy , Timothy Fiorillo , Kwok Pong Chan , Lowell Scott Smith , James Sabatini , David Martin Mills , Thomas Kwok-Fah Foo
CPC classification number: A61B5/0035 , A61B5/055 , A61B5/066 , A61B8/085 , A61B8/4416 , A61B8/4444 , A61B8/5261 , A61B8/5276 , A61B2562/182
Abstract: An ultrasound probe configured for use in a multi-modality imaging system includes a body including one or more electrical components of the ultrasound probe, an outermost housing enclosing the ultrasound probe, and an electromagnetic interference (EMI) shield disposed between the body and the housing, wherein the EMI shield is configured to reduce interference between the ultrasound probe and one or more different imaging systems of the multi-modality imaging system. The ultrasound probe further includes a transducer disposed on a patient-facing surface of the ultrasound probe and a cable coupled to the body and configured to communicatively couple the ultrasound probe to an ultrasound imaging system of the multi-modality imaging system, wherein the ultrasound probe comprises substantially non-ferromagnetic material.
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公开(公告)号：US20170288638A1
公开(公告)日：2017-10-05
申请号：US15087369
申请日：2016-03-31
Applicant: General Electric Company
Inventor： Douglas Glenn Wildes , Lowell Scott Smith , Kwok Pong Chan , Vadim Bromberg
IPC: H03H9/205 , B06B1/06 , H01L41/33 , H01L41/09 , H01L41/113 , H01L41/29 , A61B8/00 , H01L41/047
CPC classification number: H01L41/33 , A61B8/4281 , A61B8/4444 , A61B8/4483 , B06B1/0622 , H01L41/047 , H01L41/09 , H01L41/113 , H01L41/27 , H01L41/277 , H01L41/29 , H03H3/02 , H03H9/205 , H03H2003/0478 , Y10T29/42 , Y10T29/49005 , Y10T29/49798
Abstract: The present disclosure relates to the bulk manufacture of transducer arrays, including arrays having at least one 3D printed (or otherwise additive manufactured) acoustic matching layers. In certain implementations, the manufactured transducers include a composite-piezoelectric transducer on a de-matching layer. In one implementation, by producing multiple arrays at once on a common carrier, and by using direct-deposit additive processes for the matching layers, the described processes greatly reduce the number of parts and the number of manual operations.
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公开(公告)号：US20210042878A1
公开(公告)日：2021-02-11
申请号：US16534785
申请日：2019-08-07
Applicant: General Electric Company
Inventor： Soumya Ghose , Jhimli Mitra , David Martin Mills , Lowell Scott Smith , Desmond Teck Beng Yeo , Thomas Kwok-Fah Foo
Abstract: The subject matter discussed herein relates to the automatic, real-time registration of pre-operative magnetic resonance imaging (MRI) data to intra-operative ultrasound (US) data (e.g., reconstructed images or unreconstructed data), such as to facilitate surgical guidance or other interventional procedures. In one such example, brain structures (or other suitable anatomic features or structures) are automatically segmented in pre-operative and intra-operative ultrasound data. Thereafter, anatomic structure (e.g., brain structure) guided registration is applied between pre-operative and intra-operative ultrasound data to account for non-linear deformation of the imaged anatomic structure. MR images that are pre-registered to pre-operative ultrasound images are then given the same nonlinear spatial transformation to align the MR images with intra-operative ultrasound images to provide surgical guidance.
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