公开(公告)号：US20220265920A1

公开(公告)日：2022-08-25

申请号：US17735616

申请日：2022-05-03

Applicant: AMGEN INC.

Inventor： Lawrence S. Ring ,  Dhairya Mehta ,  Stephanie Toy ,  Ferry Tamtoro ,  Alexander Stuart Cairns ,  Scott R. Gibson

IPC: A61M5/142 ,  A61M25/02 ,  A61M5/20 ,  A61M5/32 ,  A61M5/42 ,  A61M25/00 ,  C12N9/64 ,  C07K14/535 ,  A61K38/19 ,  A61K38/28 ,  A61K38/26 ,  A61M5/158 ,  A61M5/14 ,  A61M5/31 ,  A61K9/00

Abstract: A drug delivery device includes a blunt cannula and a reservoir. The blunt cannula has a cylindrical wall that defines an axial passage between a first end and a second end of the blunt cannula. The wall has at least a first tapered region at the first end to define an opening in fluid communication with the axial passage and adapted at the first end to resist interruption of fluid flow through the axial passage and out of the first end of the blunt cannula. The reservoir is connected to the second end of the blunt cannula.

公开(公告)号：US20190275241A1

公开(公告)日：2019-09-12

申请号：US16297408

申请日：2019-03-08

Applicant: AMGEN INC.

Inventor： Lawrence S. Ring ,  Tohid Pirbodaghi ,  Samin Akbari ,  Daniel Eduardo Groszmann ,  Mehran Mojarrad ,  Mark Gordon ,  Mikhail Tikh ,  Jimmie L. Ward ,  Scott R. Gibson ,  Sheldon B. Moberg ,  Joshua Tamsky ,  Paul Faucher

IPC: A61M5/168 ,  A61M5/158 ,  A61M39/24

Abstract: A drug delivery device includes a housing defining a shell and an inner volume, a container, a drive mechanism, a needle assembly, a fluid flow connection, and a backflow prevention mechanism. The container has an inner volume to contain a medicament to be administered to a user. The drive mechanism is at least partially disposed within the housing and exerts a force to urge the medicament out the container. The fluid flow connection is coupled to the container and the needle assembly and allows the medicament to flow from the container to the needle assembly to be administered. The backflow prevention mechanism is associated with at least one of the container, the fluid flow connection, or the needle assembly and includes at least one flow restrictor to restrict a fluid from flowing from the needle assembly to the container.