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公开(公告)号：US12042642B2
公开(公告)日：2024-07-23
申请号：US17264157
申请日：2019-09-17
Applicant: AMGEN INC.
Inventor： Sudeshna Dutta Ray , Scott Robert Gibson , Daniel Eduardo Groszmann , Mehran Mojarrad , Andrew James Carlson , Lee Gordon Macklem , Mikhail Tikh
CPC classification number: A61M5/31576 , A61M5/14248 , A61M5/1452 , A61M2005/1585 , A61M2005/31588 , A61M2205/52
Abstract: Drug delivery devices are described that include an escapement activation assembly. The escapement activation assembly includes a slide having a plurality of pallet engagement portions and a switch engagement portion and a pallet having a plurality of slide engagement portions. A drive is coupled to the pallet to cause the pallet to move relative to the slide to move the plurality of slide engagement portions into and out of engagement with the plurality of pallet engagement portions to allow the slide to move along a path within the drug delivery device. Movement of the slide can cause the switch engagement portion to move out of engagement with an activation trigger of a mechanism of the drug delivery device.
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公开(公告)号：US11890450B2
公开(公告)日：2024-02-06
申请号：US16297408
申请日：2019-03-08
Applicant: AMGEN INC.
Inventor： Lawrence Scott Ring , Tohid Pirbodaghi , Samin Akbari , Daniel Eduardo Groszmann , Mehran Mojarrad , Mark Gordon , Mikhail Tikh , Jimmie L. Ward , Scott R. Gibson , Sheldon B. Moberg , Joshua Tamsky , Paul Faucher , Jeff Lind
CPC classification number: A61M5/16813 , A61M5/1413 , A61M5/14248 , A61M5/158 , A61M5/16822 , A61M39/24 , A61M5/14526 , A61M5/155 , A61M2005/1403 , A61M2005/1406 , A61M2005/14252 , A61M2039/244 , A61M2039/2406 , A61M2039/248 , A61M2039/2426 , A61M2205/3561 , A61M2205/505 , A61M2205/7527 , A61M2205/7536 , A61M2209/045
Abstract: A drug delivery device includes a housing defining a shell and an inner volume, a container, a drive mechanism, a needle assembly, a fluid flow connection, and a backflow prevention mechanism. The container has an inner volume to contain a medicament to be administered to a user. The drive mechanism is at least partially disposed within the housing and exerts a force to urge the medicament out the container. The fluid flow connection is coupled to the container and the needle assembly and allows the medicament to flow from the container to the needle assembly to be administered. The backflow prevention mechanism is associated with at least one of the container, the fluid flow connection, or the needle assembly and includes at least one flow restrictor to restrict a fluid from flowing from the needle assembly to the container.
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公开(公告)号：US20210228811A1
公开(公告)日：2021-07-29
申请号：US17264157
申请日：2019-09-17
Applicant: AMGEN INC.
Inventor： Sudeshna Dutta Ray , Scott Robert Gibson , Daniel Eduardo Groszmann , Mehran Mojarrad , Andrew James Carlson , Lee Gordon Macklem , Mikhail Tikh
Abstract: Drug delivery devices are described that include an escapement activation assembly. The escapement activation assembly includes a slide having a plurality of pallet engagement portions and a switch engagement portion and a pallet having a plurality of slide engagement portions. A drive is coupled to the pallet to cause the pallet to move relative to the slide to move the plurality of slide engagement portions into and out of engagement with the plurality of pallet engagement portions to allow the slide to move along a path within the drug delivery device. Movement of the slide can cause the switch engagement portion to move out of engagement with an activation trigger of a mechanism of the drug delivery device.
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公开(公告)号：US20190275241A1
公开(公告)日：2019-09-12
申请号：US16297408
申请日：2019-03-08
Applicant: AMGEN INC.
Inventor： Lawrence S. Ring , Tohid Pirbodaghi , Samin Akbari , Daniel Eduardo Groszmann , Mehran Mojarrad , Mark Gordon , Mikhail Tikh , Jimmie L. Ward , Scott R. Gibson , Sheldon B. Moberg , Joshua Tamsky , Paul Faucher
Abstract: A drug delivery device includes a housing defining a shell and an inner volume, a container, a drive mechanism, a needle assembly, a fluid flow connection, and a backflow prevention mechanism. The container has an inner volume to contain a medicament to be administered to a user. The drive mechanism is at least partially disposed within the housing and exerts a force to urge the medicament out the container. The fluid flow connection is coupled to the container and the needle assembly and allows the medicament to flow from the container to the needle assembly to be administered. The backflow prevention mechanism is associated with at least one of the container, the fluid flow connection, or the needle assembly and includes at least one flow restrictor to restrict a fluid from flowing from the needle assembly to the container.
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