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    Drug delivery system with temperature-sensitive control
    14.
    发明授权
    Drug delivery system with temperature-sensitive control 有权

    公开(公告)号：US11383047B2

    公开(公告)日：2022-07-12

    申请号：US16589037

    申请日：2019-09-30

    Applicant: AMGEN INC.

    Inventor： Scott R. Gibson ,  Mark Ka Lai Lee ,  Donald Busby ,  Stephanie Toy ,  Suhas Krishna ,  Francisca Tan-Malecki ,  Ferry Tamtoro

    IPC: A61M5/44 ,  A61M5/315 ,  A61M5/20 ,  A61M5/142 ,  A61M5/162 ,  A61M5/172 ,  A61M5/31

    Abstract: A drug delivery system includes a reservoir and a drug delivery device coupled to the reservoir. The drug delivery device also may include at least one temperature-sensitive component and a lock having locked and unlocked states. The system further includes an output device, and a controller coupled to the lock and the output device. The controller may also include a temperature sensor, or may be coupled to the temperature sensor. The controller is programmed or configured to determine if the temperature of a drug in the reservoir or of the temperature-sensitive component exceeds an upper limit or is below a lower limit, and to activate the lock in either event. The controller is also programmed or configured to determine, directly or indirectly, if the temperature subsequently is between the upper and lower limits, and to unlock lock as a consequence.

    Drug delivery system with temperature-sensitive control
    16.
    发明授权
    Drug delivery system with temperature-sensitive control 有权

    公开(公告)号：US10758683B2

    公开(公告)日：2020-09-01

    申请号：US14913928

    申请日：2014-10-22

    Applicant: AMGEN INC.

    Inventor： Scott R. Gibson ,  Mark Ka Lai Lee ,  Donald Busby ,  Stephanie Toy ,  Suhas Krishna ,  Francisca Tan-Malecki ,  Ferry Tamtoro

    IPC: A61M5/44 ,  A61M5/162 ,  A61M5/315 ,  A61M5/20 ,  A61M5/142 ,  A61M5/172 ,  A61M5/31

    Abstract: A drug delivery system includes a reservoir and a drug delivery device coupled to the reservoir. The drug delivery device also may include at least one temperature-sensitive component and a lock having locked and unlocked states. The system further includes an output device, and a controller coupled to the lock and the output device. The controller may also include a temperature sensor, or may be coupled to the temperature sensor. The controller is programmed or configured to determine if the temperature of a drug in the reservoir or of the temperature-sensitive component exceeds an upper limit or is below a lower limit, and to activate the lock in either event. The controller is also programmed or configured to determine, directly or indirectly, if the temperature subsequently is between the upper and lower limits, and to unlock lock as a consequence.

    Autoinjector
    17.
    发明授权
    Autoinjector 有权

    公开(公告)号：US10398854B2

    公开(公告)日：2019-09-03

    申请号：US14434347

    申请日：2013-10-18

    Applicant: Amgen Inc.

    Inventor： Valerie M. Fenster ,  Stephanie Toy ,  Mark Ka Lai Lee ,  Denise Meyer

    IPC: A61M5/42 ,  A61M5/20 ,  A61M5/32 ,  A61M5/50

    Abstract: An injector such as a needle-type autoinjector having a flexible flange disposed at an injection end of the injector for stretching or pinching the skin of the injection site. The flexible flange may be removably attached to the injector or integrated into the injector during manufacturing. Further, an injector having a palm button disposed at an activation end of the injector for activating an injection cycle of the injector. The palm button may be removably attached to the injector or integrated into the injector during manufacturing. Still further, a holding device for one-handed operation of an injector, the holding device having a sleeve and at least one hand rest coupled to the sleeve, the sleeve and hand rest providing ergonomic holding and operation of the injector. Still further, autoinjector needle shield having an enlarged, rounded lip for contacting the skin at the injection site.

    Drug Delivery System With Temperature-Sensitive Control
    19.
    发明申请
    Drug Delivery System With Temperature-Sensitive Control 审中-公开
    具有温度敏感控制的药物输送系统

    公开(公告)号：US20160354555A1

    公开(公告)日：2016-12-08

    申请号：US14913928

    申请日：2014-10-22

    Applicant: AMGEN INC.

    Inventor： Scott R. Gibson ,  Lee Foster ,  Donald Busby ,  Stephanie Toy ,  Suhas Krishna ,  Francisca Tan-Malecki ,  Ferry Tamtoro

    IPC: A61M5/44 ,  A61M5/31 ,  A61M5/172 ,  A61M5/142 ,  A61M5/162

    Abstract: A drug delivery system includes a reservoir and a drug delivery device coupled to the reservoir. The drug delivery device also may include at least one temperature-sensitive component and a lock having locked and unlocked states. The system further includes an output device, and a controller coupled to the lock and the output device. The controller may also include a temperature sensor, or may be coupled to the temperature sensor. The controller is programmed or configured to determine if the temperature of a drug in the reservoir or of the temperature-sensitive component exceeds an upper limit or is below a lower limit, and to activate the lock in either event. The controller is also programmed or configured to determine, directly or indirectly, if the temperature subsequently is between the upper and lower limits, and to unlock lock as a consequence.

    Abstract translation: 药物递送系统包括联接到储存器的储存器和药物输送装置。 药物递送装置还可以包括至少一个温度敏感组件和具有锁定和解锁状态的锁。 该系统还包括输出装置和耦合到锁和输出装置的控制器。 控制器还可以包括温度传感器，或者可以耦合到温度传感器。 控制器被编程或配置为确定储存器或温度敏感组件中的药物的温度是否超过上限或低于下限，并且在任一情况下激活锁定。 控制器也被编程或配置为直接或间接地确定温度是否在上限和下限之间，并因此解锁锁定。

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