公开(公告)号：US20160263079A1

公开(公告)日：2016-09-15

申请号：US15160239

申请日：2016-05-20

Applicant: AMOREPACIFIC CORPORATION

Inventor： Byung Gyu KIM ,  Hyun Woo JEONG ,  Su Kyung KIM ,  Si Young CHO ,  Chan Woong PARK ,  Dae Bang SEO ,  Wan Gi KIM ,  Sang Jun LEE

IPC: A61K31/34 ,  A23L2/52 ,  A61K36/258

CPC classification number: A61K31/34 ,  A23L2/52 ,  A23L33/105 ,  A23L33/11 ,  A23V2002/00 ,  A61K36/258

Abstract: The present invention relates to a compound of Formula 1, and an SIRT 1 activator including, as an active ingredient, derivatives thereof or pharmaceutically acceptable salts thereof. The present invention also relates to a composition including the SIRT 1 activator for detoxification, for the improvement of metabolic disorders, for the prevention or improvement of eye diseases, or the prevention or improvement of immune diseases.

公开(公告)号：US20160263078A1

公开(公告)日：2016-09-15

申请号：US15160218

申请日：2016-05-20

Applicant: AMOREPACIFIC CORPORATION

Inventor： Byung Gyu KIM ,  Hyun Woo JEONG ,  Su Kyung KIM ,  Si Young CHO ,  Chan Woong PARK ,  Dae Bang SEO ,  Wan Gi KIM ,  Sang Jun LEE

IPC: A61K31/34 ,  A61K36/258

CPC classification number: A61K31/34 ,  A23L2/52 ,  A23L33/105 ,  A23L33/11 ,  A23V2002/00 ,  A61K36/258

Abstract: The present invention relates to a compound of Formula 1, and an SIRT 1 activator including, as an active ingredient, derivatives thereof or pharmaceutically acceptable salts thereof. The present invention also relates to a composition including the SIRT 1 activator for detoxification, for the improvement of metabolic disorders, for the prevention or improvement of eye diseases, or the prevention or improvement of immune diseases.

公开(公告)号：US20240390320A1

公开(公告)日：2024-11-28

申请号：US18663736

申请日：2024-05-14

Applicant: AMOREPACIFIC CORPORATION

Inventor： Hyun Woo JEONG ,  Wanki KIM ,  Jong Hwa ROH

IPC: A61K31/353 ,  A61K31/7048 ,  A61P3/04

Abstract: Disclosed herein is a method for inhibiting lipogenesis; inhibiting fat accumulation; promoting fat breakdown; reducing body fat; and/or preventing, improving or treating obesity or metabolic diseases. In one aspect, Gallocatechin Gallate (GCG) and Isoquercitrin (IQC) of the present invention have excellent lipid metabolism control effects, can increase mitochondria in adipocytes, and promote the production of brown fat. Therefore, in one aspect, the present invention can provide a method for preventing, improving, or treating obesity or metabolic diseases.

公开(公告)号：US20230372417A1

公开(公告)日：2023-11-23

申请号：US18313465

申请日：2023-05-08

Applicant: AMOREPACIFIC CORPORATION

Inventor： Hyun Woo JEONG ,  Donghyun CHO ,  Wanki KIM ,  Jong Hwa ROH

IPC: A61K35/747 ,  A23L33/135 ,  A61P1/16

CPC classification number: A61K35/747 ,  A23L33/135 ,  A61P1/16 ,  A23Y2220/67

Abstract: A method for improving hepatic function, including administering an effective amount of a composition including a green tea-derived Lactiplantibacillus plantarum strain; a culture of the strain; a lysate of the strain; an extract of the strain; an extract of the culture; or an extract of the lysate to a subject in need thereof is disclosed in the specification.

公开(公告)号：US20220218778A1

公开(公告)日：2022-07-14

申请号：US17570765

申请日：2022-01-07

Applicant: AMOREPACIFIC CORPORATION

Inventor： Hyun Woo JEONG ,  Si Young CHO ,  Yong Deog HONG ,  Wanki KIM ,  Miyoung PARK

IPC: A61K36/82 ,  A61K31/352 ,  A61K9/20 ,  A61K9/16 ,  A61K9/00 ,  A61P3/04

Abstract: The present disclosure relates to a composition for reducing body fat, which contains a green tea extract containing 4 wt % or more of gallocatechin gallate based on the total weight of the extract as an active ingredient, and a method for preparing the same. The composition according to the present disclosure provides a superior effect of reducing body fat as the green tea extract containing gallocatechin gallate is contained as an active ingredient. Accordingly, it can provide substances effective for treating obesity through various researches.

公开(公告)号：US20210298339A1

公开(公告)日：2021-09-30

申请号：US17217809

申请日：2021-03-30

Applicant: AMOREPACIFIC CORPORATION

Inventor： Su Hwan KIM ,  Sangyoul NA ,  Hyun Woo JEONG ,  Wanki KIM ,  Jisung KIM ,  Chan Woong PARK

IPC: A23L33/105 ,  A23L33/21 ,  A23L29/269 ,  A23D9/007

Abstract: The present disclosure relates to an emulsion composition containing ginseng seed oil and ginseng berry extract, wherein the composition is a single phase. Whereas the existing composition containing a water-soluble ingredient as a main ingredient has the problem that, when ginseng seed oil is added, formulation stability is decreased as the ginseng seed oil is separated from the water-soluble ingredient, the emulsion composition according to the present disclosure exhibits superior stability because the ginseng seed oil is uniformly mixed with the water-soluble ingredient and separation of the ginseng seed oil from the water-soluble ingredient does not occur fora long period of time.

公开(公告)号：US20210093651A1

公开(公告)日：2021-04-01

申请号：US17031147

申请日：2020-09-24

Applicant: AMOREPACIFIC CORPORATION

Inventor： Yong Deog HONG ,  Hyun Woo JEONG

IPC: A61K31/704 ,  A61K36/258 ,  A61K8/97 ,  A61K8/63 ,  A61P17/00 ,  A61Q19/08

Abstract: The present disclosure relates to a composition comprising (20S,24R)-6-O-β-D-glucopyranosyl(1→2)-β-D-glucopyranoside-dammar-3-one-20,24-epoxy-6a,12b,25-triol, which is a novel ginsenoside, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof as an active ingredient. In addition, it relates to a method for improving skin elasticity or skin wrinkles, which comprises administering an effective amount of (20S,24R)-6-O-β-D-glucopyranosyl(1→2)-β-D-glucopyranoside-dammar-3-one-20,24-epoxy-6a,12b,25-triol, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof to a subject in need thereof. The novel ginsenoside, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof has a superior effect of improving skin elasticity and skin wrinkles.

公开(公告)号：US20200121580A1

公开(公告)日：2020-04-23

申请号：US16656082

申请日：2019-10-17

Applicant: AMOREPACIFIC CORPORATION

Inventor： Yong Deog HONG ,  Hyun Woo JEONG

IPC: A61K8/63 ,  A61Q19/02

Abstract: The present specification relates to a composition containing novel (20S,24R)-6-O-β-D-glucopyranosyl(1→2)-β-D-glucopyranoside-dammar-3-one-20,24-epoxy-6a,12b,25-triol, a pharmaceutically acceptable salt thereof, a hydrate or a solvate thereof as an active ingredient. The composition exhibits an excellent skin brightening effect.

公开(公告)号：US20240350576A1

公开(公告)日：2024-10-24

申请号：US18618666

申请日：2024-03-27

Applicant: AMOREPACIFIC CORPORATION

Inventor： Hyun Woo JEONG ,  Jinoh Chung ,  Wanki Kim ,  Jong Hwa Roh

IPC: A61K36/82 ,  A61K38/01

CPC classification number: A61K36/82 ,  A61K38/011

Abstract: The present disclosure relates to a method for lowering blood sugar including administering an effective amount of a green tea peptide composition to a subject in need thereof, and specifically, the green tea peptide composition according to the present disclosure exhibits a blood sugar-lowering effect through excellent stimulation of glucose transport in adipocytes, inhibition of gluconeogenesis in hepatocytes, and DPP-4 inhibitory activity, and can be applied to various health functional food compositions and pharmaceutical compositions.

公开(公告)号：US20210093653A1

公开(公告)日：2021-04-01

申请号：US17031057

申请日：2020-09-24

Applicant: AMOREPACIFIC CORPORATION

Inventor： Yong Deog HONG ,  Hyun Woo JEONG

IPC: A61K31/7048 ,  A61K36/258

Abstract: The present disclosure relates to a composition comprising (20S,24R)-6-O-β-D-glucopyranosyl(1→2)-β-D-glucopyranoside-dammar-3-one-20,24-epoxy-6a,12b,25-triol, which is a novel ginsenoside, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof as an active ingredient. In addition, it relates to a method for preventing or improving menopausal symptoms, which comprises administering an effective amount of (20S,24R)-6-O-β-D-glucopyranosyl(1→2)-β-D-glucopyranoside-dammar-3-one-20,24-epoxy-6a,12b,25-triol, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof to a subject in need thereof. The novel ginsenoside has a superior effect of preventing or improving menopausal symptoms with a low risk of breast cancer.