Abstract:
A composition includes, as an active ingredient, a substance capable of providing a useful effect to the skin by stimulating production of beta (β)-endorphin. The composition containing, as an active ingredient, sanshool, an isomer thereof, a hydrate thereof, or a solvate thereof stimulates production of β-endorphin when applied into the body, thereby providing useful effects to the skin, such as relieving skin irritation from the outside and providing a skin soothing effect.
Abstract:
The present invention relates to a composition for life extension and particularly to a composition for life extension containing a ginseng fruit extract. The present invention can extend the life of an individual by containing the ginseng fruit extract as an active ingredient and thus is medically highly useful.
Abstract:
The disclosure relates to the method for alleviating skin irritation or inhibiting sebum production, which includes administering a composition including a compound represented by Chemical Formula 1, a salt thereof, a stereoisomer thereof, a hydrate thereof, or a solvate thereof as an active ingredient to a subject in need of alleviating skin irritation or inhibiting sebum production, and specifically the composition can alleviate the irritation of the skin stimulated by ultraviolet rays, and more specifically, the composition can alleviate the skin irritation by reducing inflammatory factors in the cells of the skin stimulated by simultaneous stimulation of UVA and UVB ultraviolet rays, and in addition, specifically, it is possible to suppress the sebum production by inhibiting intracellular lipid synthesis with the composition, and more specifically, the sebum production of the skin can be suppressed by reducing the expression level of the factors related to intracellular lipid synthesis with the composition.
Abstract:
The present invention relates to a compound of Formula 1, and an SIRT 1 activator including, as an active ingredient, derivatives thereof or pharmaceutically acceptable salts thereof. The present invention also relates to a composition including the SIRT 1 activator for detoxification, for the improvement of metabolic disorders, for the prevention or improvement of eye diseases, or the prevention or improvement of immune diseases.
Abstract:
The present invention relates to a compound of Formula 1, and an SIRT 1 activator including, as an active ingredient, derivatives thereof or pharmaceutically acceptable salts thereof. The present invention also relates to a composition including the SIRT 1 activator for detoxification, for the improvement of metabolic disorders, for the prevention or improvement of eye diseases, or the prevention or improvement of immune diseases.
Abstract:
The present disclosure relates to a composition for reducing body fat, which contains a green tea extract containing 4 wt % or more of gallocatechin gallate based on the total weight of the extract as an active ingredient, and a method for preparing the same. The composition according to the present disclosure provides a superior effect of reducing body fat as the green tea extract containing gallocatechin gallate is contained as an active ingredient. Accordingly, it can provide substances effective for treating obesity through various researches.
Abstract:
The present disclosure relates to a method for preventing, alleviating, improving or treating female hormone regulation disorder or symptoms, which contains a green tea extract with contents of ingredients changed. Specifically, the method according to an aspect of the present disclosure includes a step of administering an effective amount of a green tea extract, which contains (−)-gallocatechin gallate (GCG) and (−)-epigallocatechin gallate (EGCG) at specific contents, to a subject in need thereof, and may exhibit an effect of preventing, alleviating, improving or treating female hormone regulation disorder or symptoms.
Abstract:
Disclosed is to provide a composition for skin-whitening or preventing or improving skin wrinkles, comprising a green tea extract which has modified amounts of ingredients. More specifically, the extract and composition according to one aspect of the present disclosure are derived from natural plants that cause less irritation to the skin and are eco-friendly, thus they are safe, and thereby the extract and composition can exhibit excellent effects of effectively inhibiting melanin production and tyrosinase activity and preventing or improving skin whitening, and can exhibit excellent effects of effectively inhibiting the expression of MMP-1 and preventing or improving skin wrinkles.
Abstract:
The present specification relates to a novel quercetin-based compound separated from post fermented tea, an isomer thereof, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof, the compound being capable of being widely used in post fermented tea-related industries and various fields in which the compound may be used.
Abstract:
Disclosed herein is a method for senotherapy; prevention, improvement or treatment of aging-related disease; improvement of skin elasticity or wrinkles; improvement of skin barrier; or improvement of skin pigmentation, containing administering an effective amount of tea tree (Camellia Sinensis) root extract to a subject in need thereof. In one aspect, a senotherapy composition containing the tea tree (Camellia Sinensis) root extract has an excellent senolytic effect to selectively remove senescent cells and an excellent senomorphic effect to inhibit the production of senescence associated secretory phenotype (SASP) of senescent cells.