COMPOSITION FOR SUPPRESSING SKIN IRRITATION OR INHIBITING SEBUM SECRETION

    公开(公告)号:US20230363997A1

    公开(公告)日:2023-11-16

    申请号:US18153467

    申请日:2023-01-12

    CPC classification number: A61K8/498 A61Q19/005 A61Q19/004

    Abstract: The disclosure relates to the method for alleviating skin irritation or inhibiting sebum production, which includes administering a composition including a compound represented by Chemical Formula 1, a salt thereof, a stereoisomer thereof, a hydrate thereof, or a solvate thereof as an active ingredient to a subject in need of alleviating skin irritation or inhibiting sebum production, and specifically the composition can alleviate the irritation of the skin stimulated by ultraviolet rays, and more specifically, the composition can alleviate the skin irritation by reducing inflammatory factors in the cells of the skin stimulated by simultaneous stimulation of UVA and UVB ultraviolet rays, and in addition, specifically, it is possible to suppress the sebum production by inhibiting intracellular lipid synthesis with the composition, and more specifically, the sebum production of the skin can be suppressed by reducing the expression level of the factors related to intracellular lipid synthesis with the composition.

    NOVEL QUERCETIN-BASED COMPOUND
    9.
    发明申请

    公开(公告)号:US20190241601A1

    公开(公告)日:2019-08-08

    申请号:US16343307

    申请日:2017-10-16

    Abstract: The present specification relates to a novel quercetin-based compound separated from post fermented tea, an isomer thereof, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof, the compound being capable of being widely used in post fermented tea-related industries and various fields in which the compound may be used.

    SENOTHERAPY COMPOSITION CONTAINING CAMELLIA SINENSIS EXTRACT

    公开(公告)号:US20250000786A1

    公开(公告)日:2025-01-02

    申请号:US18757797

    申请日:2024-06-28

    Abstract: Disclosed herein is a method for senotherapy; prevention, improvement or treatment of aging-related disease; improvement of skin elasticity or wrinkles; improvement of skin barrier; or improvement of skin pigmentation, containing administering an effective amount of tea tree (Camellia Sinensis) root extract to a subject in need thereof. In one aspect, a senotherapy composition containing the tea tree (Camellia Sinensis) root extract has an excellent senolytic effect to selectively remove senescent cells and an excellent senomorphic effect to inhibit the production of senescence associated secretory phenotype (SASP) of senescent cells.

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