公开(公告)号：US20180116939A1

公开(公告)日：2018-05-03

申请号：US15560879

申请日：2016-03-14

Applicant: AMOREPACIFIC CORPORATION

Inventor： Jae Won YOU ,  Tae Hun PARK ,  Yong-Jin KIM ,  Jon Hwan LEE

IPC: A61K8/68 ,  A61K8/60 ,  A61Q19/00 ,  A61K31/133 ,  A61P17/10 ,  A61P31/04 ,  C07H15/04 ,  C07C215/10

CPC classification number: A61K8/68 ,  A61K8/60 ,  A61K31/133 ,  A61P17/10 ,  A61P31/04 ,  A61Q19/00 ,  C07C215/10 ,  C07H15/04 ,  C07H15/12

Abstract: The present invention relates to a phytospingosine derivative generated by a condensation reaction of phytospingosine and maltose or lactose, which is an aldose-based disaccharide, and to a composition containing the same. The phytospingosine derivative of the present invention has high solubility in water compared with phytospingosine, is easy to formulate since the stabilization problem in a solution is solved, and maintains or further enhances the antibacterial effect of phytospingosine.

公开(公告)号：US20180116933A1

公开(公告)日：2018-05-03

申请号：US15561428

申请日：2016-03-29

Applicant: Amorepacific Corporation

Inventor： Yung Hyup JOO ,  Heung Soo BAEK ,  Jeong Ah HWANG ,  Hae Kwang LEE ,  Yongjin KIM ,  Hong-Ju SHIN ,  Jon Hwan LEE

IPC: A61K8/42 ,  A61Q19/08 ,  A61K31/166 ,  A23L33/00 ,  A23L33/15 ,  A23L33/155 ,  A23L33/16 ,  A23L2/52

CPC classification number: A61K8/42 ,  A23L2/52 ,  A23L33/15 ,  A23L33/155 ,  A23L33/16 ,  A23L33/30 ,  A23V2002/00 ,  A61K8/30 ,  A61K8/34 ,  A61K31/166 ,  A61Q19/08

Abstract: 5-Adamantan-1-yl-N-(2,4-dihydroxybenzyl)-2,4-dimethoxybenzamide disclosed in the present specification can exhibit excellent anti-oxidative and anti-aging effects while having no toxicity. For example, the compound exhibits excellent anti-oxidative and anti-aging effects by scavenging free radicals or inhibiting MMP-1 expression.