利索-全球专利检索

  1. Login
  2. Sign Up

Search Results

18 records (took 0.027 seconds)

    Use of 2,5-Dihydroxybenzenesulfonic Acid in the Manufacturing of Medicines, Applicable to the Treatment of Angiodependent Diseases
    13.
    发明申请
    Use of 2,5-Dihydroxybenzenesulfonic Acid in the Manufacturing of Medicines, Applicable to the Treatment of Angiodependent Diseases 审中-公开
    2,5-二羟基苯磺酸在药物制造中的应用，适用于治疗依从性疾病

    公开(公告)号：US20130203851A1

    公开(公告)日：2013-08-08

    申请号：US13772790

    申请日：2013-02-21

    Applicant: AmDerma Pharmaceuticals, LLC

    Inventor： Pedro Cuevas Sànchez ,  Antonio Romero Garrido ,  Guillermo Gimenez Gallego ,  Serafin Valverde Lopez ,  Rosa Maria Lozano Puerto

    IPC: A61K31/185

    CPC classification number: A61K31/185

    Abstract: Provided is the use of 2,5-dihydroxybenzenesulfonic acid in the production of medicaments for the treatment of angiodependent diseases. More specifically, described is the use of the aforesaid compound and, in particular, the calcium and potassium salts thereof, for the treatment of two angiodependent diseases, which present a reduction in the apoptosis, namely cancer and psoriasis. Also described is the antiproliferative, antimigratory, antiangiogenic and proapoptotic capacity of said family of compounds in non-quiescent cells. In addition, described is the potentiating effect of said compounds on known cytostatic medicines in the treatment of tumours and, specifically, on gliomas. Additionally, the therapeutic efficacy of said compounds, based on the combined anti proliferative, antiangiogenic and proapaptotic capacities thereof, in the treatment of chronic psoriatic plaques is provided.

    Abstract translation: 提供2,5-二羟基苯磺酸在制备用于治疗血管病的药物中的用途。 更具体地，描述了上述化合物，特别是其钙和钾盐用于治疗呈现细胞凋亡降低（即癌症和牛皮癣）的两种血液依赖性疾病的用途。 还描述了所述家族化合物在非静止细胞中的抗增殖，抗反应，抗血管生成和促凋亡能力。 此外，描述了所述化合物对已知的细胞生长抑制药物治疗肿瘤，特别是胶质瘤的增强作用。 另外，提供了所述化合物在治疗慢性银屑病斑块中基于组合的抗增殖，抗血管生成和促血细胞生成能力的治疗功效。

Patent Agency Ranking