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公开(公告)号：US20110295271A1
公开(公告)日：2011-12-01
申请号：US13161383
申请日：2011-06-15
IPC分类号： A61B19/00
CPC分类号： A61B19/26 , A61B90/11 , A61B90/39 , A61B90/50 , A61B2017/3407 , A61B2090/363
摘要： In one aspect, an apparatus for supporting an adjustable surgical platform is disclosed. In one embodiment, the apparatus includes a supporting platform portion with a body portion that defines bore along a central axis. Arm portions with engaging means extend radially from the supporting platform portion. The apparatus also includes a shaft portion extending from the supporting platform portion in a first direction, with a shaft body portion that defines a bore along a longitudinal axis B. The bore of the shaft body portion is in communication with the bore of the supporting platform portion. The apparatus further includes a base portion connected to the shaft portion, and that defines a bore in communication with the bore of the shaft portion and the bore of the supporting platform portion. Mounting means are configured to secure the base portion to a region of interest of a living subject.
摘要翻译： 一方面，公开了一种用于支撑可调节手术平台的装置。 在一个实施例中，该装置包括具有主体部分的支撑平台部分，该主体部分沿着中心轴线限定孔。 具有接合装置的臂部分从支撑平台部分径向延伸。 该装置还包括从支撑平台部分沿第一方向延伸的轴部分，轴主体部分沿着纵向轴线B限定孔。轴体部分的孔与支撑平台的孔连通 一部分。 该装置还包括连接到轴部分的基部，并且限定与轴部分的孔和支撑平台部分的孔连通的孔。 安装装置构造成将基部固定到活体的感兴趣区域。
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12.发明申请公开(公告)号：US20110160800A1
公开(公告)日：2011-06-30
申请号：US13044948
申请日：2011-03-10
IPC分类号： A61N1/36
CPC分类号： A61N1/0534 , A61N1/36082
摘要： A method for programming a deep brain stimulator implanted in a target region of a brain of a living subject for optimal stimulation, wherein the deep brain stimulator comprises at least one electrode having a plurality of electrode contacts spaced apart from each other, and any portion of the brain of the living subject is identifiable by a set of corresponding spatial coordinates. In one embodiment, the method comprises the steps of creating an efficacy atlas in which any spatial coordinates for a position in a target region of the brain of the living subject are related to a position with corresponding atlas coordinates in the efficacy atlas, and each position in the atlas coordinates of the efficacy atlas is associated with an efficacy of stimulation at a corresponding position in the spatial coordinates of the brain of the living subject; acquiring a position of each electrode contact of the at least one electrode in the spatial coordinates of the brain of the living subject; mapping the acquired position of each electrode contact of the at least one electrode in the spatial coordinates of the brain of the living subject onto a corresponding position in the efficacy atlas so as to determine the efficacy of stimulation at the acquired position in the spatial coordinates of the brain of the living subject; and selecting one or more electrode contacts having the highest efficacy for stimulation.
摘要翻译： 一种用于对植入目标区域的深部脑刺激器进行编程以进行最佳刺激的方法，其中所述深部脑刺激器包括至少一个电极，所述至少一个电极具有彼此间隔开的多个电极接触部分， 活体的大脑可以通过一组相应的空间坐标来识别。 在一个实施例中，该方法包括以下步骤：创建效能图谱，其中在活体受试者的脑的目标区域中的位置的任何空间坐标与效能图集中具有对应的图集坐标的位置相关，并且每个位置 在图谱中，效能图集的坐标与在活体大脑的空间坐标的相应位置处的刺激功效相关联; 获取所述至少一个电极在所述活体的大脑的空间坐标中的每个电极接触的位置; 将活体受试者的大脑的空间坐标中的至少一个电极的每个电极接触的获取位置映射到功效图谱中的相应位置，以便确定在所获取的位置处的刺激在空间坐标中的功效 生命主体的大脑; 以及选择具有最高刺激功效的一个或多个电极接触。
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公开(公告)号：US07167760B2
公开(公告)日：2007-01-23
申请号：US10833504
申请日：2004-04-28
IPC分类号： A61N1/05
CPC分类号： A61B90/10 , A61B34/10 , A61N1/3605 , A61N1/36067
摘要： A method of optimal placement of a deep brain stimulator in a targeted region of a brain of a living subject for optimal deep brain stimulation. In one embodiment, the method includes the steps of nonmanually selecting an initial optimal position from, refining the nonmanually selected initial optimal position to determine a final position, and placing the deep brain stimulator at the final position in the targeted region of the brain of the living subject.
摘要翻译： 将深部脑刺激器最佳放置在活体受试者的脑的目标区域中以优化深部脑刺激的方法。 在一个实施例中，该方法包括以下步骤：非手工选择初始最优位置，从精简非手工选择的初始最优位置以确定最终位置，以及将深脑刺激器置于目标区域的最终位置 生活主体
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公开(公告)号：US08152809B1
公开(公告)日：2012-04-10
申请号：US11452513
申请日：2006-06-14
CPC分类号： A61B17/1695 , A61B17/688 , A61B2090/103 , Y10T408/8925
摘要： Described herein is a cranial surgery drill bit having a safety self stopping mechanism for use on bone material to prevent or repair skin erosion and infection which may result from the placement of a cap for holding the lead from Deep Brain Stimulation surgery. The surgical procedure of attaching a lead holding cap onto the bone material of a skull requires an attachment which results in no movement of the lead. Accordingly, counter boring the skull surrounding a pre-existing perforation bore so that the cap is not significantly above the surface of the skull is a technique which allows the cap user to brush hair, etc., without disrupting the attachment and placement of the lead.
摘要翻译： 本文描述的是具有用于骨材料的安全自动停止机构的头颅手术钻头，以防止或修复由深脑刺激手术放置用于保持铅的帽的皮肤侵蚀和感染。 将引线保持帽附接到颅骨的骨骼材料上的外科手术需要附着，这导致引线不会移动。 因此，使围绕预先存在的穿孔的颅骨相对钻孔，使得帽不显着地高于颅骨的表面，这是允许帽用户刷毛等的技术，而不会中断铅的附着和放置 。
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15.发明授权公开(公告)号：US07957808B2
公开(公告)日：2011-06-07
申请号：US11653599
申请日：2007-01-16
IPC分类号： A61N1/18
CPC分类号： A61N1/0534 , A61N1/36082
摘要： A method for programming a deep brain stimulator implanted in a target region of a brain of a living subject. In one embodiment, the method comprises the steps of creating an efficacy atlas; acquiring a position of each electrode contact of the at least one electrode; mapping the acquired position of each electrode contact of the at least one electrode onto a corresponding position in the efficacy atlas so as to determine the efficacy of stimulation at the acquired position; and selecting one or more electrode contacts having the highest efficacy for stimulation.
摘要翻译： 一种用于编程植入生物体脑部的目标区域的深部脑刺激器的方法。 在一个实施例中，该方法包括以下步骤：创建功效图谱; 获取所述至少一个电极的每个电极接触的位置; 将所述至少一个电极的每个电极接触的获取位置映射到所述功效图谱中的相应位置，以便确定所述获得位置处的刺激的功效; 以及选择具有最高刺激功效的一个或多个电极接触。
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公开(公告)号：US20110184306A1
公开(公告)日：2011-07-28
申请号：US13011906
申请日：2011-01-23
申请人： Changqing Chris Kao , Peter E. Konrad , Michael S. Remple , Joseph S. Neimat , P. David Charles
发明人： Changqing Chris Kao , Peter E. Konrad , Michael S. Remple , Joseph S. Neimat , P. David Charles
IPC分类号： A61B5/0476 , A61N1/36
CPC分类号： A61N1/0534 , A61N1/36017 , A61N1/36067
摘要： The invention includes a recordation and stimulation system for determining and delivering an electrical stimulation treatment based upon the current status of neuronal activity of a subject. The system include components for detecting neuronal activity in a subject's brain and, based upon the information received, determine an appropriate electrical stimulation treatment for the subject. The system allows immediate adjustments to the stimulation treatment as the needs of the subject change over time. The invention also includes a method for determining whether a subject has early Parkinson's Disease or advanced Parkinson's Disease. The method includes the steps of acquiring information regarding neuronal discharges in certain areas of the brain, creating a ratio based upon the neuronal activity, and determining whether a previous medical diagnosis of Parkinson's Disease is accurate.
摘要翻译： 本发明包括用于基于受试者的神经元活动的当前状态确定和递送电刺激治疗的记录和刺激系统。 该系统包括用于检测受试者大脑中的神经元活动的组分，并且基于所接收的信息，确定对该受试者的适当的电刺激治疗。 当受试者的需要随着时间的推移而改变时，系统可以立即调整刺激治疗。 本发明还包括用于确定受试者是否具有早期帕金森病或晚期帕金森病的方法。 该方法包括以下步骤：获取有关脑中某些区域的神经元放电的信息，基于神经元活动产生比例，以及确定先前的帕金森氏症的医学诊断是否准确。
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