公开(公告)号：US20200239394A1

公开(公告)日：2020-07-30

申请号：US16636474

申请日：2018-08-10

Applicant: BASF SE

Inventor： Albert WERNER ,  Miriam BRU ROIG ,  Andrei-Nicolae PARVULESCU ,  Roland MINGES ,  Andreas KELLER ,  Stephan MAURER ,  Ulrich MUELLER ,  Wolfgang SIEGEL

IPC: C07C29/80 ,  B01J29/70 ,  B01J37/02 ,  B01J37/08 ,  B01D3/14

Abstract: The present invention relates to a process for recovering 3-methylbut-3-en-1-ol from a feed stream F1 comprising 3-methylbut-3-en-1-ol, one or more solvents, water, and isobutene, wherein 3-methylbut-3-en-1-ol, the one or more solvents and water are separated from isobutene by distillation, the process comprising subjecting the feed stream F1 to distillation conditions in a distillation unit, obtaining a bottoms stream B1 which is enriched in -methylbut-3-en-1-ol, in the one or more solvents and in water compared to the feed stream F1 subjec The present invention relates to a process for recovering 3-methylbut-3-en-1-ol from a feed stream F1 comprising 3-methylbut-3-en-1-ol, one or more solvents, water, and isobutene, wherein 3-methylbut-3-en-1-ol, the one or more solvents and water are separated from isobutene by distillation, the process comprising subjecting the feed stream F1 to distillation conditions in a distillation unit, obtaining a bottoms stream B1 which is enriched in -methylbut-3-en-1-ol, in the one or more solvents and in water compared to the feed stream F1 subjected to distillation conditions, and a top stream T1 which is enriched in isobutene, further subjecting the bottoms stream B1 to distillation conditions in a second distillation unit and obtaining a bottoms stream B2 which is enriched in 3-methylbut-3-en-1-ol compared to the bottoms stream B1 and a top stream T2 which is enriched in water compared to the bottoms stream B1, further subjecting the bottoms stream B2 to distillation conditions in a third distillation unit and obtaining a top stream T3 which is enriched in 3-methylbut-3-en-1-ol compared to the bottoms stream B2 and a bottoms stream B3. ted to distillation conditions, and a top stream T1 which is enriched in isobutene, further subjecting the bot-toms stream B1 to distillation conditions in a second distillation unit and obtaining a bottoms stream B2 which is enriched in 3-methylbut-3-en-1-ol compared to the bottoms stream B1 and a top stream T2 which is enriched in water compared to the bottoms stream B1, further subjecting the bottoms stream B2 to distillation conditions in a third distillation unit and obtaining a top stream T3 which is enriched in 3-methylbut-3-en-1-ol compared to the bottoms stream B2 and a bottoms stream B3.

公开(公告)号：US20180244598A1

公开(公告)日：2018-08-30

申请号：US15964400

申请日：2018-04-27

Applicant: BASF SE

Inventor： Mathias SCHELWIES ,  Rocco PACIELLO ,  Gunnar HEYDRICH ,  Günter WEGNER ,  Gerd-Dieter TEBBEN ,  Martin HAUBNER ,  Andreas KELLER ,  Oliver BEY ,  Stephanie RENZ ,  Georg SEEBER

IPC: C07C45/62 ,  C07C29/17 ,  C07C29/56

CPC classification number: C07C45/62 ,  C07B2200/07 ,  C07C29/172 ,  C07C29/56 ,  C07C2601/14 ,  C07C47/21 ,  C07C47/02 ,  C07C35/12 ,  C07C35/17

Abstract: The present invention relates to a process for the preparation of an optically active carbonyl compound by asymmetric hydrogenation of a prochiral α,β-unsaturated carbonyl compound with hydrogen in the presence of at least one optically active transition metal catalyst that is soluble in the reaction mixture and which has rhodium as catalytically active transition metal and a chiral, bidentate bisphosphine ligand, wherein the reaction mixture during the hydrogenation of the prochiral α,β-unsaturated carbonyl compound additionally comprises at least one compound of the general formula (I): in which R1, R2: are identical or different and are C6- to C10-aryl which is unsubstituted or carries one or more, e.g. 1, 2, 3, 4 or 5, substituents which are selected from C1- to C6-alkyl, C3- to C6-cycloalkyl, C6- to C10-aryl, C1- to C6-alkoxy and amino; Z is a group CHR3R4 or aryl which is unsubstituted or carries one or more, e.g. 1, 2, 3, 4 or 5, substituents which are selected from C1- to C6-alkyl, C3- to C6-cycloalkyl, C6- to C10-aryl, C1- to C6-alkoxy and amino, wherein R3 and R4 are as defined in the claims and the description.

公开(公告)号：US20170066705A1

公开(公告)日：2017-03-09

申请号：US15123325

申请日：2015-03-06

Applicant: BASF SE

Inventor： Volker HICKMANN ,  Stefan RÜDENAUER ,  Martine DEHN ,  Andreas KELLER ,  Stephanie RENZ ,  Daniel SCHNEIDER

IPC: C07C45/51 ,  B01J23/889 ,  C07C49/407

CPC classification number: C07C45/512 ,  A61K8/35 ,  A61K2800/10 ,  A61Q11/00 ,  A61Q19/00 ,  B01J23/8892 ,  C07C45/29 ,  C07C45/298 ,  C07C49/407 ,  C07C2601/14

Abstract: The present invention relates to a process for reacting isopulegol to menthone in the gas phase and to the use of the reaction products thus prepared as additives in foods, cosmetics, pharmaceutical products, tobacco formulations, household products, and laundry care products.

Abstract translation: 本发明涉及在气相中异丙隆与薄荷酮反应的方法以及如此制备的反应产物作为食品，化妆品，药​​物，烟草制剂，家用产品和洗衣护理产品中的添加剂的用途。

公开(公告)号：US20190263738A1

公开(公告)日：2019-08-29

申请号：US16307197

申请日：2017-06-06

Applicant: BASF SE

Inventor： Stephan ZUEND ,  Andreas KELLER ,  Gabriele GRALLA ,  Wolfgang KRAUSE

IPC: C07C29/141 ,  C11B9/00 ,  B01J23/89 ,  B01J37/04 ,  B01J37/06 ,  B01J37/00 ,  B01J37/02

Abstract: The present invention provides a process for preparing an unsaturated alcohol of the formula (I), wherein one of R1 and R2 is preferably C2-C10-alkyl or C2-C10-alkenyl containing one double bond and the other one is preferably hydrogen or methyl; R3 is preferably hydrogen; which comprises subjecting an educt composition including at least 75% by weight of an unsaturated aldehyde of the formula (II) wherein R1, R2 and R3 preferably have the above defined meanings, to a hydrogenation in the presence of a catalyst and a tertiary amine; wherein the tertiary amine is used in an amount ranging from 0.001 to 0.7% by weight, based on the total amount of the liquid reaction mixture. The invention further relates to the nerol compound obtainable by the inventive process, to a fragrance or aroma substance composition comprising the nerol compound obtainable by the inventive process, to a method for imparting and/or intensifying an odor or flavor of a product, and also to perfumed or aromatized products comprising a nerol compound obtainable by the inventive process.

公开(公告)号：US20180230176A1

公开(公告)日：2018-08-16

申请号：US15510268

申请日：2015-09-11

Applicant: BASF SE

Inventor： MICHAEL PUHL ,  Klaus DITRICH ,  Andreas KELLER ,  Pepa DIMITROVA ,  Melanie WEINGARTEN ,  Wolfgang SIEGEL

IPC: C07H15/26 ,  C07H3/06 ,  C07H1/00 ,  A23L33/10

CPC classification number: C07H15/26 ,  A23L33/10 ,  A23V2002/00 ,  C07H1/00 ,  C07H3/06

Abstract: The present invention relates to a method for preparing 2′-O-fucosyllactose, the 2′-O-fucosyllactose obtainable by this method and the use thereof. The method comprises reacting the persilylated, protected fucose derivatives of the formula (I) below, with at least one tri(C1-C6-alkyl)silyl iodide and subsequently reacting the product thus obtained with the compound of the general formula (II), in the presence of a base. In the formulae (I) and (II), the variables are each defined as follows: RSi are the same or different and are a residue of the formula SiRaRbRc; R1 is a C(═O)—R11 residue or an SiR12R13R14 residue, R2 are the same or different and are C1-C8-alkyl or together form a linear C3-C6-alkanediyl, which is unsubstituted or has 1 to 6 methyl groups as substituents; R3 are the same or different and are C1-C8-alkyl or together form a linear C1-C4-alkanediyl, which is unsubstituted or has 1 to 6 methyl groups as substituents.

公开(公告)号：US20180057437A1

公开(公告)日：2018-03-01

申请号：US15536524

申请日：2015-12-18

Applicant: BASF SE

Inventor： Mathias SCHELWIES ,  Rocco PACIELLO ,  Gunnar HEYDRICH ,  Günter WEGNER ,  Gerd TEBBEN ,  Martin HAUBNER ,  Andreas KELLER ,  Oliver BEY ,  Stephanie RENZ ,  Georg SEEBER

IPC: C07C45/62 ,  C07C29/56 ,  C07C29/17

CPC classification number: C07C45/62 ,  C07B2200/07 ,  C07C29/172 ,  C07C29/56 ,  C07C2601/14 ,  C07C47/21 ,  C07C47/02 ,  C07C35/12 ,  C07C35/17

Abstract: The present invention relates to a process for the preparation of an optically active carbonyl compound by asymmetric hydrogenation of a prochiral α,β-unsaturated carbonyl compound with hydrogen in the presence of at least one optically active transition metal catalyst that is soluble in the reaction mixture and which has rhodium as catalytically active transition metal and a chiral, bidentate bisphosphine ligand, wherein the reaction mixture during the hydrogenation of the prochiral α,β-unsaturated carbonyl compound additionally comprises at least one compound of the general formula (I): in which R1, R2: are identical or different and are C6- to C10-aryl which is unsubstituted or carries one or more, e.g. 1, 2, 3, 4 or 5, substituents which are selected from C1- to C6-alkyl, C3- to C6-cycloalkyl, C6- to C10-aryl, C1- to C6-alkoxy and amino; Z is a group CHR3R4 or aryl which is unsubstituted or carries one or more, e.g. 1, 2, 3, 4 or 5, substituents which are selected from C1- to C6-alkyl, C3- to C6-cycloalkyl, C6- to C10-aryl, C1- to C6-alkoxy and amino, wherein R3 and R4 are as defined in the claims and the description.