公开(公告)号：US11486812B2

公开(公告)日：2022-11-01

申请号：US17201700

申请日：2021-03-15

Applicant: Becton, Dickinson and Company

Inventor： Fedor Ilkov ,  Shreyas Bhaban

IPC: G01N15/10 ,  G01J1/44

Abstract: Aspects of the present disclosure include methods for determining a parameter of a photodetector (e.g., a photodetector in a particle analyzer). Methods according to certain embodiments include irradiating a photodetector positioned in a particle analyzer with a light source (e.g., a continuous wave light source) at a first intensity for a first predetermined time interval, irradiating the photodetector with the light source at a second intensity for a second predetermined time interval, integrating data signals from the photodetector over a period of time that includes the first predetermined interval and the second predetermined interval and determining one or more parameters of the photodetector based on the integrated data signals. Systems (e.g., particle analyzers) having light source and a photodetector for practicing the subject methods are also described. Non-transitory computer readable storage medium having instructions stored thereon for determining a parameter of a photodetector according to the subject methods are also provided.

公开(公告)号：US20220074858A1

公开(公告)日：2022-03-10

申请号：US17400741

申请日：2021-08-12

Applicant: Becton, Dickinson and Company

Inventor： Bing Shan ,  Jizuo Zou ,  Svitlana Berezhna ,  Eric D. Diebold ,  An-Dien Nguyen ,  Fedor Ilkov ,  Mark Dorighi

IPC: G01N21/64 ,  G01N15/14 ,  G01J3/44

Abstract: Aspects of the disclosure include systems for irradiating a sample in a flow stream. Systems according to certain embodiments include a light propagator having a first fiber optic operably coupled to a first laser and configured to receive light from the first laser at a proximal end and to convey the laser light from a distal end to a first position on the flow stream and a second fiber optic operably coupled to a second laser and configured to receive light from the second laser at a proximal end and to convey the laser light from a distal end to a second position on the flow stream. Methods for irradiating a sample in a flow stream with the subject systems and detecting light from two or more positions on irradiated flow stream are also provided.

公开(公告)号：US20210325289A1

公开(公告)日：2021-10-21

申请号：US17201700

申请日：2021-03-15

Applicant: Becton, Dickinson and Company

Inventor： Fedor Ilkov ,  Shreyas Bhaban

IPC: G01N15/10

Abstract: Aspects of the present disclosure include methods for determining a parameter of a photodetector (e.g., a photodetector in a particle analyzer). Methods according to certain embodiments include irradiating a photodetector positioned in a particle analyzer with a light source (e.g., a continuous wave light source) at a first intensity for a first predetermined time interval, irradiating the photodetector with the light source at a second intensity for a second predetermined time interval, integrating data signals from the photodetector over a period of time that includes the first predetermined interval and the second predetermined interval and determining one or more parameters of the photodetector based on the integrated data signals. Systems (e.g., particle analyzers) having light source and a photodetector for practicing the subject methods are also described. Non-transitory computer readable storage medium having instructions stored thereon for determining a parameter of a photodetector according to the subject methods are also provided.