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1.发明申请公开(公告)号：US20220074858A1
公开(公告)日：2022-03-10
申请号：US17400741
申请日：2021-08-12
Applicant: Becton, Dickinson and Company
Inventor： Bing Shan , Jizuo Zou , Svitlana Berezhna , Eric D. Diebold , An-Dien Nguyen , Fedor Ilkov , Mark Dorighi
Abstract: Aspects of the disclosure include systems for irradiating a sample in a flow stream. Systems according to certain embodiments include a light propagator having a first fiber optic operably coupled to a first laser and configured to receive light from the first laser at a proximal end and to convey the laser light from a distal end to a first position on the flow stream and a second fiber optic operably coupled to a second laser and configured to receive light from the second laser at a proximal end and to convey the laser light from a distal end to a second position on the flow stream. Methods for irradiating a sample in a flow stream with the subject systems and detecting light from two or more positions on irradiated flow stream are also provided.
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公开(公告)号：US11609176B2
公开(公告)日：2023-03-21
申请号：US17318608
申请日：2021-05-12
Applicant: Becton, Dickinson and Company
Inventor： An-Dien Nguyen , Waheed Amiri , David J. Gianduzzo
Abstract: Methods for evaluating performance a diode laser are provided. In embodiments, methods include receiving a laser beam profile of a diode laser, determining first, second and third laser beam widths at first, second and third laser intensities, respectively, for the laser beam profile, computing a first ratio between the second and third laser beam widths, computing a second ratio between the first and second laser beam widths, evaluating laser performance based on the first and second ratios, and outputting a determination regarding the suitability of the laser for use in a flow cytometry setting. Devices for practicing the subject methods are also provided, and include first and second stages configured to receive a diode laser and beam profiler, respectively. Aspects of the invention further include flow cytometers incorporating a diode laser that has been evaluated by the subject method.
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公开(公告)号：US20220026339A1
公开(公告)日：2022-01-27
申请号：US17318608
申请日：2021-05-12
Applicant: Becton, Dickinson and Company
Inventor： An-Dien Nguyen , Waheed Amiri , David J. Gianduzzo
Abstract: Methods for evaluating performance a diode laser are provided. In embodiments, methods include receiving a laser beam profile of a diode laser, determining first, second and third laser beam widths at first, second and third laser intensities, respectively, for the laser beam profile, computing a first ratio between the second and third laser beam widths, computing a second ratio between the first and second laser beam widths, evaluating laser performance based on the first and second ratios, and outputting a determination regarding the suitability of the laser for use in a flow cytometry setting. Devices for practicing the subject methods are also provided, and include first and second stages configured to receive a diode laser and beam profiler, respectively. Aspects of the invention further include flow cytometers incorporating a diode laser that has been evaluated by the subject method.
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