Abstract:
Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a guide extension catheter. The guide extension catheter may include a push member having a proximal portion with a proximal stiffness, a distal portion with a distal stiffness different from the proximal stiffness, and a transition portion disposed between the proximal portion and the distal portion. The transition portion may provide a smooth transition between the proximal stiffness and the distal stiffness. The push member may have a first outer diameter. A distal tubular member may be attached to the push member. The distal tubular member may have a second outer diameter larger than the first outer diameter.
Abstract:
The disclosure pertains to an intravascular catheter for nerve modulation, comprising an elongate member having a proximal end and a distal end, a balloon having a lumen and a balloon wall, the balloon wall comprising RF permeable sections and non-electrically conductive sections, an electrode disposed within the balloon and extending distally to the furthest distal RF permeable section. The RF permeable sections may comprise a plurality of RF permeable windows, each window having a greater circumferential dimension than an axial dimension. The intravascular system is suited for modulation of renal nerves.
Abstract:
Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a catheter shaft. An expandable member may be coupled to the catheter shaft. The expandable member may be capable of shifting between a folded configuration and an expanded configuration. A plurality of flexible elements may be attached to the expandable member, with a plurality of electrode assemblies disposed on the flexible elements. The flexible elements may have a grooved substrate.
Abstract:
Methods and devices (e.g., for nerve modulation) may include at least one thermistor and a balloon having a balloon wall. In one or more embodiments, the medical device is configured and arranged to transfer heat to the medical device surroundings. In one or more embodiments, the at least one thermistor is a portion of a thermistor array disposed on the balloon wall, the thermistor array including a plurality of thermistors and operatively engaged with a source of electric current. In one or more embodiments, the device includes at least one flexible circuit mounted on the outer surface of the expandable balloon, the at least one flexible circuit including at least one temperature-sensing device that includes at least one thermistor, wherein at least a portion of a conductive layer is electronically coupled to the thermistor, with the proviso that no electrode is associated with the conductive layer.
Abstract:
Systems for the delivery of endoluminal devices are disclosed. An illustrative system may include a delivery sheath having an inner sheath and an outer sheath. The delivery sheath may be configured to restrain a stent in a compressed delivery configuration. The outer sheath may cover the entire length of the stent and the inner sheath may cover a portion of the length of the stent.
Abstract:
A medical device and related methods of use or manufacture are disclosed. The medical device may include an intravascular catheter for nerve modulation. The medical device includes an elongate shaft having a proximal end region, a distal end region, and a lumen extending therebetween. An expandable member is coupled to the distal end region of the elongate shaft. One or more electrical conductors extend from the proximal end region of the elongate shaft to the expandable member. The one or more electrical conductors may have a distal end region secured directly to an outer surface the expandable member. One or more energy delivery regions are positioned on the expandable member and coupled to the one or more electrical conductors.
Abstract:
Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a catheter shaft. An expandable member may be coupled to the catheter shaft. The expandable member may be capable of shifting between a folded configuration and an expanded configuration. A plurality of flexible elements may be attached to the expandable member, with a plurality of electrode assemblies disposed on the flexible elements. The flexible elements may have a grooved substrate.
Abstract:
Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a catheter shaft. An expandable balloon may be coupled to the catheter shaft. The balloon may be capable of shifting between a folded configuration and an expanded configuration. A plurality of elongate electrode assemblies may be disposed on the balloon. A cover layer may be deposited on the electrode assemblies. Portions of the electrode assemblies may be free of the cover layer.
Abstract:
Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a renal nerve modulation device. The renal nerve modulation device may include an elongate shaft. A balloon may be coupled to the shaft. The balloon may have a hydrophilic electrode region. A flexible electrode may be coupled to the shaft and may be disposed within the balloon. The flexible electrode may have a plurality of openings formed therein.
Abstract:
The disclosure pertains to an intravascular catheter, comprising an elongate member having a proximal end and a distal end, a balloon having an interior surface, an exterior surface, a lumen defined by the interior surface and a cylindrical wall extending between the interior surface and the exterior surface, the cylindrical wall having a proximal end and a distal end, the balloon having a plurality of weeping windows disposed in the wall and able to pass an electric current between the interior surface and the exterior surface and wherein the balloon wall is otherwise electrically insulative, and an electrode disposed in the balloon. The intravascular system is suited for modulation of renal nerves, for example.