专利检索 ap:("BRISTOL-MYERS SQUIBB COMPANY") AND inv:"Christine M. TARBY" 第 2 页

11.

发明申请
1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS AND METHODS AND USES THEREFOR 审中-公开

公开(公告)号：US20200038403A1

公开(公告)日：2020-02-06

申请号：US16527802

申请日：2019-07-31

申请人： BRISTOL-MYERS SQUIBB COMPANY

发明人： Yam B. POUDEL , Sanjeev GANGWAR , Liqi HE , Prasanna SIVAPRAKASAM , Matthias BROEKEMA , Matthew COX , Christine M. TARBY , Qian ZHANG

IPC分类号： A61K31/519 , C07D487/04 , A61K39/395 , A61K47/60

摘要： Compounds according to formula I are useful as agonists of Toll-like receptor 7 (TLR7). Such compounds can be used in cancer treatment, especially in combination with an anti-cancer immunotherapy agent, or as a vaccine adjuvant.