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Patent Agency Ranking
11.发明授权公开(公告)号：US09745379B2
公开(公告)日：2017-08-29
申请号：US14949424
申请日：2015-11-23
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Changyu Wang , Nils Lonberg , Alan J. Korman , Mark J. Selby , Mohan Srinivasan , Karla Henning , Michelle Minhua Han , Guodong Chen , Richard Huang , Indrani Chakraborty , Haichun Huang , Susan Wong , Huiming Li
IPC: C07K16/00 , C07H21/00 , C07K16/28 , A61K39/395 , G01N33/68 , G01N33/574 , A61K39/00
CPC classification number: C07K16/2878 , A61K39/3955 , A61K47/48569 , A61K47/6851 , A61K2039/505 , A61K2039/507 , C07K16/2818 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/53 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/74 , C07K2317/75 , C07K2317/76 , C07K2317/92 , G01N33/57492 , G01N33/6872 , G01N2333/70578
Abstract: Provided herein are antibodies, or antigen binding portions thereof, that bind to glucocorticoid-inducible TNF receptor (GITR). Also provided are uses of these proteins in therapeutic applications, such as in the treatment of cancer. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain variable region of the antibodies, and vectors comprising the polynucleotides encoding the heavy and/or light chain variable region of the antibodies.
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12.发明授权Antibodies against glucocorticoid-induced tumor necrosis factor receptor (GITR) and uses thereof 有权抗糖皮质激素诱导的肿瘤坏死因子受体（GITR）的抗体及其用途公开(公告)号：US09228016B2
公开(公告)日：2016-01-05
申请号：US14732082
申请日：2015-06-05
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Changyu Wang , Nils Lonberg , Alan J. Korman , Mark J. Selby , Mohan Srinivasan , Karla Henning , Michelle Minhua Han , Guodong Chen , Richard Huang , Indrani Chakraborty , Haichun Huang , Susan Wong , Huiming Li
IPC: C07K16/00 , C07H21/00 , C07K16/28 , A61K39/395 , G01N33/68 , G01N33/574 , A61K39/00
CPC classification number: C07K16/2878 , A61K39/3955 , A61K47/48569 , A61K47/6851 , A61K2039/505 , A61K2039/507 , C07K16/2818 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/53 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/74 , C07K2317/75 , C07K2317/76 , C07K2317/92 , G01N33/57492 , G01N33/6872 , G01N2333/70578
Abstract: Provided herein are antibodies, or antigen binding portions thereof, that bind to glucocorticoid-inducible TNF receptor (GITR). Also provided are uses of these proteins in therapeutic applications, such as in the treatment of cancer. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain variable region of the antibodies, and vectors comprising the polynucleotides encoding the heavy and/or light chain variable region of the antibodies.
Abstract translation: 本文提供了结合糖皮质激素诱导型TNF受体（GITR）的抗体或其抗原结合部分。 还提供了这些蛋白质在治疗应用中的用途，例如在癌症的治疗中。 还提供了产生抗体的细胞，编码抗体的重链和/或轻链可变区的多核苷酸，以及包含编码抗体的重链和/或轻链可变区的多核苷酸的载体。
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公开(公告)号：US20240132622A1
公开(公告)日：2024-04-25
申请号：US18357007
申请日：2023-07-20
Applicant: Bristol-Myers Squibb Company
Inventor： Lin Hui Su , Ekaterina Deyanova , Burce Ergel Gurbuzbalaban , Mariana Nacht , Samantha Elaine Pace , Yun Wang , Qing Xiao , Ramakrishna Chandran , Shailesh Dudhgaonkar , Michael Louis Doyle , Michael Gilman , Richard Huang , Akbar Nayeem , Alok Sharma , Qihong Zhao
CPC classification number: C07K16/40 , A01N1/0226 , A61K45/06 , A61K47/6871 , A61K49/0002 , A61P19/02 , A61P37/06
Abstract: The present application relates to particular anti-PAD4 (peptidyl arginine deiminase 4) antibodies, nucleic acids encoding the antibodies, vectors and host cells comprising the nucleic acids, and methods of making and using the antibodies.
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公开(公告)号：US20180298097A1
公开(公告)日：2018-10-18
申请号：US16017489
申请日：2018-06-25
Applicant: Bristol-Myers Squibb Company
Inventor： Xiao Min Schebye , Mark J. Selby , Michelle Minhua Han , Christine Bee , Andy X. Deng , Anan Chuntharapai , Brigitte Devaux , Huiming Li , Paul O. Sheppard , Alan J. Korman , Daniel F,. Ardourel , Ekaterina Deyanova , Richard Huang , Guodong Chen , Michelle Kuhne , Hong-An Troung
Abstract: Provided herein are antibodies, or antigen-binding portions thereof, that bind to T-cell immunoglobulin and mucin-domain containing-3 (TIM3) protein. Also provided are uses of these antibodies, or antigen-binding portions thereof, in therapeutic applications, such as treatment of cancer. Further provided are cells that produce the antibodies, or antigen-binding portions thereof, polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen-binding portions thereof, and vectors comprising the polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen-binding portions thereof.
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公开(公告)号：US10077306B2
公开(公告)日：2018-09-18
申请号：US15649380
申请日：2017-07-13
Applicant: Bristol-Myers Squibb Company
Inventor： Xiao Min Schebye , Mark J. Selby , Michelle Minhua Han , Christine Bee , Andy X. Deng , Anan Chuntharapai , Brigitte Devaux , Huiming Li , Paul O. Sheppard , Alan J. Korman , Daniel F. Ardourel , Ekaterina Deyanova , Richard Huang , Guodong Chen , Michelle Kuhne , Hong-An Troung
CPC classification number: C07K16/2803 , A61K47/6849 , A61K2039/505 , A61K2039/507 , A61P35/00 , C07K16/2818 , C07K16/2827 , C07K16/2878 , C07K16/30 , C07K16/3046 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/41 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/71 , C07K2317/732 , C07K2317/734 , C07K2317/74 , C07K2317/76 , C07K2317/92 , C07K2317/94 , G01N33/57492
Abstract: Provided herein are antibodies, or antigen-binding portions thereof, that bind to T-cell immunoglobulin and mucin-domain containing-3 (TIM3) protein. Also provided are uses of these antibodies, or antigen-binding portions thereof, in therapeutic applications, such as treatment of cancer. Further provided are cells that produce the antibodies, or antigen-binding portions thereof, polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen-binding portions thereof, and vectors comprising the polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen-binding portions thereof.
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