公开(公告)号：US20130144174A1

公开(公告)日：2013-06-06

申请号：US13674639

申请日：2012-11-12

申请人： John D. Hatlestad ,  Binh C Tran ,  Bin Mi ,  Ronald W. Heil, Jr.

发明人： John D. Hatlestad ,  Binh C Tran ,  Bin Mi ,  Ronald W. Heil, Jr.

IPC分类号： A61B5/0205 ,  A61B5/03 ,  A61B5/20

CPC分类号： A61B5/0205 ,  A61B5/0028 ,  A61B5/0031 ,  A61B5/03 ,  A61B5/036 ,  A61B5/201 ,  A61B5/416 ,  A61B5/6846

摘要： An implantable system for ambulatory monitoring of a high-risk heart failure patient includes a first pressure sensor implantable within an abdomen of the patient for sensing and generating an output representative of a baseline intra-abdominal pressure value of the patient and for chronically sensing and generating an output representative of an intra-abdominal pressure value of the patient at periodic intervals. At least one second implantable sensor is provided for sensing and generating an output representative of a second physiological parameter of the patient. Additionally, the system includes a processor for correlating the output of the first pressure sensor and the second physiologic sensor, and for comparing differences between the baseline intra-abdominal pressure value and subsequent intra-abdominal pressure values. The processor can reside in another implantable device or in an external device/system.

摘要翻译： 用于高风险心力衰竭患者的动态监测的可植入系统包括可植入患者腹部的第一压力传感器，用于感测和产生代表患者的基线腹内压力值的输出，并且用于长期感测和产生 以周期性间隔代表患者的腹内压力值的输出。 提供至少一个第二可植入传感器用于感测和产生代表患者的第二生理参数的输出。 另外，该系统包括用于将第一压力传感器和第二生理传感器的输出相关联并且用于比较基线腹内压力值和随后的腹内压力值之间的差异的处理器。 处理器可以驻留在另一个可植入设备中或外部设备/系统中。

公开(公告)号：US20110190669A1

公开(公告)日：2011-08-04

申请号：US13082954

申请日：2011-04-08

申请人： Bin Mi ,  Abhijeet V. Chavan ,  Keith R. Maile

发明人： Bin Mi ,  Abhijeet V. Chavan ,  Keith R. Maile

IPC分类号： A61N7/00

CPC分类号： A61N1/37288 ,  A61B5/0028 ,  A61N1/37217

摘要： Implantable medical devices including an ultrasonic transducer and methods of optimizing an ultrasonic transducer of an implantable medical device are disclosed. The implantable medical device can include a housing, an ultrasonic transducer disposed within an interior of the housing, and a limiting structure configured to constrain deformation of the ultrasonic transducer. The limiting structure can include a separate structure coupled to the housing, or can comprise a resonant portion of the housing itself. During operation, the ultrasonic transducer is configured to communicate at a frequency at or near a resonant frequency of the housing.

摘要翻译： 公开了包括超声换能器和优化可植入医疗装置的超声换能器的方法的可植入医疗装置。 可植入医疗装置可以包括壳体，设置在壳体内部的超声波换能器以及限制超声换能器变形的限制结构。 限制结构可以包括耦合到壳体的单独结构，或者可以包括壳体本身的谐振部分。 在操作期间，超声波换能器被配置为在壳体的谐振频率处或接近谐振频率处的频率进行通信。

公开(公告)号：US20100317978A1

公开(公告)日：2010-12-16

申请号：US12774990

申请日：2010-05-06

申请人： Keith R. Maile ,  Abhijeet V. Chavan ,  Thomas W. Piaget ,  Bin Mi

发明人： Keith R. Maile ,  Abhijeet V. Chavan ,  Thomas W. Piaget ,  Bin Mi

IPC分类号： A61B5/0215 ,  A61B5/00 ,  A61B5/03 ,  H02N2/18

CPC分类号： H01L41/1138 ,  A61B5/0031 ,  A61B5/0215 ,  H02N2/18

摘要： Methods, systems, and apparatus for powering and/or recharging medical devices implanted within the body are described. An illustrative implantable sensor for sensing one or more physiologic parameters within a body lumen includes a housing having an exterior wall that has an inner surface and an outer surface and that defines an internal cavity. A portion of the housing includes an electrically conductive material that functions as a first electrical conductor. A flexible piezoelectric layer is disposed adjacent to a portion of the exterior wall and a second electrical conductor is disposed adjacent to the piezoelectric layer. The piezoelectric layer is configured to displace in response to periodic pressure pulses within the body lumen and generate a voltage differential between the first and second electrical conductors.

摘要翻译： 描述了植入体内的医疗装置的供电和/或再充电的方法，系统和装置。 用于感测体腔内的一个或多个生理参数的说明性可植入传感器包括具有外壁的壳体，所述外壁具有内表面和外表面，并且限定内腔。 壳体的一部分包括用作第一电导体的导电材料。 柔性压电层设置成与外壁的一部分相邻，并且第二电导体邻近压电层设置。 压电层被配置为响应于体腔内的周期性压力脉冲而移位，并在第一和第二电导体之间产生电压差。

公开(公告)号：US20080021509A1

公开(公告)日：2008-01-24

申请号：US11780992

申请日：2007-07-20

申请人： Bin Mi ,  Abhijeet V. Chavan ,  Keith R. Maile

发明人： Bin Mi ,  Abhijeet V. Chavan ,  Keith R. Maile

IPC分类号： A61N1/02

CPC分类号： A61N1/37288 ,  A61B5/0028 ,  A61N1/37217

摘要： An implantable medical device comprising a housing and an ultrasonic transducer having a communication frequency coupled to a portion of the housing. The housing resonates at the communication frequency, and a casing is coupled to the housing and disposed over the ultrasonic transducer. The casing is adapted to amplify the deformation of the ultrasonic transducer in a bending mode and transfer the bending moment to the housing. An implantable medical device comprising a housing having an upper portion and a lower portion. A first ultrasonic transducer is coupled to a first connection rod and is coaxial with the first connection rod. The first ultrasonic transducer and first connection rod are interposed between the upper and lower portions such that the first ultrasonic transducer is adapted to vibrate the upper and lower portions simultaneously. A method of optimizing an ultrasonic transducer and a housing of an implantable medical device.

摘要翻译： 一种可植入医疗装置，包括壳体和具有耦合到壳体的一部分的通信频率的超声换能器。 壳体以通信频率谐振，并且壳体耦合到壳体并且设置在超声换能器上。 壳体适于在弯曲模式下放大超声波换能器的变形，并将弯矩转移到壳体。 一种可植入医疗装置，包括具有上部和下部的壳体。 第一超声换能器联接到第一连接杆并且与第一连接杆同轴。 第一超声波换能器和第一连接杆插入在上部和下部之间，使得第一超声波换能器适于同时振动上部和下部。 一种优化超声换能器和可植入医疗装置的壳体的方法。

公开(公告)号：US08301262B2

公开(公告)日：2012-10-30

申请号：US12357460

申请日：2009-01-22

申请人： Bin Mi ,  Abhijeet V. Chavan ,  Keith R. Maile

发明人： Bin Mi ,  Abhijeet V. Chavan ,  Keith R. Maile

IPC分类号： A61N1/00

CPC分类号： A61N1/37211 ,  A61B5/0031 ,  A61B5/01 ,  A61B5/0215 ,  A61B5/026 ,  A61N1/08 ,  A61N1/37217

摘要： Systems and methods for communicating with or powering implantable medical devices using a direct inductive/acoustic telemetry link are disclosed. An illustrative system includes an interrogator device located outside of the patient's body, an implantable medical device including an energy translator circuit adapted to convert inductive or RF signals received from the interrogator device into an acoustic signal for driving an acoustic transducer, and a remote device adapted to sense one or more parameters within the body.

摘要翻译： 公开了使用直接感应/声学遥测链路与可植入医疗装置通信或供电的系统和方法。 说明性系统包括位于患者身体外部的询问器装置，可植入医疗装置，其包括能量转换器电路，其适于将从询问器装置接收的感应或RF信号转换成用于驱动声换能器的声信号，以及适配器 感测身体内的一个或多个参数。

公开(公告)号：US08548592B2

公开(公告)日：2013-10-01

申请号：US13082954

申请日：2011-04-08

申请人： Bin Mi ,  Abhijeet V. Chavan ,  Keith R. Maile

发明人： Bin Mi ,  Abhijeet V. Chavan ,  Keith R. Maile

IPC分类号： A61N1/375

CPC分类号： A61N1/37288 ,  A61B5/0028 ,  A61N1/37217

摘要： Implantable medical devices including an ultrasonic transducer and methods of optimizing an ultrasonic transducer of an implantable medical device are disclosed. The implantable medical device can include a housing, an ultrasonic transducer disposed within an interior of the housing, and a limiting structure configured to constrain deformation of the ultrasonic transducer. The limiting structure can include a separate structure coupled to the housing, or can comprise a resonant portion of the housing itself. During operation, the ultrasonic transducer is configured to communicate at a frequency at or near a resonant frequency of the housing.

摘要翻译： 公开了包括超声换能器和优化可植入医疗装置的超声换能器的方法的可植入医疗装置。 可植入医疗装置可以包括壳体，设置在壳体内部的超声波换能器以及限制超声换能器变形的限制结构。 限制结构可以包括耦合到壳体的单独结构，或者可以包括壳体本身的谐振部分。 在操作期间，超声波换能器被配置为在壳体的谐振频率处或接近谐振频率处的频率进行通信。

公开(公告)号：US20090198307A1

公开(公告)日：2009-08-06

申请号：US12357460

申请日：2009-01-22

申请人： Bin Mi ,  Abhijeet V. Chavan ,  Keith R. Maile

发明人： Bin Mi ,  Abhijeet V. Chavan ,  Keith R. Maile

IPC分类号： A61N1/08 ,  A61B5/07

CPC分类号： A61N1/37211 ,  A61B5/0031 ,  A61B5/01 ,  A61B5/0215 ,  A61B5/026 ,  A61N1/08 ,  A61N1/37217

摘要： Systems and methods for communicating with or powering implantable medical devices using a direct inductive/acoustic telemetry link are disclosed. An illustrative system includes an interrogator device located outside of the patient's body, an implantable medical device including an energy translator circuit adapted to convert inductive or RF signals received from the interrogator device into an acoustic signal for driving an acoustic transducer, and a remote device adapted to sense one or more parameters within the body.

摘要翻译： 公开了使用直接感应/声学遥测链路与可植入医疗装置通信或供电的系统和方法。 说明性系统包括位于患者身体外部的询问器装置，可植入医疗装置，其包括能量转换器电路，其适于将从询问器装置接收的感应或RF信号转换成用于驱动声换能器的声信号，以及适配器 感测身体内的一个或多个参数。

公开(公告)号：US08777863B2

公开(公告)日：2014-07-15

申请号：US12774976

申请日：2010-05-06

申请人： Thomas W. Piaget ,  Bin Mi ,  Lance E. Juffer ,  Keith R. Maile ,  Abhijeet V. Chavan ,  Cheng Zhang

发明人： Thomas W. Piaget ,  Bin Mi ,  Lance E. Juffer ,  Keith R. Maile ,  Abhijeet V. Chavan ,  Cheng Zhang

IPC分类号： A61B5/02

CPC分类号： H01L41/1138 ,  A61B5/0031 ,  A61B5/0215 ,  H02N2/18

摘要： Methods, systems, and apparatus for powering and/or recharging medical devices implanted within the body are described. An illustrative power generation module disposable within the interior space of an implantable medical device includes a module body that defines an interior cavity as well as a flexible diaphragm that spans the interior cavity. The flexible diaphragm includes a first electrical conductor, a piezoelectric layer disposed adjacent to the first electrical conductor, and a second electrical conductor disposed adjacent to the piezoelectric layer. The piezoelectric layer is configured to displace within the interior cavity and generate a voltage differential between the first electrical conductor and the second electrical conductor.

摘要翻译： 描述了植入体内的医疗装置的供电和/或再充电的方法，系统和装置。 在可植入医疗装置的内部空间内可放置的说明性发电模块包括限定内腔的模块主体以及跨越内腔的柔性隔膜。 柔性隔膜包括第一电导体，邻近第一电导体设置的压电层和邻近压电层设置的第二电导体。 压电层被配置为在内腔内移位，并在第一电导体和第二电导体之间产生电压差。

公开(公告)号：US08506495B2

公开(公告)日：2013-08-13

申请号：US12774983

申请日：2010-05-06

申请人： Bin Mi ,  Lance E. Juffer ,  Keith R. Maile ,  Abhijeet V. Chavan ,  Thomas W. Piaget

发明人： Bin Mi ,  Lance E. Juffer ,  Keith R. Maile ,  Abhijeet V. Chavan ,  Thomas W. Piaget

IPC分类号： A61B5/02

CPC分类号： A61N1/36564 ,  A61B5/0031 ,  A61B5/0215 ,  A61N1/37205 ,  A61N1/37217 ,  A61N1/37288 ,  A61N1/375

摘要： Methods, systems, and apparatus for powering and/or recharging medical devices implanted within the body are described. An illustrative implantable medical device includes a housing having an internal cavity and a flexible anchor assembly that is coupled to the housing. The flexible anchor assembly includes a first electrical conductor, a second electrical conductor, and a piezoelectric layer that is disposed between the first and second electrical conductors and that is configured to displace in response to a physiologic force applied to the flexible anchor assembly and generate a voltage differential between the first and second electrical conductors. The implantable medical device includes power circuitry that converts the voltage differential between the first and second electrical conductors into an operating current for powering one or more components within the implantable medical device and/or for recharging a rechargeable power supply within the device.

摘要翻译： 描述了植入体内的医疗装置的供电和/或再充电的方法，系统和装置。 示例性可植入医疗装置包括具有内腔的壳体和联接到壳体的柔性锚固组件。 柔性锚固组件包括第一电导体，第二电导体和压电层，其被设置在第一和第二电导体之间，并被配置为响应于施加到柔性锚固组件的生理力而移位并产生 第一和第二电导体之间的电压差。 可植入医疗装置包括电力电路，其将第一和第二电导体之间的电压差转换成用于为可植入医疗装置内的一个或多个部件供电的动作电流和/或用于为装置内的可再充电电源再充电。

公开(公告)号：US07949396B2

公开(公告)日：2011-05-24

申请号：US11780992

申请日：2007-07-20

申请人： Bin Mi ,  Abhijeet V. Chavan ,  Keith R. Maile

发明人： Bin Mi ,  Abhijeet V. Chavan ,  Keith R. Maile

IPC分类号： A61N1/375

CPC分类号： A61N1/37288 ,  A61B5/0028 ,  A61N1/37217

摘要： An implantable medical device comprising a housing and an ultrasonic transducer having a communication frequency coupled to a portion of the housing. The housing resonates at the communication frequency, and a casing is coupled to the housing and disposed over the ultrasonic transducer. The casing is adapted to amplify the deformation of the ultrasonic transducer in a bending mode and transfer the bending moment to the housing. An implantable medical device comprising a housing having an upper portion and a lower portion. A first ultrasonic transducer is coupled to a first connection rod and is coaxial with the first connection rod. The first ultrasonic transducer and first connection rod are interposed between the upper and lower portions such that the first ultrasonic transducer is adapted to vibrate the upper and lower portions simultaneously. A method of optimizing an ultrasonic transducer and a housing of an implantable medical device.

摘要翻译： 一种可植入医疗装置，包括壳体和具有耦合到壳体的一部分的通信频率的超声换能器。 壳体以通信频率谐振，并且壳体耦合到壳体并且设置在超声换能器上。 壳体适于在弯曲模式下放大超声波换能器的变形，并将弯矩转移到壳体。 一种可植入医疗装置，包括具有上部和下部的壳体。 第一超声换能器联接到第一连接杆并且与第一连接杆同轴。 第一超声波换能器和第一连接杆插入在上部和下部之间，使得第一超声波换能器适于同时振动上部和下部。 一种优化超声换能器和可植入医疗装置的壳体的方法。