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公开(公告)号:US11090227B2
公开(公告)日:2021-08-17
申请号:US15996291
申请日:2018-06-01
Applicant: BIO-RAD LABORATORIES, INC.
Inventor: Alireza Ebrahim , Karl De Vore , John Sass
Abstract: Methods and devices for transferring materials between containers are discussed. One such connector includes: a base; a first elongate structure having first and second ends, the first elongate structure extending from a first side of the base at the first end to the second end distal the base, the second end forming a first opening sized and configured to receive a first container; a duct extending through the base and having a first tip skirted on one or more sides by the first elongate structure; a first guard positioned within the first elongate structure, wherein the first guard comprises a first surface, and the first surface is located further away from the base than the first tip. When the first container is moved into the first opening, the first surface moves toward the base, and the first tip enters the first container, creating a fluid path for the first container.
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公开(公告)号:US20180203023A1
公开(公告)日:2018-07-19
申请号:US15849514
申请日:2017-12-20
Applicant: Bio-Rad Laboratories, Inc.
Inventor: Alireza Ebrahim , Karl De Vore , Christopher Spates
Abstract: Methods are provided for end users of diagnostic measurement procedures to prepare quality controls having desired analyte recoveries, estimate recoveries of quality controls already prepared, and compare estimated and measured recoveries. To prepare a quality control containing a particular analyte, a desired recovery of a measurement procedure for the analyte can be scaled by a correlation factor to obtain a target nominal concentration of the analyte in the quality control. Alternatively, the nominal concentration of an analyte in a quality control can be scaled by a correlation factor to obtain a predicted recovery of a measurement procedure for the analyte. The correlation factors can be based on recovery data previously obtained using the measurement procedure and optionally one or more reference procedures, and can be calculated using regression analysis of these data. Each quality control can be prepared by dissolving a number of solid beads containing the analyte(s) of interest in a volume of base matrix.
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公开(公告)号:US20170131302A1
公开(公告)日:2017-05-11
申请号:US15411775
申请日:2017-01-20
Applicant: Bio-Rad Laboratories, Inc.
Inventor: Alireza Ebrahim , Karl De Vore , Christopher Spates
IPC: G01N33/96
Abstract: Provided herein are assay control materials comprising stable analytes and lyophilized unstable analytes, and methods of making and using the same.
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公开(公告)号:US09909959B2
公开(公告)日:2018-03-06
申请号:US15296901
申请日:2016-10-18
Applicant: Bio-Rad Laboratories, Inc.
Inventor: Alireza Ebrahim , Christopher Spates , Karl De Vore
CPC classification number: G01N1/28 , C12Q1/32 , G01N21/91 , G01N33/96 , G01N2001/2893 , G01N2333/765 , G01N2496/00 , G01N2496/80
Abstract: Solid beads each containing a selected quantity of analyte are combined and a liquid base matrix that contains attributes of a biological fluid that is to be assayed, together constitute a kit from which a laboratory technician can, at the point of use, prepare a liquid control for a particular analyte, and preferably a series of such controls at different levels of the same analyte customized for a particular assay.
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15.
公开(公告)号:US09506939B2
公开(公告)日:2016-11-29
申请号:US14270701
申请日:2014-05-06
Applicant: Bio-Rad Laboratories, Inc.
Inventor: Alireza Ebrahim , Karl De Vore , Christopher Spates
CPC classification number: G01N33/96 , F26B5/06 , G01N2496/80
Abstract: Provided herein are assay control materials comprising stable analytes and lyophilized unstable analytes, and methods of making and using the same.
Abstract translation: 本文提供了包含稳定分析物和冻干不稳定分析物的测定对照材料及其制备和使用方法。
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公开(公告)号:US20160061694A1
公开(公告)日:2016-03-03
申请号:US14938780
申请日:2015-11-11
Applicant: Bio-Rad Laboratories, Inc. QSD
Inventor: Alireza Ebrahim , Christopher Spates , Karl De Vore
CPC classification number: G01N1/28 , C12Q1/32 , G01N21/91 , G01N33/96 , G01N2001/2893 , G01N2333/765 , G01N2496/00 , G01N2496/80
Abstract: Solid beads each containing a selected quantity of analyte are combined and a liquid base matrix that contains attributes of a biological fluid that is to be assayed, together constitute a kit from which a laboratory technician can, at the point of use, prepare a liquid control for a particular analyte, and preferably a series of such controls at different levels of the same analyte customized for a particular assay.
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17.
公开(公告)号:US20140329263A1
公开(公告)日:2014-11-06
申请号:US14270701
申请日:2014-05-06
Applicant: Bio-Rad Laboratories, Inc.
Inventor: Alireza Ebrahim , Karl De Vore , Christopher Spates
CPC classification number: G01N33/96 , F26B5/06 , G01N2496/80
Abstract: Provided herein are assay control materials comprising stable analytes and lyophilized unstable analytes, and methods of making and using the same.
Abstract translation: 本文提供了包含稳定分析物和冻干不稳定分析物的测定对照材料及其制备和使用方法。
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