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公开(公告)号：US20160051984A1
公开(公告)日：2016-02-25
申请号：US14834870
申请日：2015-08-25
IPC分类号： B01L3/00
CPC分类号： F16K11/065 , B01L3/502738 , B01L2300/0636 , B01L2300/0816 , B01L2300/123 , B01L2400/06 , B01L2400/0655 , B01L2400/0661 , B01L2400/082 , F16K7/16 , F16K11/161 , F16K27/003 , F16K31/52483 , F16K99/0001 , F16K99/0015 , F16K99/0042 , F16K2099/008 , F16K2099/0084 , G01N35/1097 , G01N2035/00158 , G01N2035/00237 , Y10T137/0396 , Y10T137/86445 , Y10T137/86919 , Y10T137/87
摘要： An array of valves are arranged in n columns and m lines and which are each designed to control a fluid flow in an associated flow channel in a lab-on-a-chip system. The array includes at least two valves, every column having not more than one valve and every line having from zero to n valves. A device is used for actuating the valves. The valves are pressure-actuated. To produce the device, the flow channels are arranged in accordance with the arrangement of the valves. Which valves are actuated being changeable by movement of projections relative to array of valves so as to change which valves the projections are pressed against.
摘要翻译： 一组阀门以n列和m行排列，并且每个都被设计成控制在芯片实验室系统中相关联的流动通道中的流体流动。 该阵列包括至少两个阀，每列具有不超过一个阀，并且每一行具有从零到n的阀。 一个装置用于致动阀门。 阀是压力驱动的。 为了生产该装置，流动通道根据阀的布置被布置。 通过相对于阀阵列的突起的移动来改变哪些阀被改变，以便改变突起被压住的哪个阀。
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公开(公告)号：US20160025667A1
公开(公告)日：2016-01-28
申请号：US14807035
申请日：2015-07-23
CPC分类号： G01N27/27 , G01N15/04 , G01N27/30 , G01N27/40 , G01N33/50 , G01N33/566 , Y10T436/143333
摘要： An apparatus for detecting liquids or substances from liquids in spatially separate reaction zones using a plug-in module or a chip card for rapid immunological tests, for example, with the help of a reading device. The liquids or substances from liquids are detected by a sensor array and on which at least one diaphragm is arranged. Individual sensors are spatially separated from each other on a plane by means of walls. The diaphragm is filled with liquid that is to be analyzed. Sealed reaction chambers are created when pressure is applied to the diaphragm. Pores in the diaphragm are completely closed in the zone of the walls while the pores are merely reduced in size and liquid can continue to be exchanged in zones directly above the sensors. No liquid can be exchanged between adjacent reaction chambers as long as pressure is applied to and compresses the diaphragm.
摘要翻译： 借助于读取装置，使用插件模块或用于快速免疫测试的芯片卡在空间分离的反应区域中检测来自液体的液体或物质的装置。 来自液体的液体或物质由传感器阵列检测并且至少设有一个隔膜。 单个传感器在空间上通过壁在空间上彼此分开。 隔膜充满待分析的液体。 当对隔膜施加压力时，产生密封的反应室。 隔膜中的孔隙在壁的区域中完全封闭，而孔仅尺寸减小，并且液体可以在传感器正上方的区域中继续更换。 只要施加压力并压缩隔膜，相邻反应室之间就不能更换液体。
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公开(公告)号：US20140294674A1
公开(公告)日：2014-10-02
申请号：US14306401
申请日：2014-06-17
发明人： Walter Gumbrecht , Manfred Stanzel
IPC分类号： G01N33/543
CPC分类号： C12M1/34 , G01N27/026 , G01N33/5438
摘要： A biochip includes a flat carrier and an array of spots containing catcher molecules which are arranged on the carrier. Each spot is associated with a microelectrode arrangement for impedance spectroscopic detection of binding events occurring between the catcher molecules and the target molecules applied via an analyte solution. In order to increase the sensitivity or the binding-specific measuring effects of the bio-chip, the electrode arrangement is at least partially embedded in a hydrophilic reaction layer containing catcher molecules and which is permeable to target molecules.
摘要翻译： 生物芯片包括平坦载体和布置在载体上的含有捕获剂分子的斑点阵列。 每个点与微电极布置相关联，用于阻抗光谱检测在捕获剂分子与通过分析物溶液施加的靶分子之间发生的结合事件。 为了提高生物芯片的灵敏度或结合特异性的测量效果，电极布置至少部分地嵌入含有捕获剂分子的亲水反应层中，并且其对靶分子是可渗透的。
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