公开(公告)号：US20210251890A1

公开(公告)日：2021-08-19

申请号：US17177894

申请日：2021-02-17

Applicant: Boston Scientific Scimed, Inc.

Inventor： Jessica L. Grimsby ,  Lauren Lydecker ,  Gerald Fredrickson

IPC: A61K9/00 ,  A61K31/722 ,  A61K45/06 ,  A61K9/14 ,  A61K47/02

Abstract: Compositions and related kits and methods for treating a target site of a patient are described herein. The composition may include a hemostatic agent and a pH agent, for example. Methods of treatment include delivering and applying the hemostatic agent and the pH agent to a gastrointestinal system of a patient via a medical device to reduce bleeding of tissue in the gastrointestinal system.

公开(公告)号：US20210060211A1

公开(公告)日：2021-03-04

申请号：US16999856

申请日：2020-08-21

Applicant: Boston Scientific Scimed Inc.

Inventor： Lauren Lydecker ,  Jennifer Whelehan

IPC: A61L27/52 ,  A61L27/58 ,  C08L101/00 ,  C08J3/24 ,  C08L5/08

Abstract: In accordance with some aspects, the present disclosure is directed to medical compositions that comprises (a) a first hydrophilic polymer functionalized with a plurality of first functional groups and (b) a second hydrophilic polymer functionalized with a plurality of second functional groups, wherein the first and second functional groups are selected to react and form covalent bonds upon a change in conditions such that the first and second hydrophilic polymers crosslink with one another. In other aspects the present disclosure is directed to kits that comprise such medical compositions and to medical procedures that utilize such medical compositions.

公开(公告)号：US12083216B2

公开(公告)日：2024-09-10

申请号：US17177894

申请日：2021-02-17

Applicant: Boston Scientific Scimed, Inc.

Inventor： Jessica L. Grimsby ,  Lauren Lydecker ,  Gerald Fredrickson

IPC: A61K9/00 ,  A61K9/14 ,  A61K31/722 ,  A61K45/06 ,  A61K47/02

CPC classification number: A61K9/0024 ,  A61K9/14 ,  A61K31/722 ,  A61K45/06 ,  A61K47/02

Abstract: Compositions and related kits and methods for treating a target site of a patient are described herein. The composition may include a hemostatic agent and a pH agent, for example. Methods of treatment include delivering and applying the hemostatic agent and the pH agent to a gastrointestinal system of a patient via a medical device to reduce bleeding of tissue in the gastrointestinal system.

公开(公告)号：US12064535B2

公开(公告)日：2024-08-20

申请号：US17184713

申请日：2021-02-25

Applicant: Boston Scientific Scimed, Inc.

Inventor： Martin Burke ,  Daniel Tuck ,  John T. Favreau ,  Lauren Lydecker

IPC: A61L31/14 ,  A61L31/04 ,  A61L31/12 ,  A61L31/16 ,  B33Y70/00 ,  B33Y80/00

CPC classification number: A61L31/146 ,  A61L31/041 ,  A61L31/125 ,  A61L31/16 ,  B33Y70/00 ,  B33Y80/00 ,  A61L2300/406 ,  A61L2300/414 ,  A61L2400/12

Abstract: A medical system including a tube defining a lumen, a porous body connected to a distal end of the tube to be advanced to a target site within a subject. The porous body defines a plurality of openings, the plurality of openings are in fluid connection with the lumen, the porous body includes a first material and a second material, and the second material elutes from the porous body in the subject.

公开(公告)号：US11986175B2

公开(公告)日：2024-05-21

申请号：US17095276

申请日：2020-11-11

Applicant: Boston Scientific Scimed, Inc.

Inventor： Gerald Fredrickson ,  Jennifer Whelehan ,  Matthew Laplaca ,  Lauren Lydecker

IPC: A61B17/00 ,  A61M5/31 ,  A61M5/315 ,  A61M25/00

CPC classification number: A61B17/00491 ,  A61M5/3129 ,  A61M5/315 ,  A61M25/0026 ,  A61M25/0068 ,  A61B2017/00495 ,  A61M2025/0037 ,  A61M2025/0039 ,  A61M2202/02 ,  A61M2202/04 ,  A61M2202/064 ,  A61M2210/1042

Abstract: A medical system includes a propellant source containing a propellant fluid, containers containing a material, and a shaft having a plurality of lumens, each of the plurality of lumens having a first opening at a proximal end of the shaft and a second opening at a distal end of the shaft. The plurality of lumens are fluidly coupled to one or more of the propellant source and at least one of the plurality of containers, and a first lumen surrounds, is coaxial with, or is side-by-side with, at least one other lumen.

公开(公告)号：US20240108789A1

公开(公告)日：2024-04-04

申请号：US18539045

申请日：2023-12-13

Applicant: Boston Scientific Scimed, Inc.

Inventor： Lauren Lydecker ,  Jennifer Whelehan

IPC: A61L27/52 ,  A61L27/58 ,  C08J3/24 ,  C08L5/08 ,  C08L101/00

CPC classification number: A61L27/52 ,  A61L27/58 ,  C08J3/24 ,  C08L5/08 ,  C08L101/005

Abstract: In accordance with some aspects, the present disclosure is directed to medical compositions that comprises (a) a first hydrophilic polymer functionalized with a plurality of first functional groups and (b) a second hydrophilic polymer functionalized with a plurality of second functional groups, wherein the first and second functional groups are selected to react and form covalent bonds upon a change in conditions such that the first and second hydrophilic polymers crosslink with one another. In other aspects the present disclosure is directed to kits that comprise such medical compositions and to medical procedures that utilize such medical compositions.

公开(公告)号：US20210259691A1

公开(公告)日：2021-08-26

申请号：US17178903

申请日：2021-02-18

Applicant: Boston Scientific Scimed, Inc.

Inventor： Amanda L. Smith ,  John T. Favreau ,  Travis Henchie ,  Joseph W. King ,  Lauren Lydecker ,  Andrew Pic

IPC: A61B17/11 ,  A61F5/00 ,  A61F2/04

Abstract: This disclosure relates generally to the field of devices and procedures for forming an opening between adjacent tissue structures. For example, in an embodiment, a system for forming an opening between body lumens may include a delivery catheter. A first access element may be configured to be positioned against a first body lumen disposed about a distal end of the catheter. A second access element having an outer diameter that substantially matches an outer diameter of the first access element may be disposed about the distal end of the catheter. The second access element may be configured to be positioned against a second body lumen and axially aligned with the first access element. A filament may be electrically coupled to one or both of the first and second access element.

公开(公告)号：US10786596B2

公开(公告)日：2020-09-29

申请号：US16245780

申请日：2019-01-11

Applicant: Boston Scientific Scimed, Inc.

Inventor： Gerald Fredrickson ,  Amanda L. Smith ,  Andrew Pic ,  Sophia Gervasio ,  Lauren Lydecker

IPC: A61K31/722 ,  A61L26/00 ,  A61L31/16 ,  A61L31/04 ,  A61M25/09

Abstract: In various aspects, the present disclosure pertains to methods of treating or preventing bleeding at a tissue site comprising applying a chitosan powder composition to the tissue site. In various aspects, the present disclosure pertains to chitosan powder compositions for application to a tissue site, where the powder compositions comprise a chitosan salt, a crosslinked chitosan, a derivatized chitosan, or a combination thereof. In various aspects, the disclosure pertains to catheter assemblies, which are preloaded with a chitosan powder composition and which are configured to deliver the chitosan powder composition a tissue site.