公开(公告)号：US20190290913A1

公开(公告)日：2019-09-26

申请号：US16347940

申请日：2017-11-08

Applicant: GALVANI BIOELECTRONICS LIMITED ,  UNIVERSITÉ DE NICE SOPHIA-ANTIPOLIS ,  CENTRE NATIONALE DE LA RECHERCHE SCIENTIFIQUE

Inventor： Philippe BLANCOU ,  Nicolas GLAICHENHAUS ,  Arun SRIDHAR

IPC: A61N1/36

Abstract: Stimulation of neural signalling of an apical splenic nerve can modulate pro- and anti-inflammatory molecules levels, thereby reducing inflammation and providing ways of treating inflammatory disorders.

公开(公告)号：US20190201692A1

公开(公告)日：2019-07-04

申请号：US16302941

申请日：2017-05-19

Applicant: Galvani Bioelectronics Limited ,  The Johns Hopkins University

Inventor： Arun SRIDHAR ,  Liansheng LIU ,  Pankaj Jay PASRICHA

IPC: A61N1/36

CPC classification number: A61N1/36034 ,  A61N1/36017 ,  A61N1/3606 ,  A61N1/36085 ,  A61N1/36171

Abstract: A method for treating conditions associated with impaired glucose control, involving inhibition of signalling by the greater splanchnic nerve leads to a significant improvement in oral glucose tolerance.

公开(公告)号：US20210069504A1

公开(公告)日：2021-03-11

申请号：US16771441

申请日：2018-12-11

Applicant: Galvani Bioelectronics Limited

Inventor： Gerald Edwin HUNSBERGER ,  Arun SRIDHAR

IPC: A61N1/36 ,  A61N1/05

Abstract: Modulation of neural activity of a ganglion, by applying a signal to a sympathetic nerve adjacent to the ganglion, results in preferential reduction of sympathetic signals to an effector, thereby providing ways of treating and preventing conditions associated with exacerbated sympatho-excitation.

公开(公告)号：US20190184172A1

公开(公告)日：2019-06-20

申请号：US16328090

申请日：2017-08-25

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ,  GALVANI BIOELECTRONICS LIMITED

Inventor： Jeffrey Laurence ARDELL ,  Kalyanam SHIVKUMAR ,  Arun SRIDHAR

IPC: A61N1/36 ,  A61N1/05 ,  A61N1/362

CPC classification number: A61N1/36114 ,  A61N1/0556 ,  A61N1/36057 ,  A61N1/362

Abstract: Modulation, preferably inhibition, of neurosignaling of a cardiac-related sympathetic nerve in the extracardiac intrathoracic neural circuit is effective in stabilizing cardiac electrical and/or mechanical function, thereby providing ways of treating or preventing cardiac dysfunction such as arrhythmias.

公开(公告)号：US20180214691A1

公开(公告)日：2018-08-02

申请号：US15749063

申请日：2016-08-03

Applicant: GALVANI BIOELECTRONICS LIMITED ,  DUKE UNIVERSITY

Inventor： Hans Jakob Kristoffer FAMM ,  Warren Murray GRILL ,  James Arthur HOKANSON ,  Christopher Lawrence LANGDALE ,  Arun SRIDHAR

IPC: A61N1/36 ,  A61N1/372 ,  A61P13/10

Abstract: The present invention provides improved devices, systems and methods to provide for control of bladder function. Aspects of the present disclosure relate to an apparatus, system and/or a method for modulating the neural activity of afferent fibres of the pelvic nerve to bladder function. In one aspect, the disclosure relates to the use of pharmaceutical compositions in patients undergoing neuromodulation therapy.