公开(公告)号：US09937075B2

公开(公告)日：2018-04-10

申请号：US15714441

申请日：2017-09-25

Applicant: Clearside Biomedical, Inc.

Inventor： Rafael Victor Andino ,  Vladimir Zarnitsyn ,  Jesse Yoo ,  Christopher John Brooks ,  Trent John Kahute ,  Justin William Arsenault ,  David Jackson Trettin ,  Andrew Kent Bauer ,  Stephanie Elaine Lewis

IPC: A61M5/00 ,  A61F9/00 ,  A61J1/20 ,  A61M5/20 ,  A61M5/32 ,  A61M5/34 ,  A61M5/46 ,  A61M5/48 ,  A61M37/00

CPC classification number: A61F9/0017 ,  A61F2250/0007 ,  A61F2250/0069 ,  A61J1/201 ,  A61J1/2055 ,  A61J1/2096 ,  A61M5/2033 ,  A61M5/2053 ,  A61M5/31 ,  A61M5/3293 ,  A61M5/34 ,  A61M5/344 ,  A61M5/346 ,  A61M5/347 ,  A61M5/348 ,  A61M5/349 ,  A61M5/46 ,  A61M5/482 ,  A61M37/0015 ,  A61M2005/31508 ,  A61M2037/0023 ,  A61M2037/0061 ,  A61M2210/0612

Abstract: An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.