公开(公告)号：US08529426B2

公开(公告)日：2013-09-10

申请号：US12012220

申请日：2008-01-30

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Nathan P. Myhrvold ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Nathan P. Myhrvold ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： A61N5/00

CPC分类号： A61K41/0057

摘要： A method, composition and system respond to ionizing radiation to adjust biological activity. In some approaches the ionizing radiation is X-ray or extreme ultraviolet radiation that produces luminescent responses that induce biologically active responses.

公开(公告)号：US08164074B2

公开(公告)日：2012-04-24

申请号：US11975702

申请日：2007-10-18

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Nathan P. Myhrvold ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Nathan P. Myhrvold ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N21/64

CPC分类号： A61K41/0057 ,  A61K41/0019 ,  A61K41/0042

摘要： A method, composition and system respond to ionizing radiation to adjust biological activity. In some approaches the ionizing radiation is X-ray or extreme ultraviolet radiation that produces luminescent responses that induce biologically active responses.

公开(公告)号：US08041005B2

公开(公告)日：2011-10-18

申请号：US11906161

申请日：2007-09-28

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N23/223

CPC分类号： G01N23/223 ,  G01N2223/076

摘要： One aspect relates to inducing at least one induced X-ray fluorescing photon within an at least some matter of an at least a portion of an at least one individual responsive to a substantial single input energy event based at least partially on an at least some input energy being applied to the at least some matter of the at least the portion of the at least one individual; and detecting the at least one induced X-ray fluorescing photon; and X-ray fluorescence visualizing, imaging, or information providing within the at least some matter of the at least the portion of the at least one individual responsive to the detecting the at least one induced X-ray fluorescing photon.

摘要翻译： 一个方面涉及至少部分地基于至少一些输入而在至少一个个体的至少一部分的至少一些物质内诱导至少一个诱导的X射线荧光光子，所述至少一个个体响应于基本的单个输入能量事件 能量被施加到至少一个个体的至少一部分的至少一些物质; 以及检测所述至少一个诱导的X射线荧光光子; 以及响应于检测所述至少一个诱导的X射线荧光光子，在所述至少一个个体的至少一部分的至少一些物质内提供X射线荧光可视化，成像或信息。

公开(公告)号：US07975894B2

公开(公告)日：2011-07-12

申请号：US11897974

申请日：2007-08-31

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： A61B17/068

CPC分类号： A61B17/072 ,  A61B17/00491 ,  A61B17/068 ,  A61B2017/00022 ,  A61B2017/00221 ,  A61B2017/00398 ,  A61B2017/00402 ,  A61B2017/00871 ,  A61B2017/07214 ,  A61B2017/07278 ,  A61B2017/2905

摘要： Embodiments include a surgical device and a method. An embodiment of the surgical instrument includes at least one grasping jaw, the at least one grasping jaw being adapted to deliver surgical fasteners by a force generated from a force generator mechanism that is contained within the at least one grasping jaw or is in a proximity to the at least one grasping jaw. Another embodiment includes at least one grasping jaw, at least one actuation mechanism adapted to deliver surgical fasteners, the actuation mechanism being located in a proximity to or contained within the at least one grasping jaw, the surgical fasteners containing at least one shape-transforming material, at least one sensor, at least one chemical tissue sealant and at least one cutter. A method includes: grasping a body tissue with at least one grasping jaw, adjusting a configuration of the grasping in response to a signal or a datum or an image, and releasing a surgical staple or fastener in response to the signal, datum or image.

摘要翻译： 实施例包括手术装置和方法。 手术器械的一个实施例包括至少一个抓持爪，所述至少一个抓持爪适于通过由力产生机构产生的力来输送手术紧固件，所述力产生机构包含在所述至少一个抓握爪内，或者靠近 所述至少一个抓握爪。 另一个实施例包括至少一个抓持爪，至少一个致动机构，其适于递送手术紧固件，所述致动机构位于所述至少一个抓持爪附近或者包含在所述至少一个抓持爪内，所述手术紧固件包含至少一个形状转换材料 ，至少一个传感器，至少一个化学组织密封剂和至少一个切割器。 一种方法包括：用至少一个抓握爪抓住身体组织，响应于信号或基准或图像调整抓握的构型，以及响应于信号，基准或图像释放外科钉或紧固件。

公开(公告)号：US07832611B2

公开(公告)日：2010-11-16

申请号：US11804219

申请日：2007-05-16

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： A61B17/068

CPC分类号： A61B17/072 ,  A61B17/00491 ,  A61B17/068 ,  A61B2017/00022 ,  A61B2017/00221 ,  A61B2017/00398 ,  A61B2017/00402 ,  A61B2017/00871 ,  A61B2017/07214 ,  A61B2017/07278 ,  A61B2017/2905

摘要： Embodiments include a surgical device and a method. An embodiment of the surgical instrument includes at least one grasping jaw, the at least one grasping jaw being adapted to deliver surgical staples by a force generated from a force generator mechanism that is contained within the at least one grasping jaw or is in a proximity to the at least one grasping jaw. Another embodiment includes at least one grasping jaw, at least one delivery mechanism adapted to deliver surgical fasteners, the delivery mechanism being located in a proximity to or contained within the at least one grasping jaw, the surgical fasteners containing at least one shape-transforming material, at least one sensor, at least one chemical tissue sealant and at least one cutter. A method includes: grasping a body organ/tissue with at least one grasping jaw, adjusting a configuration of the grasping in response to a signal or a datum or an image, and releasing a surgical staple/fastener in response to the signal, datum or image.

公开(公告)号：US07798385B2

公开(公告)日：2010-09-21

申请号：US11901955

申请日：2007-09-18

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： A61B17/068

CPC分类号： A61B17/068 ,  A61B17/00491 ,  A61B17/072 ,  A61B2017/00022 ,  A61B2017/00221 ,  A61B2017/00398 ,  A61B2017/00402 ,  A61B2017/00871 ,  A61B2017/07214 ,  A61B2017/07278 ,  A61B2017/2905

摘要： Embodiments include a surgical device and a method. An embodiment of the surgical instrument includes at least one grasping jaw, the at least one grasping jaw being adapted to deliver surgical staples by a force generated from a force generator mechanism that is contained within the at least one grasping jaw or is in a proximity to the at least one grasping jaw. Another embodiment includes at least one grasping jaw, at least one actuation mechanism adapted to deliver surgical staples, the actuation mechanism being located in a proximity to or contained within the at least one grasping jaw, the surgical staples containing at least one shape-transforming material, at least one sensor, at least one chemical tissue sealant and at least one cutter. A method includes: grasping a body tissue with at least one grasping jaw, adjusting a configuration of the grasping in response to a signal or a datum or an image, and releasing a surgical staple/fastener in response to the signal, datum or image.

公开(公告)号：US07777357B2

公开(公告)日：2010-08-17

申请号：US11973343

申请日：2007-10-05

申请人： Roderick A. Hyde ,  William H. Gates, III ,  Muriel Y. Ishikawa ,  Jordin T. Kare ,  Nathan P. Myhrvold ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Roderick A. Hyde ,  William H. Gates, III ,  Muriel Y. Ishikawa ,  Jordin T. Kare ,  Nathan P. Myhrvold ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： F02B71/00

CPC分类号： H02K7/1884 ,  B60L7/14 ,  B60L11/005 ,  B60L11/14 ,  B60L15/2009 ,  B60L2210/40 ,  B60L2220/12 ,  B60L2220/14 ,  B60L2240/12 ,  B60L2240/14 ,  B60L2240/36 ,  B60L2240/421 ,  B60L2240/429 ,  B60L2240/441 ,  B60L2240/642 ,  B60L2240/662 ,  B60L2270/12 ,  F02B63/04 ,  F02B63/041 ,  Y02T10/641 ,  Y02T10/645 ,  Y02T10/70 ,  Y02T10/7022 ,  Y02T10/7077 ,  Y02T10/7241 ,  Y02T10/7275 ,  Y02T10/7291 ,  Y02T90/16

摘要： An engine includes a cylinder having two ends, a piston slidably disposed in the cylinder and a converter operable with the piston to convert mechanical energy of the piston from and to electrical energy.

摘要翻译： 发动机包括具有两端的气缸，可滑动地设置在气缸中的活塞和可与活塞一起工作的转换器，以将活塞的机械能从电能转换成电能。

公开(公告)号：US07724867B2

公开(公告)日：2010-05-25

申请号：US11906135

申请日：2007-09-28

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N23/223

CPC分类号： A61B6/503 ,  A61B5/415 ,  A61B5/418 ,  A61B5/489 ,  A61B6/12 ,  A61B6/14 ,  A61B6/4021 ,  A61B6/4291 ,  A61B6/482 ,  A61B6/485 ,  A61B6/50 ,  A61B6/501 ,  A61B6/502 ,  A61B6/504 ,  A61B6/505 ,  A61B6/506 ,  A61B6/507 ,  A61B6/508 ,  A61B2503/40 ,  G01N23/223 ,  G01N2223/076

摘要： One aspect relates to detecting at least one induced X-ray fluorescing photon fluoresced from substantially within an at least some matter of an at least a portion of an at least one individual at least partially as a result of receiving at least one induced X-ray fluorescing photon generated at least partially within at least one X-ray fluorescence event within the at least some matter of the at least the portion of the at least one individual which has been generated responsive to an at least some input energy resulting from a single input energy event, wherein the at least one induced X-ray fluorescing photon that has passed through the at least some matter of the at least the portion of the at least one individual is at a level to substantially limit interference between the at least one induced X-ray fluorescing photon with an at least one other induced X-ray fluorescing photon that travel for distances greater than a prescribed limit through the at least some matter of the at least the portion of the at least one individual, wherein the at least one other induced X-ray fluorescing photon attenuates by a prescribed percentage after passing through the prescribed distance through the at least some matter of the at least the portion of the at least one individual.

摘要翻译： 一个方面涉及至少部分地检测至少一个感兴趣的X射线荧光光子，其基本上在至少一个个体的至少一部分的至少一些物质内发射，作为接收至少一个诱导X射线 至少部分地在至少一个X射线荧光事件中产生荧光光子，所述至少一个X射线荧光事件在所述至少一个个体的至少一部分中的至少一些物质中响应于由单个输入产生的至少一些输入能量而产生 能量事件，其中已经通过所述至少一个个体的至少一部分的至少一些物质的所述至少一个感兴趣的X射线荧光光子处于基本上限制所述至少一个诱导X 具有至少一个其它诱导的X射线荧光光子的荧光光子，其行进距离大于规定的极限，通过至少一些事件 所述至少一个个体的部分，其中所述至少一个其它诱导的X射线荧光光子在经过所述规定距离之后通过所述至少一个的所述至少一部分的所述至少一些物质衰减预定百分比 个人。

公开(公告)号：US07711089B2

公开(公告)日：2010-05-04

申请号：US11786776

申请日：2007-04-11

申请人： Edward S. Boyden ,  Glenn B. Foster ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Glenn B. Foster ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N23/201

CPC分类号： G01N23/201

摘要： A visualization or imaging system involves inducing and/or detecting Compton scattered X-rays to provide information or a visual representation of a portion of an individual. In one approach, the Compton scattered X-rays are converted to a visible or detectible representations through scintillation.

摘要翻译： 可视化或成像系统包括诱导和/或检测康普顿散射的X射线以提供个体的一部分的信息或视觉表示。 在一种方法中，康普顿散射的X射线通过闪烁转换为可见或可检测的表示。

公开(公告)号：US07664224B2

公开(公告)日：2010-02-16

申请号：US12002287

申请日：2007-12-14

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N23/223

CPC分类号： G01N23/223 ,  G01N2223/076

摘要： One aspect can relate to detecting a presence of an at least one chemical, compound, or biological material contained in an at least some matter of an at least a portion of an at least one individual based at least partially on addition of an at least one chemical identifying additive to the at least some matter of the at least the portion of the at least one individual based at least partially on a generation of an at least one induced X-ray fluorescing photon within the at least one chemical identifying additive responsive to a single input energy event in which an at least some input energy is being applied proximal to the at least one chemical, compound, or biological material contained in the at least some matter of the at least the portion of the at least one individual.

摘要翻译： 一个方面可以涉及至少部分地基于添加至少一个个体的至少一个个体的至少一部分的至少一些物质中的至少一种化学，化合物或生物材料的存在来检测 至少部分地至少部分地基于在所述至少一种化学鉴定添加剂中产生至少一种诱导的X射线荧光光子的化学鉴定添加剂至少部分至少一部分物质的化学鉴定添加剂，其响应于 单输入能量事件，其中至少一些输入能量被施加在至少一个化学，化合物或生物材料的近端，该至少一种化学，化合物或生物材料包含在至少一个个体的至少一部分的该至少一些物质中。