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公开(公告)号：US08460359B2
公开(公告)日：2013-06-11
申请号：US12686138
申请日：2010-01-12
申请人： Charles W. Agnew
发明人： Charles W. Agnew
CPC分类号： A61F2/966 , A61B2017/1205 , A61B2017/12054 , A61F2/013 , A61F2/2412 , A61F2/2475 , A61F2/90 , A61F2/95 , A61F2002/015 , A61F2002/018 , A61F2002/9665 , A61F2220/0016 , A61F2230/0006 , A61F2230/0069
摘要： Medical device delivery systems that include a distal protection feature are provided. A distal tip member that includes a distal protection device and a mounting region for a self-expandable, intraluminal medical device is slidably disposed within a passageway defined by a tubular member.
摘要翻译： 提供了包括远端保护功能的医疗设备传送系统。 包括远侧保护装置和用于自扩张的管腔内医疗装置的安装区域的远侧末端构件可滑动地设置在由管状构件限定的通道内。
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公开(公告)号：US20130079868A1
公开(公告)日：2013-03-28
申请号：US13686038
申请日：2012-11-27
申请人： Charles W. Agnew
发明人： Charles W. Agnew
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2475 , A61F2220/0008 , A61F2220/0016 , A61F2220/005 , A61F2220/0066 , A61F2230/0026 , A61F2230/0095 , A61F2240/001
摘要： Methods of reducing retrograde fluid flow through a valve within a body vessel are provided. The methods can include the steps of identifying a valve exhibiting an undesirable amount of retrograde fluid flow within a body vessel, such as a venous valve or a heart valve, and providing a means for reducing the retrograde fluid flow. A medical device providing a desired amount of retrograde fluid flow can be modified after permitting the medical device to remain in a body cavity for a remodeling-effective time period. The implanted medical device can be modified by subsequently reducing the amount of retrograde fluid flow permitted across the implanted prosthetic valve within the body vessel.
摘要翻译： 提供了通过体内血管中的瓣膜减少逆行液体流动的方法。 所述方法可以包括以下步骤：识别在体内容器（例如静脉瓣膜或心脏瓣膜）中呈现不期望量的逆行流体流动的瓣膜，并提供减少逆行流体流动的装置。 提供所需量的逆行流体流动的医疗装置可以在允许医疗装置保持在体腔中用于重塑有效时间段之后被修改。 可以通过随后减少允许穿过体内容器内植入的假体瓣膜的逆行流体流量来修改植入的医疗装置。
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公开(公告)号：US08109990B2
公开(公告)日：2012-02-07
申请号：US12711915
申请日：2010-02-24
IPC分类号： A61F2/82
CPC分类号： A61F2/2418 , A61F2/01 , A61F2/2412 , A61F2/2475 , A61F2/848 , A61F2/86 , A61F2/88 , A61F2002/016 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2220/0066 , A61F2220/0075 , A61F2230/0013 , A61F2230/0021 , A61F2230/0026
摘要： A low profile support frame for use as an or in an expandable intraluminal medical device includes first and second wire members that define arcuate paths having opposing curves. Connectors join the wire members, and barbs can be disposed on the connectors. The support frame has radially compressed and radially expanded configurations. When the support frame is in the radially expanded configuration, substantially no portion of the support frame is disposed on a first transverse axis of the frame opposite one end of the frame and substantially no portion of the frame is disposed on a second transverse axis of the frame opposite the other end of the frame. The support frame can be used as an intraluminal medical device by itself or as a component in a medical device that includes other components, such as a stent, prosthetic valve, occluder, or filter.
摘要翻译： 用作可扩展管腔内医疗装置中的或在可扩展的管腔内医疗装置中的低调支撑框架包括限定具有相对曲线的弓形路径的第一和第二线构件。 连接器连接线构件，倒钩可以设置在连接器上。 支撑框架具有径向压缩和径向扩张的构造。 当支撑框架处于径向展开构型时，支撑框架的基本上没有部分设置在与框架的一端相对的框架的第一横向轴线上，并且基本上没有框架的任何部分设置在框架的第二横向轴线上 框架与框架的另一端相对。 支撑框架可以作为管腔内医疗装置本身或作为包括其它部件（例如支架，假体瓣膜，封堵器或过滤器）的医疗装置中的部件使用。
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公开(公告)号：US20110288621A1
公开(公告)日：2011-11-24
申请号：US13118724
申请日：2011-05-31
申请人： Charles W. Agnew
发明人： Charles W. Agnew
IPC分类号： A61F2/82
CPC分类号： A61F2/2418 , A61F2/2475 , A61F2210/0004 , A61F2230/0013 , A61F2250/0067
摘要： Prosthetic valves, methods of making medical devices, and methods of treatment are provided. The prosthetic valves of the invention have a valve portion moveable between first and second positions, and a spacing member that has a thickness and protects a portion of the valve portion from contact with a wall of a vessel in which the prosthetic valve is implanted, and/or another structural component of the prosthetic valve, such as a support frame.
摘要翻译： 提供假体瓣膜，制造医疗装置的方法和治疗方法。 本发明的人工瓣膜具有可在第一和第二位置之间移动的阀部分，以及间隔部件，其具有厚度并保护阀部分的一部分不与其中植入人工瓣膜的血管的壁接触，以及 /或人造瓣膜的另一结构部件，例如支撑框架。
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公开(公告)号：US07648527B2
公开(公告)日：2010-01-19
申请号：US11708860
申请日：2007-02-21
申请人： Charles W. Agnew
发明人： Charles W. Agnew
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2475 , A61F2220/0008 , A61F2220/0016 , A61F2220/005 , A61F2220/0066 , A61F2230/0026 , A61F2230/0095 , A61F2240/001
摘要： Methods of reducing retrograde fluid flow through a valve within a body vessel are provided. The methods can include the steps of identifying a valve exhibiting an undesirable amount of retrograde fluid flow within a body vessel, such as a venous valve or a heart valve, and providing a means for reducing the retrograde fluid flow. A medical device providing a desired amount of retrograde fluid flow can be modified after permitting the medical device to remain in a body cavity for a remodeling-effective time period. The implanted medical device can be modified by subsequently reducing the amount of retrograde fluid flow permitted across the implanted prosthetic valve within the body vessel.
摘要翻译： 提供了通过体内血管中的瓣膜减少逆行液体流动的方法。 所述方法可以包括以下步骤：识别在体内容器（例如静脉瓣膜或心脏瓣膜）中呈现不期望量的逆行流体流动的瓣膜，并提供减少逆行流体流动的装置。 提供所需量的逆行流体流动的医疗装置可以在允许医疗装置保持在体腔中用于重塑有效时间段之后被修改。 可以通过随后减少允许穿过体内容器内植入的假体瓣膜的逆行流体流量来修改植入的医疗装置。
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16.发明授权公开(公告)号：US07563276B2
公开(公告)日：2009-07-21
申请号：US11260981
申请日：2005-10-28
IPC分类号： A61F2/06
CPC分类号： A61F2/2418 , A61F2/2475 , A61F2220/0016 , A61F2220/0058 , A61F2220/0075 , A61F2230/0026 , A61F2230/0067 , A61F2230/0095
摘要： Prosthetic valves for regulating fluid flow through a body vessel are described. The valves include a valve member that includes at least a portion that is capable of moving to selectively permit and substantially prevent fluid flow through the body vessel, either alone or with one or more additional valve members. A cannula is associated with the valve and permits a controlled amount of fluid flow through the valve, such as retrograde flow while the valve member substantially prevents fluid flow through the body vessel.
摘要翻译： 描述了用于调节通过身体血管的流体流动的假体瓣膜。 阀包括阀构件，该阀构件包括至少一部分，其能够移动以选择性地允许和基本上防止流体流过身体容器，单独地或与一个或多个附加的阀构件。 套管与阀相关联并且允许受控量的流体流过阀，例如逆流，同时阀构件基本上防止流体流过身体血管。
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公开(公告)号：US07527643B2
公开(公告)日：2009-05-05
申请号：US11139930
申请日：2005-05-27
申请人： Brain C. Case , Charles W. Agnew , Ram H. Paul
发明人： Brain C. Case , Charles W. Agnew , Ram H. Paul
IPC分类号： A61F2/06
摘要： Exchangeable delivery systems, methods of making delivery systems, and methods of delivering a self-expandable prosthetic device are provided. Delivery systems according to embodiments of the invention include an elongate tubular member defining a passageway with a distal end defining an exchange port, and a distal tip member slideably disposed partially within the distal end of the passageway.
摘要翻译： 提供可交换的输送系统，制备输送系统的方法以及递送自膨胀假体装置的方法。 根据本发明的实施例的递送系统包括限定具有限定交换口的远端的通道的细长管状构件，以及部分地可滑动地设置在通道的远端内的远侧末端构件。
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公开(公告)号：US20080183280A1
公开(公告)日：2008-07-31
申请号：US12021624
申请日：2008-01-29
申请人： Charles W. Agnew , James B. Hunt
发明人： Charles W. Agnew , James B. Hunt
IPC分类号： A61F2/06
CPC分类号： A61F2/2418 , A61F2/2475 , A61F2002/8483 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/0076
摘要： The invention relates to a prosthetic valve for regulating flow through a body lumen. The medical device comprises discrete shaping members, a flexible covering, and a valve member. The discrete shaping members are operatively attached to the flexible covering, such that the medical device may exhibit low radial force and dynamic movement.
摘要翻译： 本发明涉及一种用于调节通过体腔流动的人造瓣膜。 医疗装置包括离散的成形构件，柔性覆盖物和阀构件。 分立的成形构件可操作地附接到柔性覆盖物，使得医疗装置可以表现出低的径向力和动态运动。
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公开(公告)号：US20080064988A1
公开(公告)日：2008-03-13
申请号：US11846743
申请日：2007-08-29
IPC分类号： A61M25/00
CPC分类号： A61M25/09 , A61M25/0045 , A61M25/0069 , A61M2025/09075 , A61M2025/09175
摘要： A wire guide and a medical system including an elongate member having a releasably connected loop are provided. The wire guide includes an elongate shaft having a proximal portion and a distal portion. The distal portion of the shaft includes a loop releasably connected to the shaft in a first looped configuration. The loop is disconnectable at a detachment point and forms a second configuration wherein the loop is at least partially disconnected from the shaft. A method of making the wire guide and a method of disconnecting a loop portion of a medical device are also provided.
摘要翻译： 提供了一种线引导件和医疗系统，其包括具有可释放地连接的环的细长构件。 线引导件包括具有近端部分和远端部分的细长轴。 轴的远端部分包括以第一环形构造可释放地连接到轴的环。 环路在分离点处是可断开的，并且形成第二配置，其中环路至少部分地与轴断开连接。 还提供了一种制造导线器的方法和一种断开医疗装置的环路部分的方法。
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公开(公告)号：US08734426B2
公开(公告)日：2014-05-27
申请号：US12905254
申请日：2010-10-15
申请人： Mahfuza Ahmed , Tyler J. Bunch , Charles W. Agnew , Kate Duncan , James B. Hunt , Bonita L. Nickless , Nancy L. Hutchinson
发明人： Mahfuza Ahmed , Tyler J. Bunch , Charles W. Agnew , Kate Duncan , James B. Hunt , Bonita L. Nickless , Nancy L. Hutchinson
IPC分类号： A61M27/00
CPC分类号： A61M25/04 , A61M2025/0163 , A61M2027/004
摘要： A drainage catheter includes an elongated tubular member, a locking assembly engaged with a proximal end of the tubular member, and a tension member for drawing a distal end of the tubular member into a desired configuration. The locking assembly includes a connector, a locking arm, and a locking mechanism. The connector has an exterior surface profile that corresponds with an interior surface profile of the locking arm. The locking arm is pivotably attached to the connector to enable pivoting movement of the locking arm between an unlocked position and a locked position whereby the tension member is secured between the locking arm and the connector when the arm is in the locked position. The locking assembly may alternatively comprise a connector and a sliding sleeve or a connector having a clamping element disposed therein.
摘要翻译： 排水导管包括细长管状构件，与管状构件的近端接合的锁定组件和用于将管状构件的远端拉伸成所需构造的张紧构件。 锁定组件包括连接器，锁定臂和锁定机构。 连接器具有与锁定臂的内表面轮廓对应的外表面轮廓。 锁定臂可枢转地附接到连接器，以使得锁定臂能够在解锁位置和锁定位置之间枢转运动，由此当臂处于锁定位置时，张力构件固定在锁定臂和连接器之间。 锁定组件可以可选地包括连接器和滑动套筒或具有设置在其中的夹紧元件的连接器。
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