公开(公告)号：US20070069731A1

公开(公告)日：2007-03-29

申请号：US10557829

申请日：2004-05-21

Applicant: Cheng Ni ,  Ting Xue

Inventor： Cheng Ni ,  Ting Xue

IPC: G01V3/00

CPC classification number: G01R33/3873 ,  G01R33/3806

Abstract: In a magnetic resonance imaging apparatus and a method for shimming such an apparatus, at each of mirror-symmetrical assemblies respectively disposed at opposite faces of a static magnetic field generator, that each include a shimming ring, an additional shimming ring is provided that is adjustable in position relative to the other shimming ring to shim the static magnetic field. Additionally or alternatively, at each face of the static magnetic field generator, a permanently magnetic arrangement is provided that is divided into a number of permanently magnetic columns respectively having different energy levels. Additionally or alternatively, magnetic bolts, such as magnetically conducting bolts or permanently magnetic bolts can be symmetrically inserted into either of the mirror-symmetric assemblies, or the permanently magnetic columns, for additionally shimming adjustment.

Abstract translation: 在磁共振成像装置和用于匀场这种装置的方法中，在分别设置在静磁场发生器的相对面处的每个镜对称组件中，每个包括匀场环，提供了可调节的附加匀场环 在相对于另一个垫圈的位置，以静止磁场。 附加地或替代地，在静态磁场发生器的每个面处，提供永久磁性布置，其被分成多个分别具有不同能级的永久磁性列。 附加地或替代地，诸如导磁螺栓或永久磁性螺栓的磁性螺栓可以对称地插入到任何一个镜对称组件或永久磁柱中，用于额外的调整调整。

公开(公告)号：US20060244451A1

公开(公告)日：2006-11-02

申请号：US11394629

申请日：2006-03-31

Applicant: Cheng Ni ,  Hui Cao ,  Jin Chen ,  Zhong Ren

Inventor： Cheng Ni ,  Hui Cao ,  Jin Chen ,  Zhong Ren

IPC: G01V3/00

CPC classification number: G01R33/3873 ,  G01R33/3875

Abstract: In a shimming method for an irregular object to be examined by magnetic resonant equipment magnetic field parameters are measured at measurement points located on the surface of an irregular object to be examined. Based on the measured magnetic field parameters, the positions and number of shims for adjusting magnetic field homogeneity are calculated when a passive shimming is to be performed, or the current value in a shimming coil are calculated when an active shimming is to be performed, or at the same time both the positions and number of shims and current value in the shimming coil are calculated when active shimming and passive shimming are to be performed at the same time. Shimming is then performed according to the calculated results. These above steps are repeated until achieving required magnetic field homogeneity. Since the homogeneous region is designed to have an irregular shape, it can provide a better coverage of the irregular object to be examined, and at the same time it reduces the shimming constraints to the unnecessary regions outside the irregular object to be examined, therefore avoiding shimming in those unnecessary regions.

Abstract translation: 在通过磁共振设备检查的不规则物体的匀场方法中，在位于待检查的不规则物体的表面上的测量点处测量磁场参数。 基于测量的磁场参数，当要执行被动匀场调整时计算用于调整磁场均匀性的垫片的位置和数量，或者当要执行活动匀场时计算匀场线圈中的当前值，或 同时，当同时进行有效匀场和被动匀场时，同时计算匀场线圈的位置和数量以及匀场线圈中的当前值。 然后根据计算结果执行匀场。 重复上述步骤，直到达到所需的磁场均匀性。 由于均匀区域被设计成具有不规则形状，所以可以提供对待检查的不规则物体的更好的覆盖，并且同时将匀场限制减小到待检查的不规则物体之外的不需要的区域，因此避免 在这些不必要的地区。

公开(公告)号：US06218839B1

公开(公告)日：2001-04-17

申请号：US09317425

申请日：1999-05-24

Applicant: Abdulbasad Shaikh ,  Jeremy Francis Williams ,  Cheng Ni

Inventor： Abdulbasad Shaikh ,  Jeremy Francis Williams ,  Cheng Ni

IPC: G01V300

CPC classification number: G01R33/3875

Abstract: A magnetic resonance imaging system comprises a magnet (30) for generating a main magnetic field, a gradient coil (34) to superimpose a linearly varying magnetic field over the main magnetic field, and an RF coil (34) forming part of a transmit/receive system for signals which are used to construct an image. A shimset (32) is positioned between the magnet (30) and the gradient coil (34) to provide magnetic field correction and is constructed so as not to have axial and azimuthal symmetry. This is achieved by providing cutout portions (38) in the shimset (32) which are diametrically opposite each other, similar cutouts (40) being provided in the gradient coil (34) which are aligned with the cutout portions (38). The cutout portions (38, 40) accommodate the shoulders of larger patients, therefore reducing the need to extend the bore size of the magnetic resonance imaging system.

Abstract translation: 磁共振成像系统包括用于产生主磁场的磁体（30），用于在主磁场上叠加线性变化的磁场的梯度线圈（34），以及形成发射/ 接收用于构建图像的信号的系统。 垫片（32）位于磁体（30）和梯度线圈（34）之间，以提供磁场校正，并被构造为不具有轴向和方位对称性。 这通过在垫片（32）中提供彼此径向相对的切口部分（38）来实现，类似的切口（40）设置在与切口部分（38）对准的梯度线圈（34）中。 切口部分（38,40）容纳较大患者的肩部，因此减少了延长磁共振成像系统的孔尺寸的需要。

公开(公告)号：US08401614B2

公开(公告)日：2013-03-19

申请号：US12708838

申请日：2010-02-19

Applicant: Xiao Dong Zhou ,  Cheng Ni

Inventor： Xiao Dong Zhou ,  Cheng Ni

IPC: A61B5/05

CPC classification number: G01R33/4804 ,  A61B2017/00084 ,  A61B2090/374 ,  A61N7/02 ,  G01K7/36 ,  G01K2213/00 ,  G01R33/4814

Abstract: A method for reducing errors in the measurement of temperature by magnetic resonance, for use in magnetic resonance imaging-guided HIFU equipment, includes acquiring an MR phase image, as a reference image, before heating an area to be heated with the HIFU equipment; acquiring another MR phase image, as a heated image, during or after the heating by the HIFU equipment; and calculating the temperature change in the heated area according to said heated image and said reference image; and making compensation to said temperature change according to the change in the magnetic field caused by the position change of an ultrasonic transducer in said HIFU equipment. The method can reduce significantly the temperature errors resulting from the position changes of the ultrasonic transducer.

Abstract translation: 在磁共振成像引导的HIFU设备中使用的用于减小用于磁共振的温度测量误差的方法包括在用HIFU设备加热待加热的区域之前获取作为参考图像的MR相位图像; 在HIFU设备加热期间或之后获取作为加热图像的另一MR相图像; 以及根据所述加热图像和所述参考图像计算加热区域中的温度变化; 并且根据由所述HIFU设备中的超声波换能器的位置变化引起的磁场变化对所述温度变化进行补偿。 该方法可以显着降低由超声波换能器的位置变化引起的温度误差。

公开(公告)号：US20060267715A1

公开(公告)日：2006-11-30

申请号：US10557818

申请日：2004-05-21

Applicant: Cheng Ni ,  Ting Xue

Inventor： Cheng Ni ,  Ting Xue

IPC: H01F3/00

CPC classification number: G01R33/383

Abstract: A magnetic field generating system suitable for use in a magnetic resonance apparatus has mirror-symmetrical assemblies disposed at opposite faces of a supporting structure, each assembly having a pole plate located between a pulsed magnetic field excitation coil and a static magnetic field generating source. Each pole plate is formed by a number of pole plate segments that either electrically insulated from each other, or conduct between adjacent segments only at single points, without forming a conductive loop. Eddy current propagation is thereby suppressed.

Abstract translation: 适用于磁共振装置的磁场产生系统具有设置在支撑结构的相对面处的镜对称组件，每个组件具有位于脉冲磁场激励线圈和静磁场产生源之间的极板。 每个极板由多个彼此电绝缘的极板段形成，或仅在单个点处在相邻段之间导通，而不形成导电环。 由此抑制涡流传播。

公开(公告)号：US08476904B2

公开(公告)日：2013-07-02

申请号：US13052626

申请日：2011-03-21

Applicant: Marc Beckmann ,  Cheng Ni ,  Xiao Dong Zhou

Inventor： Marc Beckmann ,  Cheng Ni ,  Xiao Dong Zhou

IPC: G01V3/00

CPC classification number: A61B5/015 ,  A61B5/055 ,  G01R33/4804 ,  G01R33/5616

Abstract: A method for magnetic resonance imaging, in which a magnetic resonance imaging device employs a multi-echo imaging sequence, includes the steps of: applying, to one of the multiple echoes, a first number of steps of phase encoding, applying a readout gradient, and collecting the data of this echo to reconstruct an anatomical image; and applying, to another one of the multiple echoes, a second number of steps of phase encoding, applying a readout gradient, and collecting the data of this echo to construct a temperature image. The method is capable of obtaining at the same time both a temperature image with high time resolution and an anatomical image with high spatial resolution.

Abstract translation: 一种磁共振成像方法，其中磁共振成像装置采用多回波成像序列，包括以下步骤：将多个回波中的一个应用于相位编码的第一数量级，应用读出梯度， 并收集该回波的数据以重建解剖图像; 以及将多个回波中的另一个应用到相位编码的第二数量级，应用读出梯度，以及收集该回波的数据以构成温度图像。 该方法能够同时获得具有高时间分辨率的温度图像和具有高空间分辨率的解剖图像。

公开(公告)号：US20080068009A1

公开(公告)日：2008-03-20

申请号：US11900819

申请日：2007-09-13

Applicant: Jing Gao ,  Cheng Ni ,  Hong Tao ,  Hai Yu

Inventor： Jing Gao ,  Cheng Ni ,  Hong Tao ,  Hai Yu

IPC: G01R33/022

CPC classification number: G01R33/10 ,  G01R33/022

Abstract: The invention proposes a method and an apparatus for testing a magnetic field of a coil. The method comprises applying an alternating current to the coil to generate an alternating magnetic field; measuring simultaneously the induced electromotive potential at a plurality of positions in the alternating magnetic field; and collecting and processing signals of the induced electromotive potential so as to obtain said coil's magnetic field distribution. The apparatus comprises probes positioned in said alternating magnetic field to generate the induced electromotive potential; a multi-channel data acquisition card for collecting the signals of the potential; and a processor for processing the collected signals to obtain said coil's magnetic field distribution. The method and the apparatus eliminate the interference by the magnetic field of the earth by testing the coil's alternating magnetic field to improve test accuracy and to improve the testing efficiency by multi-channel acquisition of the test signals.

Abstract translation: 本发明提出了一种用于测试线圈的磁场的方法和装置。 该方法包括向线圈施加交流电以产生交变磁场; 同时测量交变磁场中的多个位置处的感应电动势; 并收集和处理感应电动势的信号，以便获得所述线圈的磁场分布。 该装置包括位于所述交变磁场中的探针以产生感应电动势; 用于收集潜在信号的多通道数据采集卡; 以及用于处理所收集的信号以获得所述线圈的磁场分布的处理器。 该方法和装置通过测试线圈的交变磁场来消除地球磁场的干扰，提高测试精度，并通过多通道采集测试信号提高测试效率。

公开(公告)号：US20070257758A1

公开(公告)日：2007-11-08

申请号：US10591639

申请日：2005-03-07

Applicant: Jin Chen ,  Cheng Ni ,  Ting Xue

Inventor： Jin Chen ,  Cheng Ni ,  Ting Xue

IPC: H01F7/00 ,  G01V3/00

CPC classification number: G01R33/3873

Abstract: The present invention relates to a magnetic field adjusting device; such as may be used in MRI apparatus. The device can overcome the magnetic force to enable shimming plugs to move in a controlled continuous manner, thereby achieving continuous adjusting and accurate positioning. The magnetic field adjusting device comprises; a pair of opposing pole plates (3, 31), respectively mounted on magnetic field generating sources, forming a magnetic field space; a plurality of shimming plugs (42) movably mounted at the periphery of said pole plates (3, 31), each shimming plug (42) mounted in a radially oriented retaining groove (45), so as to be movable in the direction of the retaining groove. Additionally, or alternatively, the circumferences of the magnetic field generating sources (5, 51) are arranged with adjusting bars (71, 81) which can move perpendicular to the pole plates. As an advantage of the present invention, the magnetic field can be shimmed conveniently quickly, and accurately to improve the imaging quality.

Abstract translation: 磁场调整装置技术领域本发明涉及磁场调整装置， 例如可用于MRI装置。 该装置可以克服磁力，以使塞子以受控的连续方式移动，从而实现连续的调节和准确的定位。 磁场调节装置包括： 分别安装在磁场产生源上的一对相对极板（3,31），形成磁场空间; 多个可移动地安装在所述极板（3,31）的周边的垫片塞（42），每个垫片塞（42）安装在径向取向的保持槽（45）中，以便可沿着 保持槽。 另外或者替代地，磁场产生源（5,51）的周向布置有可以垂直于极板移动的调节杆（71,81）。 作为本发明的优点，可以方便地快速，准确地对磁场进行补片，以提高成像质量。

公开(公告)号：US06734212B2

公开(公告)日：2004-05-11

申请号：US09975136

申请日：2001-10-10

Applicant: Dexu Zhu ,  Mitsumi Muramatsu ,  Jianshu Xie ,  Cheng Ni ,  Ming-Wei Wang

Inventor： Dexu Zhu ,  Mitsumi Muramatsu ,  Jianshu Xie ,  Cheng Ni ,  Ming-Wei Wang

IPC: A61K3124

CPC classification number: C07C279/18 ,  C07C279/14 ,  G01N2291/0217 ,  G01N2291/0423

Abstract: The invention relates to compositions and methods for treating or preventing disease or disorders caused by or associated with certain bacterial infection, especially Escherichia coli (E. coli) or Helicobacter pylori (H. pylori) infection. One exemplary compound of the present invention has the following formula I: wherein n is 0 or 1, and R is selected from the group consisting of C1-10 alkyl, C6-10 aryl and and wherein when n is 0, R is not C6-10 aryl.

Abstract translation: 本发明涉及用于治疗或预防由某些细菌感染特别是大肠杆菌（E.coli）或幽门螺杆菌（幽门螺杆菌）感染引起或与其相关的疾病或病症的组合物和方法。 本发明的一个示例性化合物具有下式I：其中n为0或1，并且R选自C 1-10烷基，C 6-10芳基，并且其中当n为0时，R不为C 6 - 10芳基。

公开(公告)号：US08638099B2

公开(公告)日：2014-01-28

申请号：US13118794

申请日：2011-05-31

Applicant: Cheng Ni ,  Xiao Dong Zhou

Inventor： Cheng Ni ,  Xiao Dong Zhou

IPC: G01R33/48 ,  A61N7/00

CPC classification number: A61N7/02 ,  A61B2017/00084 ,  A61B2090/374 ,  G01R33/4804 ,  G01R33/4814

Abstract: A method for reducing magnetic resonance temperature measurement errors, which is used for the high-intensity focused ultrasound device for monitoring magnetic resonance imaging includes obtaining a magnetic resonance phase diagram as a reference image before the high-intensity focused ultrasound device heats the heating area; obtaining another magnetic resonance phase diagram as a heating image during or after the heating process of the high intensity focused ultrasound device; calculating the temperature changes in the heating area according to said heating image and reference image. The method further includes measuring the magnetic field changes caused by the position changes of the ultrasonic transducer of said high-intensity focused ultrasound device, and then compensating for the temperature changes according to said magnetic field changes. The present invention can significantly reduce the temperature errors caused by the position changes of the ultrasonic transducer.

Abstract translation: 用于降低磁共振温度测量误差的方法，用于监测磁共振成像的高强度聚焦超声波装置，包括在高强度聚焦超声装置加热加热区域之前获得作为参考图像的磁共振相位图; 在高强度聚焦超声装置的加热过程中或之后获得另一磁共振相图作为加热图像; 根据所述加热图像和参考图像计算加热区域中的温度变化。 该方法还包括测量由所述高强度聚焦超声装置的超声波换能器的位置变化引起的磁场变化，然后根据所述磁场变化补偿温度变化。 本发明能够显着降低由超声波换能器的位置变化引起的温度误差。