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公开(公告)号：US5324310A
公开(公告)日：1994-06-28
申请号：US907369
申请日：1992-07-01
CPC分类号： A61N1/3706 , A61N1/365 , A61N1/3716
摘要： A pacemaker having two bipolar leads, one atrial, one ventricular, each with TIP and RING electrodes, configured as for conventional bipolar pacing/sensing in both chambers. Switching circuitry in the pacemaker is operable to select from among various possible sensing configurations, including one configuration in which sensing is performed between the ring electrodes of the respective pacing/sensing leads. Pacing is preferably performed in a conventional unipolar configuration in each chamber, from the respective tip electrodes. The "ring-to-ring" EGM signal is applied to filtering and EGM amplifier circuitry, and then provided to a telemetry system for transmission to an external receiver. The ring-to-ring EGM signal possesses the high resolution properties of conventional intracardiac signals, and is relatively unaffected by the after-potentials and tissue polarization effects that arise when the same lead is used for pacing and sensing. Additionally, the ring-to-ring EGM signal is a composite of atrial and ventricular electrical signals, and thus has an appearance similar to that of surface ECGS. In the disclosed embodiment, separate atrial and ventricular EGM amplifiers are provided, with the atrial EGM amplifier receiving a conventional atrial unipolar sensing signal and the ventricular EGM amplifier receiving a conventional ventricular unipolar sensing signal. The outputs from the respective atrial and ventricular EGM amplifiers are algebraically multiplied, and the multiplied signal is applied to a threshold detector. Capture is verified when the multiplied signal experiences a positive voltage spike that exceeds a predetermined threshold in the threshold detector.
摘要翻译： 具有两个双极性引线的心脏起搏器，一个心房，一个心室，每个具有TIP和RING电极，配置为在两个腔室中用于常规双极起搏/感测。 起搏器中的切换电路可操作以从各种可能的感测配置中进行选择，包括在相应的起搏/感测引线的环形电极之间进行感测的一种配置。 优选地，在每个室中，从相应的末端电极以常规单极配置进行起搏。 “环到环”EGM信号被应用于滤波和EGM放大器电路，然后提供给遥测系统以传输到外部接收机。 环到环的EGM信号具有常规心内信号的高分辨率特性，并且相对不受当相同引线用于起搏和感测时产生的后电位和组织极化效应的影响。 另外，环到环EGM信号是心房和心室电信号的复合物，因此具有与表面ECGS相似的外观。 在所公开的实施例中，提供单独的心房和心室EGM放大器，其中心房EGM放大器接收常规心房单极性感测信号，并且心室EGM放大器接收常规心室单极性感测信号。 来自相应的心房和心室EGM放大器的输出被代数乘以，并且相乘的信号被施加到阈值检测器。 当倍增的信号在阈值检测器中经历超过预定阈值的正电压尖峰时，验证捕获。
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公开(公告)号：US07209790B2
公开(公告)日：2007-04-24
申请号：US10722891
申请日：2003-11-26
IPC分类号： A61N1/08
CPC分类号： A61N1/37252 , H04B1/385 , H04B1/401 , Y10S128/903
摘要： The invention is directed to a programmer for communication with different medical devices that utilize different telemetry communication techniques. The programmer receives telemetry signals from a given medical device, and selects an appropriate communication mode, which can be pre-programmed into the programmer as one of a plurality of possible communication modes. The programmer can configure itself for communication with a given medical device based on the telemetry signal it receives. Specifically the programmer is implemented as a software based, power efficient receiver/transmitter based upon an inexpensive, simple motor-controller DSP.
摘要翻译： 本发明涉及一种用于与使用不同遥测通信技术的不同医疗设备进行通信的编程器。 编程器从给定的医疗设备接收遥测信号，并且选择适当的通信模式，其可以作为多种可能的通信模式之一被预先编程到编程器中。 编程人员可以根据其接收的遥测信号，将其自身配置为与给定医疗设备进行通信。 具体地说，程序员被实现为基于基于软件的功率效率接收器/发射机，其基于廉价的简单的电动机控制器DSP。
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13.发明授权Implantable medical device using audible sound communication to provide warnings 有权可植入医疗器械采用声音通讯提供警告
公开(公告)号：US6067473A
公开(公告)日：2000-05-23
申请号：US282594
申请日：1999-03-31
CPC分类号： A61N1/37258
摘要： Methods and apparatus for interrogation of implantable medical device (IMD) information, including programmed parameter values, operating modes and programmed changes thereof and data stored in the IMD, by emission of audible sounds by the IMD are disclosed. The IMD includes an audio transducer that emits audible sounds including voiced statements or musical tones stored in analog memory correlated to a programming or interrogation operating algorithm or to a warning trigger event. The audible sounds can comprise the sole uplink transmission or may augment the contemporaneous uplink RF transmission of stored data, and/or programmed operating modes and parameters and/or device operations and states in an interrogation or during programming. To conserve energy, the audible sounds accompanying interrogation and programming of the IMD are at a low volume that preferably cannot be heard without use of an external audio amplifier or stethoscope. Voiced statements warning of battery energy depletion or imminent delivery of a therapy are emitted at a higher volume that is sufficient to be heard by the patient, so that the patient can take appropriate action. The volume of audible sounds confirming programmed changes made by a patient using a limited function programmer or magnet is also increased so that the patient can hear them.
摘要翻译： 公开了通过IMD发出可听见的声音来询问可植入医疗装置（IMD）信息的方法和装置，其中包括编程参数值，操作模式及其编程改变以及存储在IMD中的数据。 IMD包括音频换能器，其发射可听声音，包括存储在与编程或询问操作算法相关的模拟存储器中的语音或音调，或者到警告触发事件。 可听见的声音可以包括唯一的上行链路传输，或者可以在询问中或在编程期间增加存储数据的同时期上行链路RF传输和/或编程的操作模式和参数和/或设备操作和状态。 为了节省能量，伴随着IMD的询问和编程的可听见的声音处于较低的音量，最好在不使用外部音频放大器或听诊器的情况下听不到声音。 电池能量消耗或治疗即将发送的声明声明以足以由患者听到的较高音量发出，以便患者能够采取适当的动作。 使用有限功能的编程器或磁铁确认病人进行的编程改变的可听见声音的音量也增加，以便患者可以听到它们的声音。
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公开(公告)号：USH1347H
公开(公告)日：1994-08-02
申请号：US973358
申请日：1992-11-09
摘要： A method and apparatus for interpreting and displaying the status and diagnostic data of, and/or programming an implantable medical device is disclosed. The apparatus includes a microprocessor with multiple executable programs; data entry means, such as a keyboard or light pen; a display means such as a screen display and/or a printer; and may include a receiver and transmitter means for remote programming and interrogation of the implantable medical device. The apparatus further includes a stored audio signal to represent the status and diagnostic values of the implantable medical device.
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公开(公告)号：US5271395A
公开(公告)日：1993-12-21
申请号：US870062
申请日：1992-04-17
CPC分类号： A61N1/36585
摘要： A rate-responsive cardiac pacemaker comprising a minute ventilation circuit and an activity circuit. The minute ventilation circuit computes a first target pacing rate as a function of measurements of the patient's pleural blood impedance, and the activity circuit computes a second target pacing rate as a function of measured levels of patient activity. A rate control function establishes a rate-responsive pacing rate based on the first and second target pacing rates. The minute ventilation circuit delta-modulates an analog impedance waveform and maintains short-term and long-term weighted averages of delta-modulator output counts. Variations in the difference between the short-term and long-term weighted average values are determinative of the first target pacing rate. Variations in an activity sensor output signal are determinative of the second target pacing rate. Physician-programmable parameters for the pacemaker include selection of a rate-response setting, upper and lower pacing rate limits, and rate-smoothing attack and decay settings.
摘要翻译： 一种速率响应心脏起搏器，包括微通风回路和活动电路。 分钟通气电路根据患者胸膜血阻抗的测量值来计算第一目标起搏速率，并且活动电路根据测量的患者活动水平计算第二目标起搏速率。 速率控制功能基于第一和第二目标起搏速率建立速率响应起搏速率。 分钟通风电路对模拟阻抗波形进行delta调制，并维持Δ调制器输出计数的短期和长期加权平均值。 短期和长期加权平均值差异的变化是第一个目标起搏率的决定因素。 活动传感器输出信号的变化是第二目标起搏速率的决定因素。 心脏起搏器的医师可编程参数包括选择速率响应设置，上限和下限起搏速率限制以及速率平滑攻击和衰减设置。
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16.发明授权System and apparatus for controlled activation of acute use medical devices 有权用于急性用途医疗装置的受控激活的系统和装置公开(公告)号：US08706253B2
公开(公告)日：2014-04-22
申请号：US13226399
申请日：2011-09-06
IPC分类号： A61N1/08
CPC分类号： A61N1/3787 , A61N1/08 , A61N1/378
摘要： An integrated activation system for an implantable medical device (IMD) sharing a power source, the activation system comprising a switching circuit having first and second inputs and having an output coupled to the acute use device, a gating element coupled to the first input and configured to gate power from the power source to the switching circuit, and a sensing element coupled to the second input of the switching circuit. The sensing element is configured to sense an activation condition, enable an operation interval of the switching circuit, and transmit a signal to the switching circuit during the activation condition. The switching circuit is configured to transmit power to the acute use device upon receipt of a pre-determined number of signals from the sensing element.
摘要翻译： 一种用于共享电源的可植入医疗装置（IMD）的集成激活系统，所述激活系统包括具有第一和第二输入并且具有耦合到所述急性使用装置的输出的切换电路，耦合到所述第一输入并配置的门控元件 从电源到开关电路的栅极电力，以及耦合到开关电路的第二输入的感测元件。 感测元件被配置为感测激活条件，启用开关电路的操作间隔，并且在激活条件期间将信号发送到开关电路。 开关电路被配置为在接收到来自感测元件的预定数量的信号时将功率传送到急用设备。
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17.发明申请公开(公告)号：US20120116481A1
公开(公告)日：2012-05-10
申请号：US13226399
申请日：2011-09-06
IPC分类号： A61N1/36
CPC分类号： A61N1/3787 , A61N1/08 , A61N1/378
摘要： An integrated activation system for an implantable medical device (IMD) sharing a power source, the activation system comprising a switching circuit having first and second inputs and having an output coupled to the acute use device, a gating element coupled to the first input and configured to gate power from the power source to the switching circuit, and a sensing element coupled to the second input of the switching circuit. The sensing element is configured to sense an activation condition, enable an operation interval of the switching circuit, and transmit a signal to the switching circuit during the activation condition. The switching circuit is configured to transmit power to the acute use device upon receipt of a pre-determined number of signals from the sensing element.
摘要翻译： 一种用于共享电源的可植入医疗装置（IMD）的集成激活系统，所述激活系统包括具有第一和第二输入并且具有耦合到所述急性使用装置的输出的切换电路，耦合到所述第一输入并配置的门控元件 从电源到开关电路的栅极电力，以及耦合到开关电路的第二输入的感测元件。 感测元件被配置为感测激活条件，启用开关电路的操作间隔，并且在激活条件期间将信号发送到开关电路。 开关电路被配置为在接收到来自感测元件的预定数量的信号时将功率传送到急用设备。
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18.发明授权System and apparatus for controlled activation of acute use medical devices 有权用于急性用途医疗装置的受控激活的系统和装置公开(公告)号：US08014872B2
公开(公告)日：2011-09-06
申请号：US11343354
申请日：2006-01-31
IPC分类号： A61N1/08
CPC分类号： A61N1/3787 , A61N1/08 , A61N1/378
摘要： An integrated activation system for an implantable medical device (IMD) sharing a power source, the activation system comprising a switching circuit having first and second inputs and having an output coupled to the acute use device, a gating element coupled to the first input and configured to gate power from the power source to the switching circuit, and a sensing element coupled to the second input of the switching circuit. The sensing element is configured to sense an activation condition, enable an operation interval of the switching circuit, and transmit a signal to the switching circuit during the activation condition. The switching circuit is configured to transmit power to the acute use device upon receipt of a pre-determined number of signals from the sensing element.
摘要翻译： 一种用于共享电源的可植入医疗装置（IMD）的集成激活系统，所述激活系统包括具有第一和第二输入并且具有耦合到所述急性使用装置的输出的切换电路，耦合到所述第一输入并配置的门控元件 从电源到开关电路的栅极电力，以及耦合到开关电路的第二输入的感测元件。 感测元件被配置为感测激活条件，启用开关电路的操作间隔，并且在激活条件期间将信号发送到开关电路。 开关电路被配置为在接收到来自感测元件的预定数量的信号时将功率传送到急用设备。
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19.发明授权Implantable medical device controlled by a non-invasive physiological data measurement device 失效由非侵入性生理数据测量装置控制的可植入医疗装置公开(公告)号：US06922592B2
公开(公告)日：2005-07-26
申请号：US09825909
申请日：2001-04-04
CPC分类号： A61N1/37235 , A61B5/0031 , A61B5/02427 , A61B5/02438 , A61B5/0261 , A61B5/6807 , A61B5/6824 , A61B5/6826 , A61B5/6838 , A61N1/08 , A61N1/37252
摘要： The operational and functional aspects of one or more IMDs is controlled by physiological data acquired from an external device. Various externally deployed devices collect vital signals for transmission to the IMD. Upon receipt of the signals the IMD cooperatively modifies therapy and diagnostic procedures to be substantially compliant with the received signals. Further, the IMD may store some of the signals for future follow-up or patient data management as needed.
摘要翻译： 一个或多个IMD的操作和功能方面由从外部设备获取的生理数据控制。 各种外部部署的设备收集重要信号以传输到IMD。 在接收到信号后，IMD协调地将治疗和诊断程序修改为基本上符合所接收的信号。 此外，IMD可以根据需要存储一些信号用于将来的随访或患者数据管理。
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公开(公告)号：US06470212B1
公开(公告)日：2002-10-22
申请号：US09529292
申请日：2000-04-11
IPC分类号： A61N108
CPC分类号： A61N1/3785 , A61N1/08
摘要： A system for and method of providing power to an implanted medical device within a patient is disclosed. The system (250) includes a first (262) and a second heat conduit (264) positioned within the patient. A thermoelectric device (252) is connected to the first and second heat conduits for thermally converting the temperature difference between the conduits to a voltage. A DC-DC converter (254) is connected to the thermoelectric element and increases the voltage. A storage element (256) is connected to the DC-DC converter-for receiving the increased voltage. The storage element is also connected to the implanted medical device (258), thereby providing power to the implanted medical device.
摘要翻译： 公开了一种向患者内的植入医疗装置提供电力的系统和方法。 系统（250）包括位于患者体内的第一（262）和第二热导管（264）。 热电装置（252）连接到第一和第二导热管，用于将导管之间的温差热转换成电压。 DC-DC转换器（254）连接到热电元件并增加电压。 存储元件（256）连接到DC-DC转换器，用于接收增加的电压。 存储元件还连接到植入医疗设备（258），从而向植入的医疗设备提供电力。
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