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公开(公告)号：US11571349B2
公开(公告)日：2023-02-07
申请号：US16499953
申请日：2019-03-20
摘要： The herein described Adaptive Ergonomic Positioning device (“AEPD”) relates generally to the field of surgery and other medical or healthcare procedures. The AEPD can be adapted for use with most standard surgical tables and surgical chairs where the patient must be positioned prone during a particular procedure. The AEPD may also be used for certain procedures where the patient may be positioned supine. The AEPD support assemblies are highly adjustable and deliver improved ergonomics for both patients and providers. Patients of different morphology can be comfortably positioned in prone with their head and neck in a neutral position, and shoulders in a forward flexed, slightly internally rotated position. The AEPD can be adjusted to accommodate patients with neck and shoulder mobility restrictions, without any effect on provider accessibility to the surgical or treatment site.
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公开(公告)号：US09816318B2
公开(公告)日：2017-11-14
申请号：US14966559
申请日：2015-12-11
申请人： David A. Johnson
发明人： David A. Johnson
摘要： A ladder assembly for a work vehicle comprises a deck affixed horizontally just below an entry door of the cab. A yoke is pivotally joined to a support member of the deck for rotation about a vertical axis below the deck surface. The yoke has a pair of arms pivotally joined to an upper end of a ladder structure for allowing rotation of the ladder about a horizontal axis. A turnbuckle is coupled between the support structure of the deck and one stringer of the ladder while a mechanical actuator is operatively coupled to the ladder's other stringer and to an arm of the yoke to which the other stringer is attached. Operation of the mechanical actuator moves the ladder reciprocally between a use position and stowed position where the stowed position is parallel to and immediately below the deck.
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公开(公告)号：US09468402B2
公开(公告)日：2016-10-18
申请号：US13991113
申请日：2011-12-01
申请人： Peter A. Petillo , George S. Wilson , Judy Z. Wu , Mark L. Richter , David A. Johnson , Daniel V. Aillon
发明人： Peter A. Petillo , George S. Wilson , Judy Z. Wu , Mark L. Richter , David A. Johnson , Daniel V. Aillon
IPC分类号： A61B5/05 , A61B5/1486 , A61B5/145 , C25D7/00
CPC分类号： A61B5/14865 , A61B5/14532 , A61B2562/12 , C25D7/00
摘要： A biosensor system comprises a capillary substrate, conductive electrode, and a plurality of nanoparticles having an enzyme deposited thereon formed in a cavity at one end of the capillary substrate. The substrate may have an optional reinforcing layer (which may be conductive or non-conductive) and optional insulating layer thereon. A cannula having an optional conductive layer, insulating layer, and reference electrode may also form part of the system.
摘要翻译： 生物传感器系统包括毛细管基底，导电电极和在毛细管基底的一端形成在腔中的沉积有酶的多个纳米颗粒。 衬底可以具有可选的增强层（其可以是导电的或不导电的）和其上的可选的绝缘层。 具有可选导电层，绝缘层和参考电极的插管也可以形成系统的一部分。
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公开(公告)号：US08575340B2
公开(公告)日：2013-11-05
申请号：US13578008
申请日：2011-02-08
IPC分类号： A61K31/52 , C07D473/18 , A61P31/00 , A61P35/00 , A61P37/08 , A61P29/00 , A61P37/04 , A61P11/06
CPC分类号： C07D473/18 , C07D473/16
摘要： The present invention relates to compounds of formula (I): wherein; R1 represents hydrogen or C1-3alkyl; n is an integer having a value of 1 to 5; X represents O or NH; Y represents C or N; or a pharmaceutically acceptable salt thereof, have been shown to be inducers of human interferon and may possess an improved profile with respect to known inducers of human interferon, for example enhanced potency. The compounds of the invention may therefore be useful in the treatment of various disorders, in particular the treatment of infectious diseases, cancer, allergic diseases and other inflammatory conditions, and their use as vaccine adjuvants.
摘要翻译： 本发明涉及式（I）的化合物：其中： R1代表氢或C1-3烷基; n为1〜5的整数， X表示O或NH; Y表示C或N; 已经显示其是人类干扰素的诱导剂，并且相对于人干扰素的已知诱导剂可能具有改进的特征，例如增强的效力。 因此，本发明的化合物可用于治疗各种疾病，特别是治疗感染性疾病，癌症，过敏性疾病和其它炎性病症，以及它们作为疫苗佐剂的用途。
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公开(公告)号：US20120315291A1
公开(公告)日：2012-12-13
申请号：US13578008
申请日：2011-02-08
IPC分类号： A61K31/52 , A61P31/00 , A61P35/00 , A61P11/06 , A61P29/00 , A61K39/00 , A61P37/04 , C07D473/18 , A61P37/08
CPC分类号： C07D473/18 , C07D473/16
摘要： The present invention relates to compounds of formula (I): wherein; R1 represents hydrogen or C1-3alkyl; n is an integer having a value of 1 to 5; X represents O or NH; Y represents C or N; or a pharmaceutically acceptable salt thereof, have been shown to be inducers of human interferon and may possess an improved profile with respect to known inducers of human interferon, for example enhanced potency. The compounds of the invention may therefore be useful in the treatment of various disorders, in particular the treatment of infectious diseases, cancer, allergic diseases and other inflammatory conditions, and their use as vaccine adjuvants.
摘要翻译： 本发明涉及式（I）的化合物：其中： R1代表氢或C1-3烷基; n为1〜5的整数， X表示O或NH; Y表示C或N; 已经显示其是人类干扰素的诱导剂，并且相对于人干扰素的已知诱导剂可能具有改进的特征，例如增强的效力。 因此，本发明的化合物可用于治疗各种疾病，特别是治疗感染性疾病，癌症，过敏性疾病和其它炎性病症，以及它们作为疫苗佐剂的用途。
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公开(公告)号：US20120247653A1
公开(公告)日：2012-10-04
申请号：US13454982
申请日：2012-04-24
申请人： David A. Johnson , James Pritts
发明人： David A. Johnson , James Pritts
IPC分类号： B29D11/00
CPC分类号： G02B5/305 , G02B27/2228 , G02C7/12 , Y10T156/1026
摘要： Curved lenses configured to decode three dimensional content and method of fabricating the same. The lenses comprise a polyvinylalcohol polarizer film or similar type of material laminated with triacetate or similar type material on one or both sides, wherein the polarizer film has a polarizing efficiency equal to or exceeding 99% and a transmittance percentage equal to or exceeding 35% and a retarder film (e.g., norbornene copolymer resin) laminated on a front surface of the polyvinylalcohol polarizer film laminated with triacetate and aligned to produce a desired circular polarization responsive to specified retardation wavelengths. Thermoforming and press polishing techniques may be used to fabricate/curve the blanks into lenses. The lenses (optical elements) may be used in an injection molding process to add thickness.
摘要翻译： 构造成解码三维内容的弯曲透镜及其制造方法。 透镜包括在一侧或两侧上与三乙酸酯或类似材料层压的聚乙烯醇偏光膜或类似类型的材料，其中偏振膜具有等于或超过99％的偏振效率和等于或超过35％的透光率百分比， 层叠在与三乙酸酯层叠的聚乙烯醇偏光膜的前表面上的缓凝剂膜（例如降冰片烯共聚物树脂），并对准以响应于指定的延迟波长产生期望的圆形极化。 热成型和压制抛光技术可用于制造/将坯料曲线成镜片。 透镜（光学元件）可以用于注射成型工艺以增加厚度。
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公开(公告)号：US20120238912A1
公开(公告)日：2012-09-20
申请号：US13050053
申请日：2011-03-17
申请人： Parimal G. Rajkondawar , Roger K. Erdman , David A. Johnson , William S. Nelson , Paul D. Thompson
发明人： Parimal G. Rajkondawar , Roger K. Erdman , David A. Johnson , William S. Nelson , Paul D. Thompson
IPC分类号： A61B5/103
CPC分类号： A61D17/002 , A01K11/006 , A01K29/005 , A61B5/0002
摘要： In certain embodiments, a method for estrus detection includes storing location information associated with a dairy livestock. The stored location information includes a coordinate location of the dairy livestock within a free stall pen at each of a plurality of times during a time period. The method further includes determining, based on at least a portion of the stored location information, one or more movement parameters associated with the dairy livestock. The method further includes determining, based on one or more movement parameters associated with the dairy livestock, whether the dairy livestock is likely to be in estrus.
摘要翻译： 在某些实施例中，一种用于发情检测的方法包括存储与奶牛家畜相关联的位置信息。 所存储的位置信息包括在一段时间段内的多个时间段内的每个自由档位笔中的奶牛家畜的坐标位置。 该方法还包括基于存储的位置信息的至少一部分来确定与乳品牲畜相关联的一个或多个运动参数。 所述方法还包括基于与所述奶牛家畜相关联的一个或多个运动参数来确定所述乳品牲畜是否可能处于发情期。
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18.发明申请公开(公告)号：US20120234245A1
公开(公告)日：2012-09-20
申请号：US13050096
申请日：2011-03-17
申请人： Parimal G. Rajkondawar , Roger K. Erdman , David A. Johnson , William S. Nelson , Paul D. Thompson , Gary C. Steingraber
发明人： Parimal G. Rajkondawar , Roger K. Erdman , David A. Johnson , William S. Nelson , Paul D. Thompson , Gary C. Steingraber
CPC分类号： A01K1/12 , A01J5/00 , A01J5/007 , A01J7/00 , A01K11/006 , A01K29/005 , G05B15/02
摘要： In certain embodiments, a method for milking stall assignment includes storing first location information associated with a dairy livestock, the first location information comprising a coordinate location of the dairy livestock within a milking parlor at a first time. The method further includes comparing the stored first location information associated with the dairy livestock with an area associated with each of a plurality of milking stalls of the milking parlor to identify a milking stall in which the dairy cow is located at the first time and assigning the dairy livestock to the milking stall in which the dairy cow is located at the first time such that data associated with milking of the dairy livestock may be associated with the dairy cow.
摘要翻译： 在某些实施例中，一种用于挤奶失速分配的方法包括存储与奶牛家畜相关联的第一位置信息，第一位置信息在第一时间包括挤奶室内的奶牛家畜的坐标位置。 该方法还包括将与乳品牲畜相关联的存储的第一位置信息与与挤奶室的多个挤奶档位中的每一个相关联的区域进行比较，以便在第一时间识别奶牛位于其中的挤奶档位， 将奶牛的牲畜首次置于奶牛所在的挤奶摊位，使得与奶牛的挤奶有关的数据可能与奶牛相关联。
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公开(公告)号：US20120029756A1
公开(公告)日：2012-02-02
申请号：US12845362
申请日：2010-07-28
申请人： David A. Johnson , Monte A. Dickson
发明人： David A. Johnson , Monte A. Dickson
IPC分类号： G05D1/00
CPC分类号： G05D1/0265 , A01D34/008 , G05D1/0225
摘要： A robotic mower boundary coverage system includes a vehicle control unit on the robotic mower commanding a traction drive system to drive the robotic mower at a specified yaw angle with respect to a boundary wire, and a boundary sensor on the robotic mower signaling the distance between the boundary wire and the vehicle control unit. The vehicle control unit alternates commands to direct the traction drive system toward and away from the boundary wire based on the distance of the robotic mower to the boundary wire.
摘要翻译： 机器人割草机边界覆盖系统包括机器人割草机上的车辆控制单元，其指示牵引驱动系统相对于边界线以指定的偏转角度驱动机器人割草机;以及机器人割草机上的边界传感器， 边界线和车辆控制单元。 车辆控制单元基于机器人割草机与边界线的距离来交替命令以将牵引驱动系统引向和远离边界线。
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20.发明授权Processes for the production of aminoalkyl glucosaminide phosphate and disaccharide immunoeffectors, and intermediates therefor 有权用于生产氨基烷基氨基葡糖苷磷酸酯和二糖免疫机制的方法及其中间体公开(公告)号：US07960523B2
公开(公告)日：2011-06-14
申请号：US11867605
申请日：2007-10-04
申请人： David A. Johnson
发明人： David A. Johnson
IPC分类号： C08B37/00
摘要： This invention relates to processes for production of alkylamino glucosaminide phosphate compounds, and of disaccharide compounds, including various novel intermediates and intermediate processes. In one aspect, glycosyl halides are produced by reaction of an O-silyl glycoside with a dihalomethyl alkyl ether.
摘要翻译： 本发明涉及生产烷基氨基葡糖苷磷酸酯化合物的方法，以及二糖化合物的制备方法，包括各种新型中间体和中间体方法。 一方面，通过O-甲硅烷基糖苷与二卤代甲基烷基醚的反应制备糖基卤化物。
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