公开(公告)号：US07041112B2

公开(公告)日：2006-05-09

申请号：US10842998

申请日：2004-05-11

申请人： Jaime Vargas ,  Tenny Chang ,  David Bombard

发明人： Jaime Vargas ,  Tenny Chang ,  David Bombard

IPC分类号： A61B17/08

CPC分类号： A61B17/11 ,  A61B17/0218 ,  A61B2017/1107 ,  A61B2017/1135

摘要： A method for tensioning incisions made in a target vessel during an anastomosis procedure is provided. After an incision is made in a target vessel, incision tensioners are placed within the incision in order to tension the incision. The incision is tensioned when the incision tensioners are pulled taut in order to stretch the incision to a predetermined length or a predetermined force. The tensioners allow for proper grafting of a graft vessel to the target vessel in an end to side anastomosis. In addition, the incision tensioners allow the incision to have a known geometry, thereby allowing precise grafting of the graft vessel to the target vessel during the anastomosis procedure. After the incision is tensioned, the graft vessel is grafted to the target vessel using clips, sutures, staples or other anastomosis devices. One example of anastomosis clips are configured to capture the graft vessel and the target vessel such that the graft vessel grafts with the target vessel.

摘要翻译： 提供了一种在吻合手术过程中在目标血管中张紧切口的方法。 在目标血管中进行切口后，将切口张紧器置于切口内以拉紧切口。 当将切口张紧器拉紧拉紧以将切口拉伸至预定长度或预定力时，切口被张紧。 张紧器允许在端对侧吻合中将移植物容器适当地接合到靶容器。 此外，切口张紧器允许切口具有已知的几何形状，从而允许在吻合过程期间移植物容器到目标血管的精确移植。 在切口被张紧之后，使用夹子，缝线，缝钉或其它吻合装置将移植血管移植到靶容器。 吻合夹的一个实例被配置成捕获移植物容器和靶容器，使得移植血管与靶血管移植。

公开(公告)号：US06786862B2

公开(公告)日：2004-09-07

申请号：US10367175

申请日：2003-02-14

申请人： Jaime Vargas ,  Ted Bender ,  David Bombard ,  Jeremy Frank

发明人： Jaime Vargas ,  Ted Bender ,  David Bombard ,  Jeremy Frank

IPC分类号： A61F206

CPC分类号： A61F2/062 ,  A61F2/06

摘要： A graft vessel preparation device and a method for using the graft vessel preparation device is provided. The graft vessel preparation device establishes and maintains a critical dimension on a graft vessel which corresponds to a dimension of an anastomosis site on a target vessel. One example of a graft vessel preparation device which prepares a graft vessel for a vascular anastomosis procedure includes a parallelogram linkage, a first spreader arm and a second spreader arm. The first spreader arm and the second spreader arm mount on opposing members of the parallelogram linkage in a parallel configuration. The spreader arms are configured in order to allow the placement of an end of a graft vessel over the spreader arms. The spreader arms are also configured to separate within an interior of the graft vessel once the graft vessel is placed over the spreader arms in order to establish a critical dimension. The critical dimension is established using a critical dimension locator. The critical dimension locator allows for precise grafting of the graft vessel to a target vessel during the vascular anastomosis procedure.

摘要翻译： 提供了移植血管制备装置和使用移植血管制备装置的方法。 移植血管制备装置在对应于靶血管上的吻合部位的尺寸的移植物容器上建立和维持临界尺寸。 准备用于血管吻合术的移植血管的移植血管制备装置的一个实例包括平行四边形连杆，第一扩张臂和第二扩张臂。 第一吊架臂和第二吊架臂以并联结构安装在平行四边形连杆的相对构件上。 构造吊具臂以便允许将移植物容器的末端放置在扩展臂上。 一旦将移植物容器放置在扩张器臂上以便建立临界尺寸，扩展臂也被构造成在移植脉管内部分离。 关键维度是使用关键维度定位器建立的。 关键维度定位器允许在血管吻合手术期间将移植物容器精确移植到靶血管。

公开(公告)号：US06554764B1

公开(公告)日：2003-04-29

申请号：US09712044

申请日：2000-11-13

申请人： Jaime Vargas ,  Ted Bender ,  David Bombard ,  Jeremy Frank

发明人： Jaime Vargas ,  Ted Bender ,  David Bombard ,  Jeremy Frank

IPC分类号： A61F206

CPC分类号： A61F2/062 ,  A61F2/06

摘要： A graft vessel preparation device and a method for using the graft vessel preparation device is provided. The graft vessel preparation device establishes and maintains a critical dimension on a graft vessel which corresponds to a dimension of an anastomosis site on a target vessel. One example of a graft vessel preparation device which prepares a graft vessel for a vascular anastomosis procedure includes a parallelogram linkage, a first spreader arm and a second spreader arm. The first spreader arm and the second spreader arm mount on opposing members of the parallelogram linkage in a parallel configuration. The spreader arms are configured in order to allow the placement of an end of a graft vessel over the spreader arms. The spreader arms are also configured to separate within an interior of the graft vessel once the graft vessel is placed over the spreader arms in order to establish a critical dimension. The critical dimension is established using a critical dimension locator. The critical dimension locator allows for precise grafting of the graft vessel to a target vessel during the vascular anastomosis procedure.

摘要翻译： 提供了移植血管制备装置和使用移植血管制备装置的方法。 移植血管制备装置在对应于靶血管上的吻合部位的尺寸的移植物容器上建立和维持临界尺寸。 准备用于血管吻合术的移植血管的移植血管制备装置的一个实例包括平行四边形连杆，第一扩张臂和第二扩张臂。 第一吊架臂和第二吊架臂以并联结构安装在平行四边形连杆的相对构件上。 构造吊具臂以便允许将移植物容器的末端放置在扩展臂上。 一旦将移植物容器放置在扩张器臂上以便建立临界尺寸，扩展臂也被构造成在移植脉管内部分离。 关键维度是使用关键维度定位器建立的。 关键维度定位器允许在血管吻合手术期间将移植物容器精确移植到靶血管。

公开(公告)号：US06882880B2

公开(公告)日：2005-04-19

申请号：US10324717

申请日：2002-12-19

申请人： Steven Treppo ,  Alan J. Grodzinsky ,  Emerson Quan ,  Eliot Frank ,  David Bombard ,  David Breslau

发明人： Steven Treppo ,  Alan J. Grodzinsky ,  Emerson Quan ,  Eliot Frank ,  David Bombard ,  David Breslau

IPC分类号： A61B5/05 ,  A61B5/053 ,  A61B5/103

CPC分类号： A61B5/4514 ,  A61B5/05 ,  A61B5/053 ,  A61B5/103 ,  A61B5/4528 ,  A61B5/6847 ,  A61B2562/0209 ,  A61B2562/0261

摘要： The change in tissue impedance due to the change in the extracellular matrix that results from the degradation of cartilage is utilized to detect degradation of articular cartilage. A probe includes electrodes that apply a current to the articular cartilage which results in a current distribution and electric field within the cartilage, along with an associated voltage drop across the electrodes. The amplitude of this voltage drop is then measured and divided by the current applied to determine the tissue impedance. By measuring the impedance of patient tissue and comparing the detected patient impedance to a normal value for the tissue from clinically normal tissue, a determination of whether the patient tissue is degraded, and a determination of the extent of degradation is possible. Preferably, the impedance is measured using a probe with interdigitated electrodes. By changing which electrodes are utilized, the wavelength of the current distribution changes, allowing the probe to image depth dependent focal lesions.

摘要翻译： 利用由软骨降解导致的细胞外基质变化引起的组织阻抗变化来检测关节软骨的降解。 探针包括向关节软骨施加电流的电极，其导致软骨内的电流分布和电场，以及电极两端的相关电压降。 然后测量该电压降的幅度并除以施加的电流以确定组织阻抗。 通过测量患者组织的阻抗并将检测到的患者阻抗与来自临床正常组织的组织的正常值进行比较，确定患者组织是否退化，并确定降解程度是可能的。 优选地，使用具有交错电极的探针来测量阻抗。 通过改变使用哪些电极，电流分布的波长发生变化，允许探针成像深度相关的局灶性病变。

公开(公告)号：US06856834B2

公开(公告)日：2005-02-15

申请号：US10600918

申请日：2003-06-20

申请人： Steven Treppo ,  Alan J. Grodzinsky ,  Emerson Quan ,  Eliot Frank ,  David Bombard ,  David Breslau

发明人： Steven Treppo ,  Alan J. Grodzinsky ,  Emerson Quan ,  Eliot Frank ,  David Bombard ,  David Breslau

IPC分类号： A61B5/05 ,  A61B5/053 ,  A61B5/103

CPC分类号： A61B5/4514 ,  A61B5/05 ,  A61B5/053 ,  A61B5/103 ,  A61B5/4528 ,  A61B5/6847 ,  A61B2562/0209 ,  A61B2562/0261

摘要： The change in tissue impedance due to the change in the extracellular matrix that results from the degradation of cartilage is utilized to detect degradation of articular cartilage. A probe comprising electrodes is applies a current to the articular cartilage which results in a current distribution and electric field within the cartilage, along with an associated voltage drop across the electrodes. The amplitude of this voltage drop is then measured and divided by the current applied to determine the tissue impedance. By measuring the impedance of patient tissue and comparing the detected patient impedance to a normal value for the tissue from clinically normal tissue, a determination of whether the patient tissue is degraded and the extent of degradation is possible. Preferably, the impedance is measured using a probe with interdigitated electrodes. By changing which electrodes are utilized, the wavelength of the current distribution changes, allowing the probe to image depth dependent focal lesions.

摘要翻译： 利用由软骨降解导致的细胞外基质变化引起的组织阻抗变化来检测关节软骨的降解。 包括电极的探针向关节软骨施加电流，其导致软骨内的电流分布和电场以及电极两端的相关电压降。 然后测量该电压降的幅度并除以施加的电流以确定组织阻抗。 通过测量患者组织的阻抗并将检测到的患者阻抗与来自临床正常组织的组织的正常值进行比较，确定患者组织是否劣化并且降解程度是可能的。 优选地，使用具有交错电极的探针来测量阻抗。 通过改变使用哪些电极，电流分布的波长发生变化，允许探针成像深度相关的局灶性病变。

公开(公告)号：US06735468B2

公开(公告)日：2004-05-11

申请号：US09776254

申请日：2001-02-02

申请人： Steven Treppo ,  Alan J. Grodzinsky ,  Emerson Quan ,  Eliot Frank ,  David Bombard ,  David Breslau

发明人： Steven Treppo ,  Alan J. Grodzinsky ,  Emerson Quan ,  Eliot Frank ,  David Bombard ,  David Breslau

IPC分类号： A61B505

CPC分类号： A61B5/4514 ,  A61B5/05 ,  A61B5/053 ,  A61B5/103 ,  A61B5/4528 ,  A61B5/6847 ,  A61B2562/0209 ,  A61B2562/0261

摘要： The change in tissue impedance due to the change in the extracellular matrix that results from the degradation of cartilage is utilized to detect degradation of articular cartilage. A probe applies a current to the articular cartilage which results in a current distribution and electric field within the cartilage, along with an associated voltage drop across the electrodes. The amplitude of this voltage drop is then measured and divided by the current applied to determine the tissue impedance. By measuring the impedance of patient tissue and comparing the detected patient impedance to a normal value for the tissue from clinically normal tissue, a determination of whether the patient tissue is degraded and the extent of degradation is possible. Preferably, the impedance is measured using a probe with interdigitated electrodes. By changing which electrodes are utilized, the wavelength of the current distribution changes, allowing the probe to image depth dependent focal lesions.

摘要翻译： 利用由软骨降解导致的细胞外基质变化引起的组织阻抗变化来检测关节软骨的降解。 探针将电流施加到关节软骨上，导致软骨内的电流分布和电场以及电极两端的相关电压降。 然后测量该电压降的幅度并除以施加的电流以确定组织阻抗。 通过测量患者组织的阻抗并将检测到的患者阻抗与来自临床正常组织的组织的正常值进行比较，确定患者组织是否劣化并且降解程度是可能的。 优选地，使用具有交错电极的探针来测量阻抗。 通过改变使用哪些电极，电流分布的波长发生变化，允许探针成像深度相关的局灶性病变。