公开(公告)号：US20060294612A1

公开(公告)日：2006-12-28

申请号：US11278477

申请日：2006-04-03

Applicant: David Lewin ,  Timothy Stewart

Inventor： David Lewin ,  Timothy Stewart

IPC: C12Q1/68 ,  G01N33/567 ,  A01K67/027 ,  C07H21/04 ,  C12P21/06 ,  A61K39/395 ,  C07K14/72 ,  C07K16/28

CPC classification number: C07K14/5759 ,  A61K38/00 ,  C07K14/705

Abstract: A novel G-protein coupled receptor-like retinoic acid induced molecule was identified as being differentially expressed (GPCR-like RAIG1) in an animal model of fasting and feeding. Compositions and methods pertaining to treatment and diagnosis of various metabolic disorders, such as cachexia and obesity.

Abstract translation: 在禁食和喂食的动物模型中，鉴定出新型G蛋白偶联受体样视黄酸诱导分子为差异表达（GPCR样RAIG1）。 关于治疗和诊断各种代谢疾病如恶病质和肥胖症的组合物和方法。

公开(公告)号：US20050074767A1

公开(公告)日：2005-04-07

申请号：US10608865

申请日：2003-06-27

Applicant: David Lewin ,  Timothy Stewart

Inventor： David Lewin ,  Timothy Stewart

IPC: C12N15/09 ,  A61K31/7088 ,  A61K38/00 ,  A61K39/395 ,  A61K45/00 ,  A61K48/00 ,  A61P3/04 ,  C07K14/00 ,  C07K14/47 ,  C07K14/575 ,  C07K14/665 ,  C07K14/805 ,  C07K16/18 ,  C12M1/00 ,  C12M1/34 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/64 ,  C12Q1/02 ,  C12Q1/68

CPC classification number: C07K14/665 ,  A61K38/00 ,  A61K2123/00 ,  C07K14/57554 ,  C07K14/5759 ,  C07K14/805 ,  C12N9/6424 ,  C12Q1/6883 ,  C12Q2600/158 ,  C12Y304/21094

Abstract: The instant invention is concerned with genes associated with obesity. Additionally, the invention provides methods of using the differential expression of these genes associated with obesity to diagnose and treat obesity, as well as to screen for compounds useful for treating obesity.

Abstract translation: 本发明涉及与肥胖相关的基因。 另外，本发明提供了使用与肥胖相关的这些基因的差异表达来诊断和治疗肥胖症以及筛选可用于治疗肥胖症的化合物的方法。