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    BIOPROSTHETIC HEART VALVES HAVING ADAPTIVE SEALS TO MINIMIZE PARAVALVULAR LEAKAGE
    11.
    发明申请
    BIOPROSTHETIC HEART VALVES HAVING ADAPTIVE SEALS TO MINIMIZE PARAVALVULAR LEAKAGE 审中-公开
    具有适应性密封件的生物心脏瓣膜，以最小化旁路泄漏

    公开(公告)号：US20150122687A1

    公开(公告)日：2015-05-07

    申请号：US14533922

    申请日：2014-11-05

    Applicant: Edwards Lifesciences Corporation

    Inventor： Qinggang Zeng ,  Chacphet Limsakoune ,  Diana E. Ko ,  Christina M. Aguila

    IPC: A61B19/02 ,  A61F2/24

    CPC classification number: A61B50/30 ,  A61B50/33 ,  A61B2050/002 ,  A61F2/0095 ,  A61F2/2412 ,  A61F2/2415 ,  A61F2/2418 ,  A61F2250/0069

    Abstract: A packaged bioprosthetic heart valve comprising a bioprosthetic heart valve, an adaptive seal and a package. The bioprosthetic heart valve comprises an at least partially dehydrated biological tissue leaflet structure coupled to a supporting frame. The bioprosthetic heart valve has a periphery, an inflow portion, and an outflow portion. The adaptive seal is coupled to the bioprosthetic heart valve around at least a portion of the periphery. The adaptive seal comprises an expandable material that expands after exposure to an initiating condition. The bioprosthetic heart valve and the adaptive seal is stored and contained within the package, which does not contain a liquid storage solution in contact with the bioprosthetic heart valve and the adaptive seal.

    Abstract translation: 包装的生物假体心脏瓣膜包括生物假体心脏瓣膜，自适应密封和包装。 生物假体心脏瓣膜包括联接到支撑框架的至少部分脱水的生物组织小叶结构。 生物假体心脏瓣膜具有周边，流入部分和流出部分。 自适应密封件围绕周边的至少一部分耦合到生物假体心脏瓣膜。 自适应密封件包括在暴露于起始条件之后膨胀的可膨胀材料。 生物假体心脏瓣膜和自适应密封件被储存并包含在包装内，其不包含与生物假体心脏瓣膜和自适应密封接触的液体储存溶液。

    CONFORMAL EXPANSION OF PROSTHETIC DEVICES TO ANATOMICAL SHAPES
    12.
    发明申请
    CONFORMAL EXPANSION OF PROSTHETIC DEVICES TO ANATOMICAL SHAPES 有权
    将前置装置扩展到解剖形状

    公开(公告)号：US20140081389A1

    公开(公告)日：2014-03-20

    申请号：US14089723

    申请日：2013-11-25

    Applicant: Edwards Lifesciences Corporation

    Inventor： Mark Chau ,  Travis Oba ,  Tammy Huntley ,  Qinggang Zeng ,  August R. Yambao ,  Rafael Pintor

    IPC: A61F2/24

    CPC classification number: A61F2/2433 ,  A61F2/2418 ,  A61F2/243 ,  A61F2220/0008 ,  A61F2230/0054 ,  A61F2250/0003

    Abstract: A system for expanding a device in a conduit or orifice of a human body includes an expansion device that is movable from a first configuration to a second configuration. External surfaces of the expansion device can collectively have a non-cylindrical cross-section relative to a main axis of the expansion device, such that the external surfaces of the expansion device generally conform to the anatomical shape of the conduit or orifice when the expansion device is in the second configuration.

    Abstract translation: 一种用于在人体的管道或孔中扩张装置的系统包括可从第一构型移动到第二构造的膨胀装置。 膨胀装置的外表面可以相对于膨胀装置的主轴线共同具有非圆柱形横截面，使得当膨胀装置的膨胀装置的外表面大致符合导管或孔口的解剖形状时 处于第二个配置。

    ADJUSTABLE DEVICE FOR TREATING HEART VALVE REGURGITATION
    13.
    发明申请
    ADJUSTABLE DEVICE FOR TREATING HEART VALVE REGURGITATION 有权

    公开(公告)号：US20250152357A1

    公开(公告)日：2025-05-15

    申请号：US19023531

    申请日：2025-01-16

    Applicant: EDWARDS LIFESCIENCES CORPORATION

    Inventor： Qinggang Zeng

    IPC: A61F2/24

    Abstract: A prosthetic device for treating a native valve of a heart includes a sealing element and an anchoring element. The sealing element comprises a braided mesh material. The sealing element is dimensioned to be deployed at the native valve. The sealing element is configured to both be radially expanded and radially reduced while at a position between the native valve leaflets. The anchoring element is coupled to the sealing element and is configured to support the sealing element between the native valve leaflets.

    Methods of identifying and replacing implanted heart valves
    15.
    发明授权
    Methods of identifying and replacing implanted heart valves 有权

    公开(公告)号：US11154394B2

    公开(公告)日：2021-10-26

    申请号：US16270849

    申请日：2019-02-08

    Applicant: Edwards Lifesciences Corporation

    Inventor： Jessica Guttenberg ,  Da-Yu Chang ,  Derrick Johnson ,  Brian S. Conklin ,  Qinggang Zeng ,  Myron Howanec, Jr. ,  Grace Myong Kim

    IPC: A61F2/24

    Abstract: A prosthetic heart valve configured to replace a native heart valve and for post-implant expansion and having a valve-type indicator thereon visible from outside the body post-implant. The indicator communicates information about the valve, such as the size or orifice diameter of the valve, and/or that the valve has the capacity for post-implant expansion. The indicator can be an alphanumeric symbol or other symbol or combination of symbols that represent information about the characteristics of the valve such as the valve size. The capacity for post-implant expansion facilitates a valve-in-valve procedure, where the valve-type indicator conveys information to the surgeon about whether the implanted valve is suitable for the procedure and informs the choice of the secondary valve.

    HYBRID HEART VALVES ADAPTED FOR POST-IMPLANT EXPANSION
    16.
    发明申请
    HYBRID HEART VALVES ADAPTED FOR POST-IMPLANT EXPANSION 审中-公开

    公开(公告)号：US20200323633A1

    公开(公告)日：2020-10-15

    申请号：US16914255

    申请日：2020-06-26

    Applicant: Edwards Lifesciences Corporation

    Inventor： Brian S. Conklin ,  Qinggang Zeng

    IPC: A61F2/24

    Abstract: A hybrid prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be expanded post implant in order to receive and/or support an expandable prosthetic heart valve therein (a valve-in-valve procedure). The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander. An inflow stent frame is expandable for anchoring the valve in place, and may have an outflow end that is collapsible for delivery and expandable post-implant to facilitate a valve-in-valve procedure.

    AXISYMMETRIC ADJUSTABLE DEVICE FOR TREATING MITRAL REGURGITATION
    17.
    发明申请
    AXISYMMETRIC ADJUSTABLE DEVICE FOR TREATING MITRAL REGURGITATION 审中-公开

    公开(公告)号：US20190076247A1

    公开(公告)日：2019-03-14

    申请号：US16121507

    申请日：2018-09-04

    Applicant: Edwards Lifesciences Corporation

    Inventor： Qinggang Zeng

    IPC: A61F2/24

    Abstract: The invention is a prosthetic device for improving function of a mitral valve. The device includes an adjustable and axisymmetrical-or-elongated sealing member configured for positioning between mitral valve leaflets. The device also includes an expandable anchor frame configured to be positioned within one or more heart chambers, for maintaining the sealing member at a desired position and size/shape between valve leaflets. The sealing member reduces mitral regurgitation be filling the gap that can occur between opposing leaflets of a damaged mitral valve, thus restoring proper mitral valve closure.

    Systems for quickly delivering a prosthetic heart valve
    20.
    发明授权
    Systems for quickly delivering a prosthetic heart valve 有权
    用于快速输送假体心脏瓣膜的系统

    公开(公告)号：US09561100B2

    公开(公告)日：2017-02-07

    申请号：US14684267

    申请日：2015-04-10

    Applicant: Edwards Lifesciences Corporation

    Inventor： Rafael Pintor ,  Mark Chau ,  Travis Oba ,  August R. Yambao ,  Louis A. Campbell ,  Tammy Huntley ,  Qinggang Zeng ,  Carey L. Cristea ,  Faisal Kalam

    IPC: A61F2/24

    CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2/243 ,  A61F2/2433 ,  A61F2220/0016 ,  A61F2220/0025 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2220/0083 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/0069 ,  A61F2230/0078 ,  A61F2250/006

    Abstract: A heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve has a base stent that is deployed at a treatment site, and a valve component configured to quickly connect to the base stent. The base stent may take the form of a self- or balloon-expandable stent that expands outward against the native valve with or without leaflet excision. The valve component has a non-expandable prosthetic valve and a self- or balloon-expandable coupling stent for attachment to the base stent, thereby fixing the position of the valve component relative to the base stent. The prosthetic valve may be a commercially available to valve with a sewing ring and the coupling stent attaches to the sewing ring. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment. A catheter-based system and method for deployment is provided.

    Abstract translation: 提供了可以在手术过程中快速且容易地植入的心脏瓣膜假体。 假体瓣膜具有部署在治疗部位的基部支架和构造成快速连接到基部支架的阀部件。 基底支架可以采取自体或球囊扩张的支架的形式，其在具有或不具有小叶切除的情况下相对于天然瓣膜向外扩张。 阀部件具有不可扩张的假体瓣膜和用于附接到基底支架的自支撑或球囊扩张的联接支架，由此固定阀部件相对于基底支架的位置。 人造瓣膜可以是市售的，具有缝合环的阀门，并且联接支架附接到缝合环。 该系统特别适用于在常规开心手术环境中快速部署心脏瓣膜。 提供了基于导管的系统和部署方法。

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