公开(公告)号：US12144730B2

公开(公告)日：2024-11-19

申请号：US17653843

申请日：2022-03-07

Applicant: Edwards Lifesciences Corporation

Inventor： Derrick Johnson ,  Van Huynh ,  Qinggang Zeng

IPC: A61F2/24

Abstract: A prosthetic heart valve for implant in a human. The valve includes a wireform with undulating inflow cusps and outflow commissure posts to which flexible leaflets attach and coapt in a flow area. Each leaflet may drape over the top of the wireform in the cusp area, but have tabs that each extend underneath the wireform at the commissure posts to be secured along with a tab of an adjacent leaflet. The prosthetic heart valve may also be a dual-wire wireform, with the leaflets sandwiched therebetween. One wireform may be larger than the other, with the leaflets extending over the smaller wireform. The smaller wireform may have commissures that bend radially outward from the larger wireform to provide structure to which the leaflet tabs attach.

公开(公告)号：US20230380963A1

公开(公告)日：2023-11-30

申请号：US18231367

申请日：2023-08-08

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Yevgeniy Davidovich Kaufman ,  Qinggang Zeng ,  Matthew A. Peterson ,  Kevin M. Golemo ,  Tejler Javier Gasga ,  Eric Robert Dixon

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2250/0029 ,  A61F2220/0008 ,  A61F2230/0017 ,  A61F2/90

Abstract: Disclosed are embodiments of replacement heart valves. Embodiments may include a collapsible and expandable frame comprising rows of cells. The frame may include a plurality of axial connection portions extending between top ends and bottom ends of the cells, wherein each axial connecting portion is shaped to bend for accommodating temporary changes in cell height during non-uniform compression of the replacement heart valve. Frames having these features are advantageous when advancing a replacement heart valve through a funnel-shaped compression tool. The axial connection portions are sufficiently flexible to accommodate changes in frame shapes during compression while also being sufficiently resilient for enhancing the structural integrity of the frame in the fully deployed state. The replacement heart valves are preferably dual-frame heart valves, wherein the axial connection portions form a portion of an inner frame and wherein an outer frame is provided for engaging tissue and forming a seal.

公开(公告)号：US20230084393A1

公开(公告)日：2023-03-16

申请号：US18056691

申请日：2022-11-17

Applicant: Edwards Lifesciences Corporation

Inventor： Rafael Pintor ,  Mark Chau ,  Travis Zenyo Oba ,  August R. Yambao ,  Louis A. Campbell ,  Tammy Huntley ,  Qinggang Zeng ,  Carey L. Cristea ,  Faisal Kalam

IPC: A61F2/24

Abstract: A heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve has a base stent that is deployed at a treatment site, and a valve component configured to quickly connect to the base stent. The base stent may take the form of a self- or balloon-expandable stent that expands outward against the native valve with or without leaflet excision. The valve component has a non-expandable prosthetic valve and a self- or balloon-expandable coupling stent for attachment to the base stent, thereby fixing the position of the valve component relative to the base stent. The prosthetic valve may be a commercially available to valve with a sewing ring and the coupling stent attaches to the sewing ring. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment. A catheter-based system and method for deployment is provided.

公开(公告)号：US11266499B2

公开(公告)日：2022-03-08

申请号：US15591915

申请日：2017-05-10

Applicant: Edwards Lifesciences Corporation

Inventor： Derrick Johnson ,  Van Huynh ,  Qinggang Zeng

IPC: A61F2/24

Abstract: A prosthetic heart valve for implant in a human. The valve includes a wireform with undulating inflow cusps and outflow commissure posts to which flexible leaflets attach and coapt in a flow area. Each leaflet may drape over the top of the wireform in the cusp area, but have tabs that each extend underneath the wireform at the commissure posts to be secured along with a tab of an adjacent leaflet. The prosthetic heart valve may also be a dual-wire wireform, with the leaflets sandwiched therebetween. One wireform may be larger than the other, with the leaflets extending over the smaller wireform. The smaller wireform may have commissures that bend radially outward from the larger wireform to provide structure to which the leaflet tabs attach.

公开(公告)号：US10799346B2

公开(公告)日：2020-10-13

申请号：US16248706

申请日：2019-01-15

Applicant: Edwards Lifesciences Corporation

Inventor： Rafael Pintor ,  Mark Chau ,  Travis Zenyo Oba ,  August R. Yambao ,  Louis A. Campbell ,  Tammy Huntley ,  Qinggang Zeng ,  Carey L. Cristea ,  Faisal Kalam

IPC: A61F2/24

Abstract: A heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve has a base stent that is deployed at a treatment site, and a valve component configured to quickly connect to the base stent. The base stent may take the form of a self- or balloon-expandable stent that expands outward against the native valve with or without leaflet excision. The valve component has a non-expandable prosthetic valve and a self- or balloon-expandable coupling stent for attachment to the base stent, thereby fixing the position of the valve component relative to the base stent. The prosthetic valve may be a commercially available to valve with a sewing ring and the coupling stent attaches to the sewing ring. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment. A catheter-based system and method for deployment is provided.

公开(公告)号：US20200315795A1

公开(公告)日：2020-10-08

申请号：US16908375

申请日：2020-06-22

Applicant: Edwards Lifesciences Corporation

Inventor： Frederic B. Hodshon ,  Rafael Pintor ,  August R. Yambao ,  Abhishek Gautam ,  Louis A. Campbell ,  Lawrence J. Farhat ,  Tammy Huntley ,  Faisal Kalam ,  Travis Zenyo Oba ,  Qinggang Zeng

IPC: A61F2/24 ,  A61F2/00

Abstract: Packaging for prosthetic heart valves including an assembly for securely retaining a heart valve within ajar and facilitating retrieval therefrom. The assembly includes a packaging sleeve that fits closely within the jar and has a clip structure for securing a valve holder. Contrary to previous designs, in one embodiment the valve holder is directed downward into the jar, and the valve is retained with an inflow end upward. The valve may have flexible leaflets, and a leaflet parting member on the end of the shaft extends through the leaflets and couples with the valve holder. The assembly of the packaging sleeve, valve, and holder can then be removed from the jar and a valve delivery tube connected with the holder, or to the leaflet parting member. The packaging sleeve may be bifurcated into two halves connected at a living hinge to facilitate removal from around the valve/holder subassembly.

公开(公告)号：US20190060072A1

公开(公告)日：2019-02-28

申请号：US16112388

申请日：2018-08-24

Applicant: Edwards Lifesciences Corporation

Inventor： Qinggang Zeng

IPC: A61F2/24

Abstract: The invention is a prosthetic device for improving function of a mitral valve. The device includes a sealing member configured for positioning between mitral valve leaflets. The device also includes an expandable anchor frame configured to be positioned within one or more heart chambers, for maintaining the sealing member at a desired position between valve leaflets. The sealing member reduces mitral regurgitation be filling the gap that can occur between opposing leaflets of a damaged mitral valve, thus restoring proper mitral valve closure.

公开(公告)号：US10130469B2

公开(公告)日：2018-11-20

申请号：US15617906

申请日：2017-06-08

Applicant: Edwards Lifesciences Corporation

Inventor： Jessica Guttenberg ,  Da-Yu Chang ,  Derrick Johnson ,  Brian S. Conklin ,  Qinggang Zeng ,  Myron Howanec ,  Grace Myong Kim

IPC: A61F2/24

Abstract: A prosthetic heart valve configured to replace a native heart valve and for post-implant expansion and having a valve-type indicator thereon visible from outside the body post-implant. The indicator communicates information about the valve, such as the size or orifice diameter of the valve, and/or that the valve has the capacity for post-implant expansion. The indicator can be an alphanumeric symbol or other symbol or combination of symbols that represent information about the characteristics of the valve such as the valve size. The capacity for post-implant expansion facilitates a valve-in-valve procedure, where the valve-type indicator conveys information to the surgeon about whether the implanted valve is suitable for the procedure and informs the choice of the secondary valve.

公开(公告)号：US20180147060A1

公开(公告)日：2018-05-31

申请号：US15880181

申请日：2018-01-25

Applicant: Edwards Lifesciences Corporation

Inventor： Mark Chau ,  Travis Zenyo Oba ,  Tammy Huntley ,  Qinggang Zeng ,  August R. Yambao ,  Rafael Pintor

IPC: A61F2/24

CPC classification number: A61F2/2433 ,  A61F2/2418 ,  A61F2/243 ,  A61F2220/0008 ,  A61F2230/0054 ,  A61F2250/0003

Abstract: A system for expanding a device in a conduit or orifice of a human body includes a balloon member that is movable from a first configuration to a second configuration. External surfaces of the balloon member can collectively have a non-cylindrical cross-section relative to a main axis of the balloon member, such that the external surfaces of the balloon member generally conform to the anatomical shape of the conduit or orifice when the balloon member is in the second configuration.

公开(公告)号：US20160220368A1

公开(公告)日：2016-08-04

申请号：US15097146

申请日：2016-04-12

Applicant: Edwards Lifesciences Corporation

Inventor： Mark Chau ,  Travis Zenyo Oba ,  Tammy Huntley ,  Qinggang Zeng ,  August R. Yambao ,  Rafael Pintor

IPC: A61F2/24

CPC classification number: A61F2/2433 ,  A61F2/2418 ,  A61F2/243 ,  A61F2220/0008 ,  A61F2230/0054 ,  A61F2250/0003

Abstract: A system for expanding a device in a conduit or orifice of a human body includes a balloon member that is movable from a first configuration to a second configuration. External surfaces of the balloon member can collectively have a non-cylindrical cross-section relative to a main axis of the balloon member, such that the external surfaces of the balloon member generally conform to the anatomical shape of the conduit or orifice when the balloon member is in the second configuration.

Abstract translation: 用于在人体的管道或孔中扩张装置的系统包括可从第一构型移动到第二构造的气囊构件。 球囊构件的外表面可以相对于球囊构件的主轴共同具有非圆柱形横截面，使得气囊构件的外表面大体上符合导管或孔口的解剖形状，当球囊构件 处于第二个配置。