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    Unitary quick-connect prosthetic heart valve deployment methods
    14.
    发明授权
    Unitary quick-connect prosthetic heart valve deployment methods 有权
    单一快速连接假体心脏瓣膜部署方法

    公开(公告)号：US08696742B2

    公开(公告)日：2014-04-15

    申请号：US13648906

    申请日：2012-10-10

    Applicant: Edwards Lifesciences Corporation

    Inventor： Rafael Pintor ,  Mark Chau ,  Travis Oba ,  August R. Yambao ,  Louis A. Campbell ,  Tammy Huntley ,  Qinggang Zeng ,  Carey L. Cristea ,  Faisal Kalam

    IPC: A61F2/24

    CPC classification number: A61F2/2427 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2/2439 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/0025 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2220/0083 ,  A61F2230/005 ,  A61F2250/006

    Abstract: A quick-connect heart valve prosthesis that can be quickly and easily implanted is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable coupling stent, thereby enabling attachment to the annulus without sutures. A small number of guide sutures may be provided for aortic valve orientation. The prosthetic valve may be a commercially available valve with a sewing ring with the coupling stent attached thereto. The coupling stent may expand from a conical deployment shape to a conical expanded shape, and may include web-like struts connected between axially-extending posts. A system and method for deployment includes a hollow two-piece handle through which a balloon catheter passes. A valve holder is stored with the heart valve and the handle easily attaches thereto to improve valve preparation steps.

    Abstract translation: 提供了可以快速且容易地植入的快速连接的心脏瓣膜假体。 心脏瓣膜包括基本上不可膨胀的不可压缩的人造瓣膜和塑性可扩张的联接支架，从而使得能够在不缝合的情况下连接到环形空间。 可以提供少量的导向缝线用于主动脉瓣取向。 假体瓣膜可以是具有连接有联接支架的缝合环的市售阀。 联接支架可以从锥形展开形状扩展到圆锥形膨胀形状，并且可以包括连接在轴向延伸柱之间的腹板状支柱。 用于展开的系统和方法包括气球导管通过的中空两件式手柄。 与心脏瓣膜一起存储阀保持器，并且手柄容易地附接到其上以改善阀门准备步骤。

    Heart Valve Sealing Devices
    15.
    发明申请
    Heart Valve Sealing Devices 有权
    心脏瓣膜密封装置

    公开(公告)号：US20140067052A1

    公开(公告)日：2014-03-06

    申请号：US14019332

    申请日：2013-09-05

    Applicant: Edwards Lifesciences Corporation

    Inventor： Mark Chau ,  Travis Oba ,  Sergio Delgado ,  Robert C. Taft

    IPC: A61F2/24

    CPC classification number: A61F2/2436 ,  A61F2/2412 ,  A61F2/243 ,  A61F2/2433 ,  A61F2/2442 ,  A61F2/2445 ,  A61F2/2454 ,  A61F2/2457 ,  A61F2/246 ,  A61F2/2463 ,  A61F2/2466 ,  A61F2230/0069 ,  A61F2250/0003

    Abstract: This disclosure pertains generally to prosthetic devices and related methods for helping to seal native heart valves and prevent or reduce regurgitation therethrough, as well as devices and related methods for implanting such prosthetic devices. In some cases, a spacer having a single anchor can be implanted within a native heart valve. In some cases, a spacer having dual anchors can be implanted within a native heart valve. In some cases, devices can be used to extend the effective length of a native heart valve leaflet.

    Abstract translation: 本公开总体上涉及用于帮助密封天然心脏瓣膜并防止或减少反流的假体装置和相关方法，以及用于植入这种假体装置的装置和相关方法。 在一些情况下，具有单个锚的间隔物可以植入天然心脏瓣膜内。 在一些情况下，具有双重锚的间隔物可以植入天然心脏瓣膜内。 在某些情况下，可以使用装置来延长天然心脏瓣膜小叶的有效长度。

    Method for Implanting a Prosthetic Mitral Valve
    16.
    发明申请
    Method for Implanting a Prosthetic Mitral Valve 有权
    植入假体二尖瓣的方法

    公开(公告)号：US20140012373A1

    公开(公告)日：2014-01-09

    申请号：US14025701

    申请日：2013-09-12

    Applicant: Edwards Lifesciences Corporation

    Inventor： Mark Chau ,  Marlowe E. Patterson ,  Seung-Beom Yi ,  Stephen C. Geist ,  Travis Oba ,  David L. Hauser

    IPC: A61F2/24

    CPC classification number: A61F2/2412 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/2445 ,  A61F2/246 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2230/0069 ,  A61F2250/006 ,  A61F2250/0063

    Abstract: Embodiments of a method for implanting a prosthetic valve at the native mitral valve region of the heart, the prosthetic valve including a main body that is radially compressible to a radially compressed state and self-expandable from the compressed state to a radially expanded state. The prosthetic apparatus also comprises at least one ventricular anchor coupled to the main body and disposed outside of the main body with a leaflet-receiving space between the anchor and an outer surface of the main body to receive a native valve leaflet. Apparatus for delivering and implanting the prosthetic valve are also described.

    Abstract translation: 用于在心脏的天然二尖瓣区域植入人工瓣膜的方法的实施例，所述假体瓣膜包括可径向压缩到径向压缩状态并且可从压缩状态自发展到径向扩张状态的主体。 假体装置还包括耦合到主体并且设置在主体外部的至少一个心室锚固体，其具有在锚固体和主体的外表面之间的小叶容纳空间，以接收天然瓣膜小叶。 还描述了用于输送和植入人造瓣膜的装置。

    Systems for quickly delivering a prosthetic heart valve
    18.
    发明授权
    Systems for quickly delivering a prosthetic heart valve 有权
    用于快速输送假体心脏瓣膜的系统

    公开(公告)号：US09561100B2

    公开(公告)日：2017-02-07

    申请号：US14684267

    申请日：2015-04-10

    Applicant: Edwards Lifesciences Corporation

    Inventor： Rafael Pintor ,  Mark Chau ,  Travis Oba ,  August R. Yambao ,  Louis A. Campbell ,  Tammy Huntley ,  Qinggang Zeng ,  Carey L. Cristea ,  Faisal Kalam

    IPC: A61F2/24

    CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2/243 ,  A61F2/2433 ,  A61F2220/0016 ,  A61F2220/0025 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2220/0083 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/0069 ,  A61F2230/0078 ,  A61F2250/006

    Abstract: A heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve has a base stent that is deployed at a treatment site, and a valve component configured to quickly connect to the base stent. The base stent may take the form of a self- or balloon-expandable stent that expands outward against the native valve with or without leaflet excision. The valve component has a non-expandable prosthetic valve and a self- or balloon-expandable coupling stent for attachment to the base stent, thereby fixing the position of the valve component relative to the base stent. The prosthetic valve may be a commercially available to valve with a sewing ring and the coupling stent attaches to the sewing ring. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment. A catheter-based system and method for deployment is provided.

    Abstract translation: 提供了可以在手术过程中快速且容易地植入的心脏瓣膜假体。 假体瓣膜具有部署在治疗部位的基部支架和构造成快速连接到基部支架的阀部件。 基底支架可以采取自体或球囊扩张的支架的形式，其在具有或不具有小叶切除的情况下相对于天然瓣膜向外扩张。 阀部件具有不可扩张的假体瓣膜和用于附接到基底支架的自支撑或球囊扩张的联接支架，由此固定阀部件相对于基底支架的位置。 人造瓣膜可以是市售的，具有缝合环的阀门，并且联接支架附接到缝合环。 该系统特别适用于在常规开心手术环境中快速部署心脏瓣膜。 提供了基于导管的系统和部署方法。

    METHODS OF IMPLANTING A HEART VALVE AT AN AORTIC ANNULUS
    20.
    发明申请
    METHODS OF IMPLANTING A HEART VALVE AT AN AORTIC ANNULUS 有权
    在动静脉注射心脏瓣膜的方法

    公开(公告)号：US20160128829A1

    公开(公告)日：2016-05-12

    申请号：US15001114

    申请日：2016-01-19

    Applicant: Edwards Lifesciences Corporation

    Inventor： Travis Oba ,  Rafael Pintor ,  Louis A. Campbell

    IPC: A61F2/24

    CPC classification number: A61F2/243 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/2433 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2220/0083 ,  A61F2230/0054 ,  A61F2230/008 ,  A61F2250/0063 ,  A61F2250/0097 ,  A61F2250/0098

    Abstract: An exemplary two-stage prosthetic heart valve system has a radially expandable base stent implanted within a native valve annulus. The two-stage heart valve system also has a valve component that is delivered to and mounted within the base stent in a separate or sequential operation after the base stent has been anchored within the annulus. The valve component in certain embodiments comprises a hybrid valve component that includes a conventional, non-expandable surgical valve that is modified to include an expandable coupling stent that can be expanded to engage the inner surface of the base stent, thereby anchoring the valve component to the base stent. In its expanded configuration, the outflow end portion base stent has tri-lobular shape that closely conforms to the shape of the aortic root and a support ring of the prosthetic valve that is mounted within the base stent.

    Abstract translation: 示例性的两级假体心脏瓣膜系统具有植入在天然瓣膜环内的径向可扩展的基底支架。 两级心脏瓣膜系统还具有阀组件，其在基础支架已经被锚定在环空中之后以单独的或顺序的操作被输送并安装在基础支架内。 在某些实施方案中，阀部件包括混合阀部件，其包括常规的不可扩张的外科手术阀，其被修改为包括可膨胀以可接合基部支架的内表面的可扩张联接支架，从而将阀部件固定到 基础支架。 在其膨胀构造中，流出端部基部支架具有三小叶形状，其紧密地与主动脉根部的形状以及安装在基底支架内的人工瓣膜的支撑环相吻合。

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