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公开(公告)号:US12048623B2
公开(公告)日:2024-07-30
申请号:US17492408
申请日:2021-10-01
Applicant: Edwards Lifesciences Corporation
Inventor: Nikolay Gurovich , Michael Bukin , Alexey Tsypenyuk , Elena Sherman , Dikla Kersh , Boaz Manash , Liron Tayeb , Ziv Yohanan , Alexander Barash , Yair A. Neumann , Tomer Saar
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2220/0033 , A61F2220/0075 , A61F2220/0091 , A61F2230/0069
Abstract: A prosthetic valve has an annular frame including a plurality of strut members that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration. A leaflet structure is situated at least partially within the frame. The leaflet structure includes a plurality of leaflets, each leaflet having opposing commissure tab portions on opposite sides of the leaflet. Each commissure tab portion is paired with an adjacent commissure tab portion of an adjacent leaflet to form a commissure. The commissure tab portions of each leaflet are folded to form a plurality of layers positioned on the inside of the frame. A reinforcement member is positioned between the layers of each commissure tab portion.
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公开(公告)号:US11648113B2
公开(公告)日:2023-05-16
申请号:US17063428
申请日:2020-10-05
Applicant: Edwards Lifesciences Corporation
Inventor: Oren Cohen , Ofir Witzman , Yair A. Neumann
CPC classification number: A61F2/243 , A61F2/2418 , A61F2/2439 , A61F2/9517 , A61F2002/9511
Abstract: A prosthetic valve delivery apparatus can comprise a handle, a gearbox, an input torque shaft and a plurality of output torque shafts. The input torque shaft can extend distally from the handle and can have a distal end portion operatively connected to the gearbox. The output torque shafts can be operatively connected to and extend distally from the gearbox. Rotation of the input torque shaft can cause rotation of the output torque shafts via the gear box.
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公开(公告)号:US20220401215A1
公开(公告)日:2022-12-22
申请号:US17894051
申请日:2022-08-23
Applicant: Edwards Lifesciences Corporation
Inventor: Anatoly Dvorsky , Tamir S. Levi , Yair A. Neumann , Noa Axelrod Manela , Eitan Atias , Oren Cohen , Elazar Levi Schwarcz , Ofir Witzman , Noam Miller , Boaz Manash , Danny M. Garmahi
Abstract: An implantable prosthetic device can include a frame that is radially expandable and compressible between a radially compressed configuration and a radially expanded configuration. The frame can have a first set of a plurality of struts extending in a first direction, and a second set of a plurality of struts extending in a second direction, and each strut of the first set of struts can be pivotably connected to at least one strut of the second set of struts. Each strut can be curved helically with respect to a first, longitudinal axis of the frame, and each strut can be curved with respect to a second axis that is perpendicular to the first, longitudinal axis of the frame.
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公开(公告)号:US20220023038A1
公开(公告)日:2022-01-27
申请号:US17492408
申请日:2021-10-01
Applicant: Edwards Lifesciences Corporation
Inventor: Nikolay Gurovich , Michael Bukin , Alexey Tsypenyuk , Elena Sherman , Dikla Kersh , Boaz Manash , Liron Tayeb , Ziv Yohanan , Alexander Barash , Yair A. Neumann , Tomer Saar
IPC: A61F2/24
Abstract: A prosthetic valve has an annular frame including a plurality of strut members that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration. A leaflet structure is situated at least partially within the frame. The leaflet structure includes a plurality of leaflets, each leaflet having opposing commissure tab portions on opposite sides of the leaflet. Each commissure tab portion is paired with an adjacent commissure tab portion of an adjacent leaflet to form a commissure. The commissure tab portions of each leaflet are folded to form a plurality of layers positioned on the inside of the frame. A reinforcement member is positioned between the layers of each commissure tab portion.
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公开(公告)号:US20210307904A1
公开(公告)日:2021-10-07
申请号:US17353702
申请日:2021-06-21
Applicant: Edwards Lifesciences Corporation
Inventor: Elazar Levi Schwarcz , Oren Cohen , Ofir Witzman , Yair A. Neumann , Noam Miller , Ziv Yohanan
IPC: A61F2/24
Abstract: Embodiments of a prosthetic valve delivery apparatus are disclosed. The delivery apparatus includes a first portion configured to maintain a fixed spatial relationship relative to a first end of the prosthetic valve and a second portion configured to maintain a fixed spatial relationship relative to a second end of the prosthetic valve during radial expansion of the prosthetic valve. The first portion includes one or more reference radiopaque markers and the second portion includes an indicator radiopaque marker. A position of the indicator radiopaque marker relative to the one or more reference radiopaque markers measures an axial distance between the first and second ends of the prosthetic valve indicative of a corresponding diameter of the prosthetic valve as it is radially expanded from a radially compressed state to a radially expanded state.
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公开(公告)号:US10806573B2
公开(公告)日:2020-10-20
申请号:US16105353
申请日:2018-08-20
Applicant: Edwards Lifesciences Corporation
Inventor: Oren Cohen , Ofir Witzman , Yair A. Neumann
Abstract: A prosthetic valve delivery apparatus can comprise a handle, a gearbox, an input torque shaft and a plurality of output torque shafts. The input torque shaft can extend distally from the handle and can have a distal end portion operatively connected to the gearbox. The output torque shafts can be operatively connected to and extend distally from the gearbox. Rotation of the input torque shaft can cause rotation of the output torque shafts via the gear box.
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公开(公告)号:US20200297482A1
公开(公告)日:2020-09-24
申请号:US16813637
申请日:2020-03-09
Applicant: Edwards Lifesciences Corporation
Inventor: David Maimon , Boaz Manash , Eyal Leiba , Ziv Yohanan , Yair A. Neumann , Anatoly Dvorsky , Jonathan Bar-Or , Oren Cohen , Ofir Witzman , Liron Tayeb , Elazar Levi Schwarcz , Noam Miller , Tomer Saar
IPC: A61F2/24
Abstract: An assembly can comprise a radially expandable and compressible annular frame, at least one linear actuator assembly coupled to the frame and at least one locking mechanism coupled to the frame. The linear actuator can be configured to apply a distally directed force and/or a proximally directed force to the frame to radially expand or compress the frame. The locking mechanism can comprise a first sleeve member connected to the frame at a first location, a second sleeve member having internal threads and being connected to the frame at a second location, and a first screw configured to engage the internal threads of the second sleeve member to retain the frame in a radially expanded state.
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公开(公告)号:US20190307589A1
公开(公告)日:2019-10-10
申请号:US16378417
申请日:2019-04-08
Applicant: Edwards Lifesciences Corporation
Inventor: Eran Goldberg , Noa Axelrod , Yair A. Neumann , Boaz Manash , David Maimon , Eyal Leiba , Ralph Schneider , Liron Tayeb
Abstract: An expandable sheath is disclosed herein, which has a first polymeric layer and a braided layer positioned radially outward of the first polymeric layer. The braided layer includes a plurality of filaments braided together. The expandable sheaths further include a resilient elastic layer positioned radially outward of the braided layer. The elastic layer is configured to apply radial force to the braided layer and the first polymeric layer. The expandable sheath further includes a second polymeric layer positioned radially outward of the elastic layer and bonded to the first polymeric layer such that the braided layer and the elastic layer are encapsulated between the first and second polymeric layers. Methods of making and using the devices disclosed herein are also disclosed, as are crimping devices that may be used in methods of making the devices disclosed herein.
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公开(公告)号:US20250082832A1
公开(公告)日:2025-03-13
申请号:US18957242
申请日:2024-11-22
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor: Hans Christof , Leon Wenning , Kenneth M. Martin , Inga Schellenberg , Hardy Baumbach , Thomas Friedrich , Mario Heintze , Hien T. Nguyen , Daniel James Murray , Michael G. Valdez , Yair A. Neumann , Anne Bernadette Aragon Alcasid , Amir Davidesko , Steven Park , Sofia Rozenberg , Linda Thai , Cristobal R. Hernandez , Omar Fawzi Azanki
IPC: A61M1/36
Abstract: An insertion catheter for a circulatory support catheter having a circulatory support device carried by an elongate flexible catheter shaft. The insertion catheter comprises a tubular body with a distal portion configured to axially movably receive the circulatory support device. A diameter of the distal portion is greater than a diameter of a mid portion of the tubular body. The insertion catheter may be inserted into an introducer sheath for delivery of the MCS device. A distal end of the insertion catheter may be located distally of a distal end of the introducer sheath and distally of the arterial bifurcation. The distal portion of the insertion catheter containing the MCS device may be located distally of the bifurcation, with a distal end of the MCS device slightly offset from the distal end of the tubular body.
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公开(公告)号:US20240424286A1
公开(公告)日:2024-12-26
申请号:US18823586
申请日:2024-09-03
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor: Hien T. Nguyen , Daniel James Murray , Michael G. Valdez , Yair A. Neumann , Anne Bernadette Aragon Alcasid , Amir Davidesko , Steven Park , Sofia Rozenberg
IPC: A61M60/865 , A61M25/00 , A61M60/187 , A61M60/289 , A61M60/465
Abstract: A medical device delivery system can comprise a delivery catheter and an in-line sheath, the delivery catheter being preloaded within the in-line sheath. The delivery catheter can comprise a catheter hub and a catheter shaft. The catheter shaft can comprise a proximal portion extending distally from the hub and slidably receiving a proximal narrow portion of a medical device, and a distal portion slidably receiving a distal wide portion of a medical device. The in-line sheath can comprise a sheath hub and a sheath shaft. The sheath shaft can comprise a proximal portion extending distally from the sheath hub and slidably receiving at least a portion of the proximal portion of the catheter shaft, and an expandable distal portion slidably receiving the distal portion of the catheter shaft.
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