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公开(公告)号:US20190000615A1
公开(公告)日:2019-01-03
申请号:US16034794
申请日:2018-07-13
发明人: Liron Tayeb , Eran Goldberg , David Maimon , Adi Carmi , Arie Tylis , Ofir Witzman , Ralph Schneider , Mohammad Jafari , Hengchu Cao , Eason Michael Abbott , Dustin P. Armer , Michael D. Franklin , Tomer Saar , Anatoly Dvorsky , John J. Desrosiers , Daniel James Murray , Michael G. Valdez , Assaf Bash , Amir Blumenfeld , Noa Axelrod , Eitan Atias
IPC分类号: A61F2/24
摘要: Docking stations for transcatheter valves are described. The docking stations can include an expandable frame, at least one sealing portion, and a valve seat. The expandable frame can be configured to conform to an interior shape of a portion of the circulatory system when expanded inside the circulatory system. The sealing portion can be configured to contact an interior surface of the circulatory system to create a seal. The valve seat can be connected to the expandable frame and can be configured to support an expandable transcatheter valve. The docking stations are adaptable to different anatomies/locations to allow implantation of a transcatheter valve in a variety of anatomies/locations.
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公开(公告)号:US20170135818A1
公开(公告)日:2017-05-18
申请号:US15353666
申请日:2016-11-16
发明人: Noa Axelrod , Oren Wintner , Eran Goldberg , Dikla Kersh , Danny Garnahi , Dan Rottenberg , Boaz Manash
摘要: Ultrasound probe systems and methods for using an ultrasound probe to assist during treatment of conditions of the human heart are provided. The method may comprise loading a medical instrument into a guide fastened to the ultrasound probe. The ultrasound probe may be inserted into a patient by way of an incision. The distal end of the ultrasound probe may be navigated to a location adjacent to an exterior surface of the heart. A treatment site may be identified on the exterior surface of the heart based on images obtained from an ultrasound transducer disposed within a distal end of the ultrasound probe. The medical instrument may be advanced within the guide to the treatment site and the medical instrument used for treatment. After treatment, the medical instrument may be withdrawn from the treatment site.
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公开(公告)号:US20200000579A1
公开(公告)日:2020-01-02
申请号:US16442165
申请日:2019-06-14
发明人: Boaz Manash , Khen Perlmutter , Adi Carmi , Noa Axelrod , Nikolay Gurovich
IPC分类号: A61F2/24
摘要: A prosthetic heart valve is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration. The heart valve includes an annular inner frame formed with a plurality of angled first strut members, the inner frame being configured to foreshorten from a first length corresponding to the collapsed configuration to a second length corresponding to the expanded configuration. A leaflet structure is situated at least partially within the inner frame. An outer frame is disposed radially outward of the inner frame and coupled to the inner frame. The outer frame is configured to collapse with the inner frame and radially expand with the inner frame, and includes a plurality of second strut members. Portions of the second strut members are configured to bend radially outwardly into a curved shape as the inner frame and the outer frame move from the collapsed configuration to the expanded configuration.
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公开(公告)号:US20180177594A1
公开(公告)日:2018-06-28
申请号:US15902956
申请日:2018-02-22
发明人: Darshin S. Patel , Boaz Manash , Khen Perlmutter , Eyal Leiba , Yoav Rozen , Dinesh L. Sirimanne , Tri D. Tran , Jocelyn Chau , Noa Axelrod , Zohar Kiblitski
IPC分类号: A61F2/24
摘要: Docking devices for docking a prosthetic valve at a native valve of a heart can include a coiled docking anchor and a retrieval suture. The docking device and retrieval suture can be configured for improved retention and retrieval of the docking device after deployment. The docking devices can have an end portion with a central axis. The retrieval suture can be connected to the end portion such that a line of force applied by applying tension to the retrieval suture is substantially aligned with the central axis.
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公开(公告)号:US11291540B2
公开(公告)日:2022-04-05
申请号:US16034794
申请日:2018-07-13
发明人: Liron Tayeb , Eran Goldberg , David Maimon , Adi Carmi , Arie Tylis , Ofir Witzman , Ralph Schneider , Mohammad Jafari , Hengchu Cao , Eason Michael Abbott , Dustin P. Armer , Michael D. Franklin , Tomer Saar , Anatoly Dvorsky , John J. Desrosiers , Daniel James Murray , Michael G. Valdez , Assaf Bash , Amir Blumenfeld , Noa Axelrod , Eitan Atias
摘要: Docking stations for transcatheter valves are described. The docking stations can include an expandable frame, at least one sealing portion, and a valve seat. The expandable frame can be configured to conform to an interior shape of a portion of the circulatory system when expanded inside the circulatory system. The sealing portion can be configured to contact an interior surface of the circulatory system to create a seal. The valve seat can be connected to the expandable frame and can be configured to support an expandable transcatheter valve. The docking stations are adaptable to different anatomies/locations to allow implantation of a transcatheter valve in a variety of anatomies/locations.
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公开(公告)号:US20200060811A1
公开(公告)日:2020-02-27
申请号:US16673660
申请日:2019-11-04
发明人: Darshin S. Patel , Boaz Manash , Khen Perlmutter , Yoav Rozen , Dinesh L. Sirimanne , Zohar Kiblitski , Noa Axelrod
IPC分类号: A61F2/24
摘要: Anchoring or docking devices configured to be positioned at a native valve of a human heart and to provide structural support for docking a prosthetic valve therein. The docking devices can have coiled structures that define an inner space in which the prosthetic valve can be held. The docking devices can have enlarged end regions with circular or non-circular shapes, for example, to facilitate implantation of the docking device or to better hold the docking device in position once deployed. The docking devices can be laser-cut tubes with locking wires to assist in better maintaining a shape of the docking device. The docking devices can include various features to promote friction, such as frictional cover layers. Such docking devices can have ends configured to more securely attach the cover layers to cores of the docking devices.
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公开(公告)号:US10463479B2
公开(公告)日:2019-11-05
申请号:US15682287
申请日:2017-08-21
发明人: Boaz Manash , Darshin S. Patel , Khen Perlmutter , Yoav Rozen , Dinesh L. Sirimanne , Zohar Kiblitski , Noa Axelrod
IPC分类号: A61F2/24 , A61B17/00 , A61B17/064
摘要: Anchoring or docking devices configured to be positioned at a native valve of a human heart and to provide structural support for docking a prosthetic valve therein. The docking devices can have coiled structures that define an inner space in which the prosthetic valve can be held. The docking devices can have enlarged end regions with circular or non-circular shapes, for example, to facilitate implantation of the docking device or to better hold the docking device in position once deployed. The docking devices can be laser-cut tubes with locking wires to assist in better maintaining a shape of the docking device. The docking devices can include various features to promote friction, such as frictional cover layers. Such docking devices can have ends configured to more securely attach the cover layers to cores of the docking devices.
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8.
公开(公告)号:US12029650B2
公开(公告)日:2024-07-09
申请号:US16534534
申请日:2019-08-07
发明人: Noa Axelrod , Boaz Manash , David Maimon
CPC分类号: A61F2/2487 , A61F2220/0008 , A61F2220/0075 , A61F2230/0006 , A61F2230/0039 , A61F2230/0091 , A61F2250/0065
摘要: A cardiac device comprises a first anchoring element configured to be attached to a first side of a tissue wall, a second anchoring element configured to be attached to a second side of the tissue wall, and a cinching device. The cinching device is configured to attach to the first anchoring element and the second anchoring element and apply force to the first anchoring element to move the first anchoring element towards the second anchoring element and at least partially compress the tissue wall.
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公开(公告)号:US11083571B2
公开(公告)日:2021-08-10
申请号:US16442165
申请日:2019-06-14
发明人: Boaz Manash , Khen Perlmutter , Adi Carmi , Noa Axelrod , Nikolay Gurovich
IPC分类号: A61F2/24
摘要: A prosthetic heart valve is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration. The heart valve includes an annular inner frame formed with a plurality of angled first strut members, the inner frame being configured to foreshorten from a first length corresponding to the collapsed configuration to a second length corresponding to the expanded configuration. A leaflet structure is situated at least partially within the inner frame. An outer frame is disposed radially outward of the inner frame and coupled to the inner frame. The outer frame is configured to collapse with the inner frame and radially expand with the inner frame, and includes a plurality of second strut members. Portions of the second strut members are configured to bend radially outwardly into a curved shape as the inner frame and the outer frame move from the collapsed configuration to the expanded configuration.
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公开(公告)号:US20190307589A1
公开(公告)日:2019-10-10
申请号:US16378417
申请日:2019-04-08
发明人: Eran Goldberg , Noa Axelrod , Yair A. Neumann , Boaz Manash , David Maimon , Eyal Leiba , Ralph Schneider , Liron Tayeb
摘要: An expandable sheath is disclosed herein, which has a first polymeric layer and a braided layer positioned radially outward of the first polymeric layer. The braided layer includes a plurality of filaments braided together. The expandable sheaths further include a resilient elastic layer positioned radially outward of the braided layer. The elastic layer is configured to apply radial force to the braided layer and the first polymeric layer. The expandable sheath further includes a second polymeric layer positioned radially outward of the elastic layer and bonded to the first polymeric layer such that the braided layer and the elastic layer are encapsulated between the first and second polymeric layers. Methods of making and using the devices disclosed herein are also disclosed, as are crimping devices that may be used in methods of making the devices disclosed herein.
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