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公开(公告)号：US20100063082A1
公开(公告)日：2010-03-11
申请号：US12374799
申请日：2007-07-12
IPC分类号： A61K31/4375 , C07D471/22 , A61P35/00
CPC分类号： Y02P20/55
摘要： Novel camptothecin derivatives having antitumor activity, the processes for the preparation thereof, the use thereof as antitumor drugs and pharmaceutical compositions containing them.
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公开(公告)号：US06768012B2
公开(公告)日：2004-07-27
申请号：US10433601
申请日：2003-06-05
IPC分类号： C07D30514
CPC分类号： C07D305/14
摘要： A process for the preparation of paclitaxel starting from 10-deacetylbaccatine III.
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13.发明授权公开(公告)号：US07153884B2
公开(公告)日：2006-12-26
申请号：US10485982
申请日：2002-07-23
IPC分类号： A61K31/337 , A61K31/381 , C07D305/14 , C07D407/10 , C07D409/10
CPC分类号： C07D407/12 , C07D305/14
摘要： Taxane derivatives of formula (I) in which: R is trifluoromethyl, phenyl, 2-furyl, 2-thienyl; R1 is t-butoxycarbonyl or benzoyl; R2 is hydroxy; R3 is hydrogen or, together with R2, it forms the residue of a cyclic carbonate of formula: II with the proviso that when R3 is hydrogen, R is different from phenyl. Compounds of formula (I) have antitumor activity
摘要翻译： 式（I）的紫杉烷衍生物，其中：R是三氟甲基，苯基，2-呋喃基，2-噻吩基; R 1是叔丁氧基羰基或苯甲酰基; R 2是羟基; R 3是氢或与R 2一起形成式II的环状碳酸酯的残基，条件是当R 3是氢时，R不同 苯基。 式（I）化合物具有抗肿瘤活性
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公开(公告)号：US09247750B2
公开(公告)日：2016-02-02
申请号：US12678695
申请日：2008-09-15
申请人： Valerio Borzatta , Greta Varchi , Elisa Capparella , Alberto Guerrini , Arturo Battaglia , Federico Trefiletti
发明人： Valerio Borzatta , Greta Varchi , Elisa Capparella , Alberto Guerrini , Arturo Battaglia , Federico Trefiletti
IPC分类号： A01N53/00 , C07C67/343 , C07C69/743
CPC分类号： A01N53/00 , C07C67/343 , C07C69/743 , C07C2601/02
摘要： Described are new insecticide compounds that are derived from 2,2-dimethyl-3-(2-methylpropenyl)cyclopropanecarboxylic acid, also known as chrysanthemic acid, insecticidal compositions that contain the compounds, methods of synthesizing the compounds and methods of eliminating harmful insects from a substrate including bringing the substrate into contact with an effective amount of one or more such compounds.
摘要翻译： 描述了衍生自2,2-二甲基-3-（2-甲基丙烯基）环丙烷羧酸的新型杀虫剂化合物，也被称为菊酸，含有化合物的杀虫组合物，合成化合物的方法和消除有害昆虫的方法 底物，包括使基质与有效量的一种或多种这样的化合物接触。
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公开(公告)号：US20100210721A1
公开(公告)日：2010-08-19
申请号：US12678695
申请日：2008-09-15
申请人： Valerio Borzatta , Greta Varchi , Elisa Capparella , Alberto Guerrini , Arturo Battaglia , Federico Trefiletti
发明人： Valerio Borzatta , Greta Varchi , Elisa Capparella , Alberto Guerrini , Arturo Battaglia , Federico Trefiletti
IPC分类号： A01N53/06 , C07C69/743 , A01P7/04 , C07C67/08
CPC分类号： A01N53/00 , C07C67/343 , C07C69/743 , C07C2601/02
摘要： Described are new insecticide compounds that are derived from 2,2-dimethyl-3-(2-methylpropenyl)cyclopropanecarboxylic acid, also known as chrysanthemic acid, insecticidal compositions that contain the compounds, methods of synthesizing the compounds and methods of eliminating harmful insects from a substrate including bringing the substrate into contact with an effective amount of one or more such compounds.
摘要翻译： 描述了衍生自2,2-二甲基-3-（2-甲基丙烯基）环丙烷羧酸的新型杀虫剂化合物，也被称为菊酸，含有化合物的杀虫组合物，合成化合物的方法和消除有害昆虫的方法 底物，包括使基质与有效量的一种或多种这样的化合物接触。
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