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公开(公告)号:US09067979B2
公开(公告)日:2015-06-30
申请号:US14275174
申请日:2014-05-12
Applicant: Genentech, Inc.
Inventor: Min Xu , Mercedesz Balazs , Ning Chai , Nancy Chiang , Henry Chiu , Zhonghua Lin , Patrick Lupardus , Gerald R. Nakamura , Hyunjoo Park , Lee Swern
IPC: C07K16/10 , A61K31/215 , A61K39/42 , A61K39/00
CPC classification number: C07K16/1018 , A61K31/215 , A61K31/235 , A61K31/24 , A61K39/42 , A61K2039/505 , A61K2039/507 , A61K2039/545 , C07K2317/21 , C07K2317/33 , C07K2317/56 , C07K2317/76 , C07K2317/94 , A61K2300/00
Abstract: The present invention provides anti-hemagglutinin antibodies, compositions comprising anti-hemagglutinin antibodies, and methods of using the same.
Abstract translation: 本发明提供抗血凝素抗体,包含抗血凝素抗体的组合物及其使用方法。
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12.METHODS OF USING ANTI-PD-L1 ANTIBODIES AND THEIR USE TO ENHANCE T-CELL FUNCTION TO TREAT TUMOR IMMUNITY 审中-公开
Title translation: 使用抗PD-L1抗体及其用于增强T细胞功能以治疗肿瘤免疫的方法公开(公告)号:US20140065135A1
公开(公告)日:2014-03-06
申请号:US13954796
申请日:2013-07-30
Applicant: Genentech, Inc.
Inventor: Bryan Irving , Henry Chiu , Heather Maecker , Sanjeev Mariathasan , Sophie M. Lehar , Yan Wu , Jeanne Cheung
IPC: C07K16/28 , A61K45/06 , A61K39/395 , A61K39/00
CPC classification number: C07K16/2827 , A61K31/7068 , A61K39/00 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/1063 , C07K16/22 , C07K16/28 , C07K16/30 , C07K16/3046 , C07K2317/14 , C07K2317/24 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/71 , C07K2317/73 , C07K2317/74 , C07K2317/76 , C07K2317/92 , Y02A50/41 , Y02A50/412 , Y02A50/423 , Y02A50/489 , Y02A50/492 , A61K2300/00
Abstract: The present application relates to methods of using anti-PD-L1 antibodies to enhance T-cell function to upregulate cell-mediated immune responses and for the treatment of T cell dysfunctional disorders, including infection (e.g., acute and chronic) and tumor immunity.
Abstract translation: 本申请涉及使用抗PD-L1抗体来增强T细胞功能以上调细胞介导的免疫应答和治疗T细胞功能障碍(包括感染(例如急性和慢性))和肿瘤免疫的方法。
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