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公开(公告)号:US10508151B2
公开(公告)日:2019-12-17
申请号:US15525832
申请日:2015-11-18
Applicant: Genentech, Inc.
Inventor: Yin Zhang , Joy Yu Zuchero , Jasvinder Atwal , Jessica Couch , Mark S Dennis , James A Ernst , Ryan J Watts , Gregory A Lazar
IPC: C07K16/28 , C07K16/40 , A61K39/395 , A61K39/00
Abstract: The present invention relates to anti-transferrin receptor antibodies and methods of their use.
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公开(公告)号:US20180134797A1
公开(公告)日:2018-05-17
申请号:US15525832
申请日:2015-11-18
Applicant: Genentech, Inc.
Inventor: Yin Zhang , Joy Yu Zuchero , Jasvinder Atwal , Jessica Couch , Mark S Dennis , James A Ernst , Ryan J Watts , Gregory A Lazar
IPC: C07K16/28 , C07K16/40 , A61K39/395
CPC classification number: C07K16/2881 , A61K39/39558 , A61K2039/505 , C07K16/283 , C07K16/40 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/41 , C07K2317/52 , C07K2317/524 , C07K2317/526 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/71 , C07K2317/72 , C07K2317/732 , C07K2317/90 , C07K2317/92 , C07K2317/94
Abstract: The present invention relates to anti-trans-ferrin receptor antibodies and methods of their use.
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公开(公告)号:US20180000964A1
公开(公告)日:2018-01-04
申请号:US15618467
申请日:2017-06-09
Applicant: Genentech, Inc.
Inventor: Christine Tan , Ryan J. Watts , Joy Yu Zuchero , Xiaocheng Chen , Mark S. Dennis
CPC classification number: A61K47/6849 , A61K2039/505 , A61K2039/54 , A61K2039/545 , C07K16/18 , C07K16/26 , C07K16/2803 , C07K16/2896 , C07K16/40 , C07K2317/31 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/92 , C12Y304/23046
Abstract: The present invention relates to antibodies that bind to receptors expressed on the blood brain barrier and methods of using the same.
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14.METHODS FOR IMPROVING SAFETY OF BLOOD-BRAIN BARRIER TRANSPORT 审中-公开
Title translation: 改善血液屏障运输安全的方法公开(公告)号:US20150353639A1
公开(公告)日:2015-12-10
申请号:US14761895
申请日:2013-05-20
Applicant: Genentech, Inc.
Inventor: Ryan Jefferson Watts , Joy Yu Zuchero , Jessica Couch , Mark Dennis
CPC classification number: A61K39/3955 , A61K35/18 , A61K39/39583 , A61K47/6849 , A61K47/6879 , A61K2039/505 , A61K2039/545 , C07K16/2881 , C07K16/40 , C07K16/44 , C07K16/468 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/41 , C07K2317/52 , C07K2317/71 , C07K2317/90 , C07K2317/92 , C07K2317/94 , C07K2319/30
Abstract: The present disclosure relates to compositions and methods for improving the safety of blood-brain barrier receptor-mediated blood-brain barrier transport.
Abstract translation: 本公开涉及用于改善血脑屏障受体介导的血脑屏障转运的安全性的组合物和方法。
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