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公开(公告)号：US20230041134A1
公开(公告)日：2023-02-09
申请号：US17720717
申请日：2022-04-14
申请人： Genentech, Inc.
发明人： Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC分类号： C07K16/32 , A61K47/68 , A61K39/395 , C07K16/28 , G01N33/574 , A61K31/5517 , A61K31/675 , A61K31/704 , A61K49/00 , C07K16/30
摘要： The invention provides anti-HER2 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号：US10752703B2
公开(公告)日：2020-08-25
申请号：US16544421
申请日：2019-08-19
申请人： Genentech, Inc.
发明人： Xiaocheng Chen , Mark Dennis , Janet Jackman , James T. Koerber , Mason Lu , Henry R. Maun , Kathila Rajapaksa , Saroja Ramanujan , Tracy Staton , Lawren Wu , Tangsheng Yi
IPC分类号： C07K16/40 , A61K39/395 , A61K39/00 , A61K47/18 , A61K47/22 , A61K47/26 , A61K47/10 , A61K45/06 , C07K16/24
摘要： The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.
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公开(公告)号：US20190177429A1
公开(公告)日：2019-06-13
申请号：US16170819
申请日：2018-10-25
申请人： Genentech, Inc.
发明人： Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC分类号： C07K16/32 , G01N33/574 , A61K49/00 , A61K39/395 , A61K31/704 , A61K31/675 , A61K31/5517 , C07K16/30 , A61K47/68 , C07K16/28
摘要： The invention provides anti-HER2 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号：US20200255539A1
公开(公告)日：2020-08-13
申请号：US16721525
申请日：2019-12-19
申请人： Genentech, Inc.
发明人： Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC分类号： C07K16/32 , G01N33/574 , C07K16/30 , A61K49/00 , A61K31/704 , A61K31/675 , A61K31/5517 , C07K16/28 , A61K39/395 , A61K47/68
摘要： The invention provides anti-HER2 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号：US20200085840A1
公开(公告)日：2020-03-19
申请号：US16391738
申请日：2019-04-23
申请人： Genentech, Inc.
发明人： Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC分类号： A61K31/5517 , A61K47/68 , A61K39/395 , C07K16/00 , C07K16/32
摘要： The invention provides immunoconjugates comprising anti-HER2 antibodies and methods of using the same.
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公开(公告)号：US10314846B2
公开(公告)日：2019-06-11
申请号：US15438418
申请日：2017-02-21
申请人： GENENTECH, INC.
发明人： Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC分类号： A61K39/395 , A61K31/5517 , A61K47/68 , C07K16/00 , C07K16/32
摘要： The invention provides immunoconjugates comprising anti-HER2 antibodies and methods of using the same.
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公开(公告)号：US20160368994A1
公开(公告)日：2016-12-22
申请号：US15182327
申请日：2016-06-14
申请人： Genentech, Inc.
发明人： Robert F. Kelley , Steven R. Leong , Wei-Ching Liang , Mary Mathieu , Andrew G. Polson , Bing Zheng , Xiaocheng Chen , Cecilia Pui Chi Chiu , Mark S. Dennis , Allen Ebens , Yan Wu
IPC分类号： C07K16/28 , A61K45/06 , A61K39/395
CPC分类号： C07K16/2851 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/507 , A61K2039/57 , C07K16/2803 , C07K16/2809 , C07K16/2827 , C07K16/3061 , C07K2317/14 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/40 , C07K2317/41 , C07K2317/52 , C07K2317/526 , C07K2317/55 , C07K2317/56 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/90 , C07K2317/92 , C07K2317/94
摘要： The present invention relates to anti-CLL-1 antibodies including anti-CLL-1 antibodies comprising a CLL-1 binding domain and a CD3 binding domain (e.g., anti-CLL-1/CD3 T cell dependent bispecific (TDB) antibody) and methods of using the same.
摘要翻译： 本发明涉及包含CLL-1结合结构域和CD3结合结构域（例如，抗CLL-1 / CD3T细胞依赖性双特异性（TDB）抗体）的抗CLL-1抗体的抗CLL-1抗体， 使用方法
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公开(公告)号：US11466087B2
公开(公告)日：2022-10-11
申请号：US16658706
申请日：2019-10-21
申请人： Genentech, Inc.
发明人： Robert F. Kelley , Steven R. Leong , Wei-Ching Liang , Mary Mathieu , Andrew G. Polson , Bing Zheng , Xiaocheng Chen , Cecilia Pui Chi Chiu , Mark S. Dennis , Allen Ebens , Yan Wu
IPC分类号： A61K39/395 , C07K16/28 , C07K16/30 , A61K45/06 , A61K39/00
摘要： The present invention relates to anti-CLL-1 antibodies including anti-CLL-1 antibodies comprising a CLL-1 binding domain and a CD3 binding domain (e.g., anti-CLL-1/CD3 T cell dependent bispecific (TDB) antibody) and methods of using the same.
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公开(公告)号：US20200148774A1
公开(公告)日：2020-05-14
申请号：US16658706
申请日：2019-10-21
申请人： Genentech, Inc.
发明人： Robert F. Kelley , Steven R. Leong , Wei-Ching Liang , Mary Mathieu , Andrew G. Polson , Bing Zheng , Xiaocheng Chen , Cecilia Pui Chi Chiu , Mark S. Dennis , Allen Ebens , Yan Wu
IPC分类号： C07K16/28 , C07K16/30 , A61K39/395 , A61K45/06
摘要： The present invention relates to anti-CLL-1 antibodies including anti-CLL-1 antibodies comprising a CLL-1 binding domain and a CD3 binding domain (e.g., anti-CLL-1/CD3 T cell dependent bispecific (TDB) antibody) and methods of using the same.
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公开(公告)号：US10556966B2
公开(公告)日：2020-02-11
申请号：US16170819
申请日：2018-10-25
申请人： Genentech, Inc.
发明人： Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC分类号： C07K16/32 , A61K47/68 , A61K39/395 , C07K16/28 , G01N33/574 , A61K31/5517 , A61K31/675 , A61K31/704 , A61K49/00 , C07K16/30
摘要： The invention provides anti-HER2 antibodies and immunoconjugates and methods of using the same.
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