公开(公告)号：US20210332142A1

公开(公告)日：2021-10-28

申请号：US17208292

申请日：2021-03-22

Applicant: Genentech, Inc.

Inventor： Minhong YAN ,  Gu ZHANG ,  Nicholas John AGARD ,  Danielle Marie DICARA ,  Philip E. HASS ,  Julie Q. HANG ,  Erin L. CHRISTENSEN ,  Robert Paul MORSE ,  Sarah SANOWAR ,  Vittal SHIVVA

IPC: C07K16/28 ,  A61K47/68 ,  A61K47/60 ,  A61K45/06 ,  A61K39/395 ,  A61K9/00 ,  A61P27/02

Abstract: The invention provides Tie-2 antibodies and fragments thereof and conjugates and methods of using the same.

公开(公告)号：US20210002361A1

公开(公告)日：2021-01-07

申请号：US16903300

申请日：2020-06-16

Applicant: Genentech, Inc.

Inventor： Philip E. HASS ,  Meredith HAZEN ,  Yi-Chun HSIAO ,  Rajita KHOSLA ,  Gerald R. NAKAMURA ,  Dhaya SESHASAYEE ,  Menno VAN LOOKEREN CAMPAGNE ,  Hongkang XI ,  Wenwu ZHAI ,  Jack BEVERS, III ,  Nancy CHIANG

IPC: C07K16/24 ,  C12N15/63 ,  C07K16/22 ,  C07K16/40

Abstract: The invention provides interleukin-33 (IL-33) antibodies and methods of using the same.

公开(公告)号：US20190177388A1

公开(公告)日：2019-06-13

申请号：US16196823

申请日：2018-11-20

Applicant: Genentech, Inc.

Inventor： Justin SCHEER ,  Wenjun OUYANG ,  Richard VANDLEN ,  Philip E. HASS ,  Eric Gary STEFANICH ,  Ganesh A. KOLUMAM ,  Xiaoting WANG ,  Jed ROSS ,  Nicholas VAN BRUGGEN ,  Wyne P. LEE

IPC: C07K14/54 ,  A61K38/20 ,  A61K47/38 ,  C07K16/28

Abstract: The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.

公开(公告)号：US20190092852A1

公开(公告)日：2019-03-28

申请号：US16119667

申请日：2018-08-31

Applicant: Genentech, Inc.

Inventor： Philip E. HASS ,  Meredith HAZEN ,  Yi-Chun HSIAO ,  Rajita KHOSLA ,  Gerald R. NAKAMURA ,  Dhaya SESHASAYEE ,  Menno VAN LOOKEREN CAMPAGNE ,  Hongkang XI ,  Wenwu ZHAI ,  Jack BEVERS, III ,  Nancy CHIANG

IPC: C07K16/24 ,  C07K16/40 ,  C07K16/22 ,  A61K39/00

Abstract: The invention provides interleukin-33 (IL-33) antibodies and methods of using the same.

公开(公告)号：US20180362608A1

公开(公告)日：2018-12-20

申请号：US15801867

申请日：2017-11-02

Applicant: Genentech, Inc.

Inventor： Justin SCHEER ,  Wenjun OUYANG ,  Richard VANDLEN ,  Philip E. HASS ,  Eric Gary STEFANICH ,  Ganesh A. KOLUMAM ,  Xiaoting WANG ,  Jed ROSS ,  Nicholas VAN BRUGGEN ,  Wyne P. LEE

IPC: C07K14/54 ,  A61K47/38 ,  A61K38/20 ,  C07K16/28 ,  A61K38/00

Abstract: The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.

公开(公告)号：US20160168242A1

公开(公告)日：2016-06-16

申请号：US14937778

申请日：2015-11-10

Applicant: GENENTECH, INC.

Inventor： Philip E. HASS ,  Meredith HAZEN ,  Yi-Chun HSIAO ,  Rajita KHOSLA ,  Gerald R. NAKAMURA ,  Dhaya SESHASAYEE ,  Menno VAN LOOKEREN CAMPAGNE ,  Hongkang XI ,  Wenwu ZHAI ,  Jack BEVERS, III ,  Nancy CHIANG

IPC: C07K16/24 ,  C07K16/22 ,  C07K16/40

CPC classification number: C07K16/244 ,  A61K2039/507 ,  C07K16/22 ,  C07K16/40 ,  C07K2317/14 ,  C07K2317/24 ,  C07K2317/31 ,  C07K2317/41 ,  C07K2317/53 ,  C07K2317/54 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/76 ,  C07K2317/92

Abstract: The invention provides interleukin-33 (IL-33) antibodies and methods of using the same.

Abstract translation: 本发明提供白细胞介素-33（IL-33）抗体及其使用方法。