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    NEUROSTIMULATOR CONFIGURED TO SENSE EVOKED POTENTIALS IN PERIPHERAL NERVES
    12.
    发明申请
    NEUROSTIMULATOR CONFIGURED TO SENSE EVOKED POTENTIALS IN PERIPHERAL NERVES 有权
    神经细胞被配置为感知外周神经中发生的潜能

    公开(公告)号：US20160144188A1

    公开(公告)日：2016-05-26

    申请号：US15001327

    申请日：2016-01-20

    Applicant: Greatbatch Ltd.

    Inventor： Joey Chen ,  Kerry Bradley ,  Leslie Halberg

    IPC: A61N1/36

    CPC classification number: A61N1/0551 ,  A61B5/064 ,  A61B8/0841 ,  A61N1/05 ,  A61N1/0553 ,  A61N1/36017 ,  A61N1/36021 ,  A61N1/36071 ,  A61N1/36125 ,  A61N1/36139 ,  A61N1/36146 ,  A61N1/36153 ,  A61N1/37223 ,  A61N1/37235 ,  A61N1/37252 ,  A61N1/3752 ,  A61N1/3787

    Abstract: A patient is detected to be in a first posture state. In response to the patient being detected to be in the first posture state, a first electrical stimulation therapy is applied to a body region of the patient by a pulse generator implanted in the patient. The patient is detected to be in a second posture state. In response to the patient being detected to be in the second posture state that is different from the first posture state, a second electrical stimulation therapy is applied to the body region of the patient by the pulse generator. The second electrical stimulation therapy is different from the first electrical stimulation therapy.

    Abstract translation: 检测到患者处于第一姿势状态。 响应于检测到患者处于第一姿势状态，通过植入患者体内的脉冲发生器对患者的身体区域施加第一电刺激治疗。 检测到患者处于第二姿势状态。 响应于检测到患者处于与第一姿势状态不同的第二姿势状态，通过脉冲发生器对患者的身体区域施加第二电刺激治疗。 第二次电刺激治疗与第一次电刺激治疗不同。

    SYSTEM AND METHOD FOR IMPROVING NERVE FINDING FOR PERIPHERAL NERVE STIMULATION
    13.
    发明申请
    SYSTEM AND METHOD FOR IMPROVING NERVE FINDING FOR PERIPHERAL NERVE STIMULATION 有权
    用于改善外周神经刺激的神经发现的系统和方法

    公开(公告)号：US20150012067A1

    公开(公告)日：2015-01-08

    申请号：US14322172

    申请日：2014-07-02

    Applicant: Greatbatch Ltd.

    Inventor： Kerry Bradley ,  Leslie Halberg

    IPC: A61N1/36

    CPC classification number: A61N1/0551 ,  A61B5/064 ,  A61B8/0841 ,  A61N1/05 ,  A61N1/0553 ,  A61N1/36017 ,  A61N1/36021 ,  A61N1/36071 ,  A61N1/36125 ,  A61N1/36139 ,  A61N1/36146 ,  A61N1/36153 ,  A61N1/37223 ,  A61N1/37235 ,  A61N1/37252 ,  A61N1/3752 ,  A61N1/3787

    Abstract: A method of identifying a location for applying a stimulation therapy to treat a patient includes stimulating a first body region of the patient transcutaneously via a stimulus generator. The body region contains a first portion of a nerve that has an elongate shape. In response to the stimulating, action potentials received from a second portion of the nerve are monitored over a period of time. The second portion of the nerve is in a second body region of the patient that is located remotely from the first body region. Based on the monitoring, an optimized location of the second portion of the nerve is determined for applying the stimulation therapy to treat the first body region.

    Abstract translation: 识别用于施加刺激疗法以治疗患者的位置的方法包括通过刺激发生器经皮刺激患者的第一身体区域。 身体区域包含具有细长形状的神经的第一部分。 响应于刺激，在一段时间内监测从神经的第二部分接收的动作电位。 神经的第二部分位于远离第一身体区域的患者的第二身体区域中。 基于监测，确定神经的第二部分的优化位置以施加刺激疗法来治疗第一身体区域。

    Paddle Lead Maximizing Lateral Target Points Across a Peripheral Nerve
    16.
    发明申请
    Paddle Lead Maximizing Lateral Target Points Across a Peripheral Nerve 有权
    桨导线最大化外周神经的横向目标点

    公开(公告)号：US20150012071A1

    公开(公告)日：2015-01-08

    申请号：US14322455

    申请日：2014-07-02

    Applicant: Greatbatch Ltd.

    Inventor： Kerry Bradley ,  Leslie Halberg

    IPC: A61N1/05

    CPC classification number: A61N1/0551 ,  A61B5/064 ,  A61B8/0841 ,  A61N1/05 ,  A61N1/0553 ,  A61N1/36017 ,  A61N1/36021 ,  A61N1/36071 ,  A61N1/36125 ,  A61N1/36139 ,  A61N1/36146 ,  A61N1/36153 ,  A61N1/37223 ,  A61N1/37235 ,  A61N1/37252 ,  A61N1/3752 ,  A61N1/3787

    Abstract: The present disclosure involves a medical system. The medical system an implantable lead configured to deliver an electrical stimulation therapy for a patient. The lead includes an elongate lead body that is configured to be coupled to a pulse generator that generates electrical stimulations pulses as part of the electrical stimulation therapy. The lead also includes a paddle coupled to the lead body. The paddle contains a plurality of electrodes that are each configured to deliver the electrical stimulation pulses to the patient. The plurality of electrodes is arranged into at least three columns that each include a respective subset of the electrodes. The plurality of electrodes each includes a unique centerline, wherein the centerlines extend in directions transverse to the columns.

    Abstract translation: 本公开涉及医疗系统。 该医疗系统是可植入引线，其被配置为递送针对患者的电刺激疗法。 引线包括细长引线体，其被配置为耦合到脉冲发生器，其产生作为电刺激治疗的一部分的电刺激脉冲。 引线还包括耦合到引线主体的桨。 桨包含多个电极，每个电极被配置为将电刺激脉冲递送给患者。 多个电极布置成至少三个列，每个列包括电极的相应子集。 多个电极各自包括唯一的中心线，其中中心线在横向于列的方向上延伸。

    Neurostimulator Configured to Sense Evoked Potentials in Peripheral Nerves
    17.
    发明申请
    Neurostimulator Configured to Sense Evoked Potentials in Peripheral Nerves 有权
    神经刺激器配置为外围神经中的感觉诱发电位

    公开(公告)号：US20150012064A1

    公开(公告)日：2015-01-08

    申请号：US14322716

    申请日：2014-07-02

    Applicant: Greatbatch Ltd.

    Inventor： Joey Chen ,  Kerry Bradley ,  Leslie Halberg

    IPC: A61N1/36 ,  A61N1/372

    CPC classification number: A61N1/0551 ,  A61B5/064 ,  A61B8/0841 ,  A61N1/05 ,  A61N1/0553 ,  A61N1/36017 ,  A61N1/36021 ,  A61N1/36071 ,  A61N1/36125 ,  A61N1/36139 ,  A61N1/36146 ,  A61N1/36153 ,  A61N1/37223 ,  A61N1/37235 ,  A61N1/37252 ,  A61N1/3752 ,  A61N1/3787

    Abstract: A method of providing stimulation therapy to a patient includes performing first and second calibration processes in first and second patient posture states, respectively. The first and second calibration processes respectively associates a sensation experienced by a patient, in the respective patient posture states, with first and second amounts of an evoked potential, respectively, and also with first and second values of a stimulation parameter to achieve the first and second amounts of evoked potential, respectively. Thereafter, a current patient posture state is detected. If the current patient posture state is detected as the first patient posture state, stimulation therapy is applied to the patient using the first value of the stimulation parameter as an initial value. If the current patient posture state is detected as the second patient posture state, stimulation therapy is applied to the patient using the second value of the stimulation parameter as the initial value.

    Abstract translation: 向患者提供刺激治疗的方法包括分别在第一和第二患者姿势状态下执行第一和第二校准过程。 第一和第二校准过程分别将患者经历的各种患者姿势状态中的感觉分别与诱发电位的第一和第二量相关联，以及刺激参数的第一和第二值以实现第一和第 第二量诱发电位。 此后，检测当前的患者姿势状态。 如果当前患者姿势状态被检测为第一患者姿势状态，则使用刺激参数的第一值作为初始值对患者施加刺激治疗。 如果当前患者姿势状态被检测为第二患者姿势状态，则使用刺激参数的第二值作为初始值对患者施加刺激治疗。

    System and method for selective and maintained activation of sensory peripheral nerve fibers
    19.
    发明授权
    System and method for selective and maintained activation of sensory peripheral nerve fibers 有权
    感觉周围神经纤维选择性和维持活化的系统和方法

    公开(公告)号：US09415211B2

    公开(公告)日：2016-08-16

    申请号：US14321914

    申请日：2014-07-02

    Applicant: Greatbatch Ltd.

    Inventor： Kerry Bradley ,  Leslie Halberg

    IPC: A61N1/05 ,  A61B5/06 ,  A61B8/08 ,  A61N1/36 ,  A61N1/372

    CPC classification number: A61N1/0551 ,  A61B5/064 ,  A61B8/0841 ,  A61N1/05 ,  A61N1/0553 ,  A61N1/36017 ,  A61N1/36021 ,  A61N1/36071 ,  A61N1/36125 ,  A61N1/36139 ,  A61N1/36146 ,  A61N1/36153 ,  A61N1/37223 ,  A61N1/37235 ,  A61N1/37252 ,  A61N1/3752 ,  A61N1/3787

    Abstract: A method of establishing a stimulation treatment protocol includes delivering electrical stimulation to a nerve site of the patient. The electrical stimulation is delivered using a stimulation configuration with respect to one or more of the following: activation of a subset of a plurality of electrodes on a lead, electrode polarity for the activated electrodes, stimulation pulse width, and stimulation pulse amplitude. An action potential evoked from the nerve site in response to the electrical stimulation is measured. The action potential includes a sensory fiber contribution and a motor fiber contribution. Both the sensory fiber contribution and the motor fiber contribution are measured. The delivering and the measuring are repeated for a plurality of cycles. Each cycle is performed using a different stimulation configuration. The stimulation configuration that offers a greatest sensory fiber contribution relative to the motor fiber contribution is recommended as a candidate for optimized stimulation configuration.

    Abstract translation: 建立刺激治疗方案的方法包括将电刺激递送到患者的神经部位。 使用关于以下中的一个或多个的刺激配置来递送电刺激：激活引线上的多个电极的子集，激活电极的电极极性，刺激脉冲宽度和刺激脉冲幅度。 测量响应于电刺激从神经部位诱发的动作电位。 动作电位包括感官纤维的贡献和运动纤维的贡献。 测量感官纤维的贡献和运动纤维的贡献。 交付和测量重复多个周期。 每个循环使用不同的刺激配置进行。 作为优化刺激配置的候选者，推荐提供相对于马达纤维贡献的最大感官纤维贡献的刺激配置。

    Systems and Methods for Reducing Power Consumption in an Implantable Medical Device
    20.
    发明申请
    Systems and Methods for Reducing Power Consumption in an Implantable Medical Device 有权
    降低可植入医疗器械功耗的系统和方法

    公开(公告)号：US20150012062A1

    公开(公告)日：2015-01-08

    申请号：US14321234

    申请日：2014-07-01

    Applicant: Greatbatch Ltd.

    Inventor： Joey Chen ,  Kerry Bradley ,  Leslie Halberg

    IPC: A61N1/372

    CPC classification number: A61N1/0551 ,  A61B5/064 ,  A61B8/0841 ,  A61N1/05 ,  A61N1/0553 ,  A61N1/36017 ,  A61N1/36021 ,  A61N1/36071 ,  A61N1/36125 ,  A61N1/36139 ,  A61N1/36146 ,  A61N1/36153 ,  A61N1/37223 ,  A61N1/37235 ,  A61N1/37252 ,  A61N1/3752 ,  A61N1/3787

    Abstract: A medical device for providing a stimulation therapy includes stimulation circuitry configured to provide a plurality of electrical pulses to be delivered to a patient. The stimulation circuitry contains a microcontroller configured to generate the electrical pulses. Each electrical pulse includes a primary phase, an interphase after the primary phase, and a recovery phase after the primary phase. Consecutive electrical pulses are separated by a standby period. The microcontroller is configured to operate in an active mode during at least one of: the primary phase and the interphase. The microcontroller is configured to operate in a power-conservation mode during a substantial majority of the standby period. The microcontroller consumes substantially less power when operating in the power-conservation mode than in the active mode.

    Abstract translation: 用于提供刺激疗法的医疗装置包括被配置为提供要传送给患者的多个电脉冲的刺激电路。 刺激电路包含被配置为产生电脉冲的微控制器。 每个电脉冲包括主相，主相后的相间和主相之后的恢复阶段。 连续的电脉冲在待机时间间隔。 微控制器被配置为在主要阶段和相间的至少一个期间以活动模式操作。 微控制器被配置为在大部分待机期间以功率节省模式工作。 当在功率节省模式下工作时，微控制器的功耗远低于主动模式。

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