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公开(公告)号：US10463852B2
公开(公告)日：2019-11-05
申请号：US15657968
申请日：2017-07-24
Applicant: Greatbatch Ltd.
Inventor： Kerry Bradley , Leslie Halberg
Abstract: Via a pulse generator, a trigger signal is generated. The trigger signal indicates one or more stimulation pulses are about to be delivered, or is being delivered, to a patient. The trigger signal is sent to a measurement instrument. Via the pulse generator, the one or more stimulation pulses are generated. The one or more stimulation pulses are delivered to the patient. With the measurement instrument and in response to the trigger signal, one or more action potentials are measured. The one or more action potentials are produced by the patient in response to the one or more stimulation pulses.
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2.发明授权公开(公告)号：US09248279B2
公开(公告)日：2016-02-02
申请号：US14322716
申请日：2014-07-02
Applicant: Greatbatch Ltd.
Inventor： Joey Chen , Kerry Bradley , Leslie Halberg
CPC classification number: A61N1/0551 , A61B5/064 , A61B8/0841 , A61N1/05 , A61N1/0553 , A61N1/36017 , A61N1/36021 , A61N1/36071 , A61N1/36125 , A61N1/36139 , A61N1/36146 , A61N1/36153 , A61N1/37223 , A61N1/37235 , A61N1/37252 , A61N1/3752 , A61N1/3787
Abstract: A method of providing stimulation therapy to a patient includes performing first and second calibration processes in first and second patient posture states, respectively. The first and second calibration processes respectively associates a sensation experienced by a patient, in the respective patient posture states, with first and second amounts of an evoked potential, respectively, and also with first and second values of a stimulation parameter to achieve the first and second amounts of evoked potential, respectively. Thereafter, a current patient posture state is detected. If the current patient posture state is detected as the first patient posture state, stimulation therapy is applied to the patient using the first value of the stimulation parameter as an initial value. If the current patient posture state is detected as the second patient posture state, stimulation therapy is applied to the patient using the second value of the stimulation parameter as the initial value.
Abstract translation: 向患者提供刺激治疗的方法包括分别在第一和第二患者姿势状态下执行第一和第二校准过程。 第一和第二校准过程分别将患者经历的各种患者姿势状态中的感觉分别与诱发电位的第一和第二量相关联，以及刺激参数的第一和第二值以实现第一和第 第二量诱发电位。 此后，检测当前的患者姿势状态。 如果当前患者姿势状态被检测为第一患者姿势状态，则使用刺激参数的第一值作为初始值对患者施加刺激治疗。 如果当前患者姿势状态被检测为第二患者姿势状态，则使用刺激参数的第二值作为初始值对患者施加刺激治疗。
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公开(公告)号：US09744347B2
公开(公告)日：2017-08-29
申请号：US14321234
申请日：2014-07-01
Applicant: Greatbatch Ltd.
Inventor： Joey Chen , Kerry Bradley , Leslie Halberg
CPC classification number: A61N1/0551 , A61B5/064 , A61B8/0841 , A61N1/05 , A61N1/0553 , A61N1/36017 , A61N1/36021 , A61N1/36071 , A61N1/36125 , A61N1/36139 , A61N1/36146 , A61N1/36153 , A61N1/37223 , A61N1/37235 , A61N1/37252 , A61N1/3752 , A61N1/3787
Abstract: A medical device for providing a stimulation therapy includes stimulation circuitry configured to provide a plurality of electrical pulses to be delivered to a patient. The stimulation circuitry contains a microcontroller configured to generate the electrical pulses. Each electrical pulse includes a primary phase, an interphase after the primary phase, and a recovery phase after the primary phase. Consecutive electrical pulses are separated by a standby period. The microcontroller is configured to operate in an active mode during at least one of: the primary phase and the interphase. The microcontroller is configured to operate in a power-conservation mode during a substantial majority of the standby period. The microcontroller consumes substantially less power when operating in the power-conservation mode than in the active mode.
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公开(公告)号：US20150012071A1
公开(公告)日：2015-01-08
申请号：US14322455
申请日：2014-07-02
Applicant: Greatbatch Ltd.
Inventor： Kerry Bradley , Leslie Halberg
IPC: A61N1/05
CPC classification number: A61N1/0551 , A61B5/064 , A61B8/0841 , A61N1/05 , A61N1/0553 , A61N1/36017 , A61N1/36021 , A61N1/36071 , A61N1/36125 , A61N1/36139 , A61N1/36146 , A61N1/36153 , A61N1/37223 , A61N1/37235 , A61N1/37252 , A61N1/3752 , A61N1/3787
Abstract: The present disclosure involves a medical system. The medical system an implantable lead configured to deliver an electrical stimulation therapy for a patient. The lead includes an elongate lead body that is configured to be coupled to a pulse generator that generates electrical stimulations pulses as part of the electrical stimulation therapy. The lead also includes a paddle coupled to the lead body. The paddle contains a plurality of electrodes that are each configured to deliver the electrical stimulation pulses to the patient. The plurality of electrodes is arranged into at least three columns that each include a respective subset of the electrodes. The plurality of electrodes each includes a unique centerline, wherein the centerlines extend in directions transverse to the columns.
Abstract translation: 本公开涉及医疗系统。 该医疗系统是可植入引线，其被配置为递送针对患者的电刺激疗法。 引线包括细长引线体，其被配置为耦合到脉冲发生器，其产生作为电刺激治疗的一部分的电刺激脉冲。 引线还包括耦合到引线主体的桨。 桨包含多个电极，每个电极被配置为将电刺激脉冲递送给患者。 多个电极布置成至少三个列，每个列包括电极的相应子集。 多个电极各自包括唯一的中心线，其中中心线在横向于列的方向上延伸。
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5.发明申请公开(公告)号：US20150012064A1
公开(公告)日：2015-01-08
申请号：US14322716
申请日：2014-07-02
Applicant: Greatbatch Ltd.
Inventor： Joey Chen , Kerry Bradley , Leslie Halberg
CPC classification number: A61N1/0551 , A61B5/064 , A61B8/0841 , A61N1/05 , A61N1/0553 , A61N1/36017 , A61N1/36021 , A61N1/36071 , A61N1/36125 , A61N1/36139 , A61N1/36146 , A61N1/36153 , A61N1/37223 , A61N1/37235 , A61N1/37252 , A61N1/3752 , A61N1/3787
Abstract: A method of providing stimulation therapy to a patient includes performing first and second calibration processes in first and second patient posture states, respectively. The first and second calibration processes respectively associates a sensation experienced by a patient, in the respective patient posture states, with first and second amounts of an evoked potential, respectively, and also with first and second values of a stimulation parameter to achieve the first and second amounts of evoked potential, respectively. Thereafter, a current patient posture state is detected. If the current patient posture state is detected as the first patient posture state, stimulation therapy is applied to the patient using the first value of the stimulation parameter as an initial value. If the current patient posture state is detected as the second patient posture state, stimulation therapy is applied to the patient using the second value of the stimulation parameter as the initial value.
Abstract translation: 向患者提供刺激治疗的方法包括分别在第一和第二患者姿势状态下执行第一和第二校准过程。 第一和第二校准过程分别将患者经历的各种患者姿势状态中的感觉分别与诱发电位的第一和第二量相关联，以及刺激参数的第一和第二值以实现第一和第 第二量诱发电位。 此后，检测当前的患者姿势状态。 如果当前患者姿势状态被检测为第一患者姿势状态，则使用刺激参数的第一值作为初始值对患者施加刺激治疗。 如果当前患者姿势状态被检测为第二患者姿势状态，则使用刺激参数的第二值作为初始值对患者施加刺激治疗。
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Patent Agency Ranking
公开(公告)号：US10813744B2
公开(公告)日：2020-10-27
申请号：US15757315
申请日：2015-09-03
Applicant: Elenza, Inc. , Greatbatch Ltd.
Inventor： Amitava Gupta , Rudy Mazzocchi , Roel Trip , Brian Peterson , George Cintra , Joey Chen , Leslie Halberg
IPC: A61F2/16 , H02J50/12 , H02J7/02 , H02J50/70 , H02J50/80 , G02C11/00 , A61F9/007 , H01F38/14 , H02J7/34 , H02J7/35
Abstract: An intraocular implant (IOI) includes a lens structure with variable optical power, a sensor that detects an optical accommodation response, a rechargeable power storage device, a recharging interface, a wireless communication interface, and a controller. The controller can receive information from the sensor indicating an optical accommodation response, control the lens structure to vary the variable optical power based on the information received from the sensor, control the recharging interface to recharge the rechargeable power storage device, and further control the recharging interface to receive power for operation of the IOI, and transmit and receive information through the wireless communication interface.
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7.发明授权公开(公告)号：US09526897B2
公开(公告)日：2016-12-27
申请号：US15001327
申请日：2016-01-20
Applicant: Greatbatch Ltd.
Inventor： Joey Chen , Kerry Bradley , Leslie Halberg
CPC classification number: A61N1/0551 , A61B5/064 , A61B8/0841 , A61N1/05 , A61N1/0553 , A61N1/36017 , A61N1/36021 , A61N1/36071 , A61N1/36125 , A61N1/36139 , A61N1/36146 , A61N1/36153 , A61N1/37223 , A61N1/37235 , A61N1/37252 , A61N1/3752 , A61N1/3787
Abstract: A patient is detected to be in a first posture state. In response to the patient being detected to be in the first posture state, a first electrical stimulation therapy is applied to a body region of the patient by a pulse generator implanted in the patient. The patient is detected to be in a second posture state. In response to the patient being detected to be in the second posture state that is different from the first posture state, a second electrical stimulation therapy is applied to the body region of the patient by the pulse generator. The second electrical stimulation therapy is different from the first electrical stimulation therapy.
Abstract translation: 检测到患者处于第一姿势状态。 响应于检测到患者处于第一姿势状态，通过植入患者体内的脉冲发生器对患者的身体区域施加第一电刺激治疗。 检测到患者处于第二姿势状态。 响应于检测到患者处于与第一姿势状态不同的第二姿势状态，通过脉冲发生器对患者的身体区域施加第二电刺激治疗。 第二次电刺激治疗与第一次电刺激治疗不同。
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8.发明申请公开(公告)号：US20160144188A1
公开(公告)日：2016-05-26
申请号：US15001327
申请日：2016-01-20
Applicant: Greatbatch Ltd.
Inventor： Joey Chen , Kerry Bradley , Leslie Halberg
IPC: A61N1/36
CPC classification number: A61N1/0551 , A61B5/064 , A61B8/0841 , A61N1/05 , A61N1/0553 , A61N1/36017 , A61N1/36021 , A61N1/36071 , A61N1/36125 , A61N1/36139 , A61N1/36146 , A61N1/36153 , A61N1/37223 , A61N1/37235 , A61N1/37252 , A61N1/3752 , A61N1/3787
Abstract: A patient is detected to be in a first posture state. In response to the patient being detected to be in the first posture state, a first electrical stimulation therapy is applied to a body region of the patient by a pulse generator implanted in the patient. The patient is detected to be in a second posture state. In response to the patient being detected to be in the second posture state that is different from the first posture state, a second electrical stimulation therapy is applied to the body region of the patient by the pulse generator. The second electrical stimulation therapy is different from the first electrical stimulation therapy.
Abstract translation: 检测到患者处于第一姿势状态。 响应于检测到患者处于第一姿势状态，通过植入患者体内的脉冲发生器对患者的身体区域施加第一电刺激治疗。 检测到患者处于第二姿势状态。 响应于检测到患者处于与第一姿势状态不同的第二姿势状态，通过脉冲发生器对患者的身体区域施加第二电刺激治疗。 第二次电刺激治疗与第一次电刺激治疗不同。
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9.发明申请SYSTEM AND METHOD FOR IMPROVING NERVE FINDING FOR PERIPHERAL NERVE STIMULATION 有权用于改善外周神经刺激的神经发现的系统和方法公开(公告)号：US20150012067A1
公开(公告)日：2015-01-08
申请号：US14322172
申请日：2014-07-02
Applicant: Greatbatch Ltd.
Inventor： Kerry Bradley , Leslie Halberg
IPC: A61N1/36
CPC classification number: A61N1/0551 , A61B5/064 , A61B8/0841 , A61N1/05 , A61N1/0553 , A61N1/36017 , A61N1/36021 , A61N1/36071 , A61N1/36125 , A61N1/36139 , A61N1/36146 , A61N1/36153 , A61N1/37223 , A61N1/37235 , A61N1/37252 , A61N1/3752 , A61N1/3787
Abstract: A method of identifying a location for applying a stimulation therapy to treat a patient includes stimulating a first body region of the patient transcutaneously via a stimulus generator. The body region contains a first portion of a nerve that has an elongate shape. In response to the stimulating, action potentials received from a second portion of the nerve are monitored over a period of time. The second portion of the nerve is in a second body region of the patient that is located remotely from the first body region. Based on the monitoring, an optimized location of the second portion of the nerve is determined for applying the stimulation therapy to treat the first body region.
Abstract translation: 识别用于施加刺激疗法以治疗患者的位置的方法包括通过刺激发生器经皮刺激患者的第一身体区域。 身体区域包含具有细长形状的神经的第一部分。 响应于刺激，在一段时间内监测从神经的第二部分接收的动作电位。 神经的第二部分位于远离第一身体区域的患者的第二身体区域中。 基于监测，确定神经的第二部分的优化位置以施加刺激疗法来治疗第一身体区域。
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10.发明授权公开(公告)号：US09636497B2
公开(公告)日：2017-05-02
申请号：US15180613
申请日：2016-06-13
Applicant: Greatbatch Ltd.
Inventor： Kerry Bradley , Leslie Halberg
CPC classification number: A61N1/0551 , A61B5/064 , A61B8/0841 , A61N1/05 , A61N1/0553 , A61N1/36017 , A61N1/36021 , A61N1/36071 , A61N1/36125 , A61N1/36139 , A61N1/36146 , A61N1/36153 , A61N1/37223 , A61N1/37235 , A61N1/37252 , A61N1/3752 , A61N1/3787
Abstract: Electrical stimulation is applied to a patient at least in part via a pulse generator. A motor fiber component of an action potential that is evoked in response to the electrical stimulation is measured. A sensory fiber component of the action potential is also measured. A relationship between the motor fiber component and the sensory fiber component is determined. For example, a ratio between the sensory fiber component and the motor fiber component may be calculated, or the absolute sizes of the sensory fiber component and the motor fiber component may be compared. Based on the determined relationship between the motor and sensory fiber components, a paresthesia of the patient is estimated.
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