公开(公告)号：US11204432B2

公开(公告)日：2021-12-21

申请号：US16764066

申请日：2018-06-18

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Tadashi Maruno ,  Eiji Toda ,  Mao Nakajima ,  Teruo Takahashi ,  Takafumi Higuchi

IPC: G01T1/24 ,  H04N5/3745 ,  H04N5/374 ,  H04N5/376 ,  H04N5/363 ,  H04N5/378 ,  G01T1/208

Abstract: A photon counting device includes a plurality of pixels each including a photoelectric conversion element configured to convert input light to charge, and an amplifier configured to amplify the charge converted by the photoelectric conversion element and convert the charge to a voltage, an A/D converter configured to convert the voltages output from the amplifiers of the plurality of pixels to digital values; and a conversion unit configured to convert the digital value output from the A/D converter to the number of photons by referring to reference data, for each of the plurality of pixels, and the reference data is created based on a gain and an offset value for each of the plurality of pixels.

公开(公告)号：US10362245B2

公开(公告)日：2019-07-23

申请号：US16149642

申请日：2018-10-02

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Eiji Toda ,  Takuo Kameyama

IPC: H04N3/14 ,  H04N5/353 ,  G02B21/36 ,  H04N5/359 ,  H04N5/378 ,  H04N5/225 ,  H04N5/232 ,  G02B21/00 ,  H04N5/341 ,  H04N5/235 ,  G02B21/16

Abstract: An image acquisition system 1 includes: a light source 3 which outputs illumination light; an optical scanner 7 which scans a sample S with the illumination light; an optical scanner control unit 9; a detection optical system 15, 17 which focuses fluorescence from the sample S; an imaging device 19 which has a light receiving surface 19c in which a plurality of pixel rows 19d are arranged, and an imaging control section 19b, and which can perform signal readout of each of the plurality of pixel rows 19d from the light receiving surface 19c; and a calculation unit 21 which calculates an interval of signal readout between adjacent pixel rows 19d, based on a moving speed of an illuminated region on the light receiving surface 19c; the imaging control section 19b controls signal readout of each pixel row 19d, based on the interval of the signal readout thus calculated.

公开(公告)号：US09372332B2

公开(公告)日：2016-06-21

申请号：US14413602

申请日：2014-01-22

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Eiji Toda ,  Takuo Kameyama

IPC: G02B21/16 ,  H04N5/225 ,  H04N5/232 ,  H04N3/14 ,  H04N5/378 ,  H04N5/359 ,  G02B21/00 ,  G02B21/36 ,  H04N5/341 ,  H04N5/235 ,  H04N5/353

Abstract: An image acquisition system 1 includes: a light source 3 which outputs illumination light; an optical scanner 7 which scans a sample S with the illumination light; an optical scanner control unit 9; a detection optical system 15, 17 which focuses fluorescence from the sample S; an imaging device 19 which has a light receiving surface 19c in which a plurality of pixel rows 19d are arranged, and an imaging control section 19b, and which can perform signal readout of each of the plurality of pixel rows 19d from the light receiving surface 19c; and a calculation unit 21 which calculates an interval of signal readout between adjacent pixel rows 19d, based on a moving speed of an illuminated region on the light receiving surface 19c; the imaging control section 19b controls signal readout of each pixel row 19d, based on the interval of the signal readout thus calculated.