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    REAGENT CARRIERS FOR FLUIDIC SYSTEMS
    12.
    发明申请
    REAGENT CARRIERS FOR FLUIDIC SYSTEMS 有权

    公开(公告)号：US20210260588A1

    公开(公告)日：2021-08-26

    申请号：US17183897

    申请日：2021-02-24

    申请人： HelixBind, Inc.

    发明人： Alon Singer ,  Ranjit Prakash ,  David Steinmiller

    IPC分类号： B01L3/00

    摘要： Fluidic systems and reagent carriers suitable for storing reagents in a desirable manner are generally provided. In some embodiments, a reagent carrier stores a liquid film comprising a solid reagent and/or stores different reagents in different locations. In some embodiments, a fluidic system comprises a reagent carrier constrained such that it comprises an elongated axis positioned within 30° of a vertical axis of the fluidic reservoir.

    Integrated fluidic devices and related methods
    19.
    发明授权
    Integrated fluidic devices and related methods 有权

    公开(公告)号：US10730041B2

    公开(公告)日：2020-08-04

    申请号：US15458288

    申请日：2017-03-14

    申请人： HelixBind, Inc.

    发明人： Alon Singer ,  Ranjit Prakash

    IPC分类号： B01L3/00 ,  B01D71/34 ,  C12Q1/686 ,  B01L7/00 ,  B01D63/08 ,  B01D69/02

    摘要： Fluidic devices and related methods are generally provided. The fluidic devices described herein may be useful, for example, for diagnostic purposes (e.g., detection of the presence of one or more disease causing bacteria in a patient sample). Unlike certain existing fluidic devices for diagnostic purposes, the fluidic devices and methods described herein may be useful for detecting the presence of numerous disease causing bacteria in a patient sample substantially simultaneously (e.g., in parallel). In some embodiments, the fluidic devices and methods described herein provide highly sensitive detection of microbes in relatively large fluidic samples (e.g., between 0.5 mL and about 5 mL), as compared to certain existing fluidic detection (e.g., microfluidic) devices and methods. In an exemplary embodiment, increased detection sensitivity of microbial pathogens present in a patient sample (e.g., blood) is performed by selectively removing human nucleic acid prior to sensitive detection of microbial infection. In some embodiments, the fluidic device allows for the identification of microbial pathogens directly from unprocessed blood without having to conduct blood culturing processes.

    INTEGRATED FLUIDIC DEVICES AND RELATED METHODS
    20.
    发明申请
    INTEGRATED FLUIDIC DEVICES AND RELATED METHODS 审中-公开

    公开(公告)号：US20170259257A1

    公开(公告)日：2017-09-14

    申请号：US15458288

    申请日：2017-03-14

    申请人： HelixBind, Inc.

    发明人： Alon Singer ,  Ranjit Prakash

    IPC分类号： B01L3/00 ,  B01D71/34 ,  C12Q1/68

    摘要： Fluidic devices and related methods are generally provided. The fluidic devices described herein may be useful, for example, for diagnostic purposes (e.g., detection of the presence of one or more disease causing bacteria in a patient sample). Unlike certain existing fluidic devices for diagnostic purposes, the fluidic devices and methods described herein may be useful for detecting the presence of numerous disease causing bacteria in a patient sample substantially simultaneously (e.g., in parallel). In some embodiments, the fluidic devices and methods described herein provide highly sensitive detection of microbes in relatively large fluidic samples (e.g., between 0.5 mL and about 5 mL), as compared to certain existing fluidic detection (e.g., microfluidic) devices and methods. In an exemplary embodiment, increased detection sensitivity of microbial pathogens present in a patient sample (e.g., blood) is performed by selectively removing human nucleic acid prior to sensitive detection of microbial infection. In some embodiments, the fluidic device allows for the identification of microbial pathogens directly from unprocessed blood without having to conduct blood culturing processes.