公开(公告)号：US20190015652A1

公开(公告)日：2019-01-17

申请号：US16134030

申请日：2018-09-18

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Kazuya KOMINAMI ,  Shinpei NISHIMURA ,  Seiji TOKUMOTO ,  Makoto OGURA ,  Toshiyuki MATSUDO ,  Naoki YAMAMOTO

IPC: A61M37/00 ,  A61N2/00 ,  A61N1/32

Abstract: A microneedle sheet according to an embodiment comprises a plurality of microneedles formed on a sheet substantially along a principal surface of the sheet. The sheet is bent to raise the microneedles from the principal surface, and the raised microneedles pierce a skin.

公开(公告)号：US20170049695A1

公开(公告)日：2017-02-23

申请号：US15119983

申请日：2015-02-19

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Naoki YAMAMOTO ,  Makoto OGURA

IPC: A61K9/00

Abstract: A microneedle sheet according to an embodiment includes a plurality of microneedles formed on a sheet generally along a principal surface of the sheet. The material of the microneedles is selected from among hydroxypropyl methylcellulose, hydroxypropyl cellulose, polyvinyl alcohol, and a graft copolymer of polyvinyl alcohol and polyethylene glycol. The microneedles are raised from the principal surface by bending the sheet, and the raised microneedles pierce skin.

Abstract translation: 根据一个实施方式的微针片包括多个形成在片材的主表面上的片材上的微针。 微针的材料选自羟丙基甲基纤维素，羟丙基纤维素，聚乙烯醇和聚乙烯醇与聚乙二醇的接枝共聚物。 微针通过弯曲片材从主表面凸起，并且凸起的微针刺穿皮肤。

公开(公告)号：US20160206866A1

公开(公告)日：2016-07-21

申请号：US14916354

申请日：2014-09-03

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Naoki YAMAMOTO ,  Makoto OGURA

IPC: A61M37/00

CPC classification number: A61M37/0015 ,  A61M2037/0023 ,  A61M2037/0038 ,  A61M2037/0053

Abstract: A microneedle sheet in an embodiment of the present invention includes a plurality of microneedles formed on a sheet generally along a principal surface of the sheet. The microneedles are configured to rise from the principal surface when the sheet is bent, and the raised microneedles pierce skin. At least some of the microneedles each have a region for exposing a tear formed in the skin in a needle inserted state.

Abstract translation: 本发明的一个实施方案中的微针片包括多个形成在片材的主表面上的片材上的微针。 微针被配置成当片材弯曲时从主表面上升，并且凸起的微针刺穿皮肤。 至少一些微针每个都具有用于在针插入状态下暴露在皮肤中形成的泪液的区域。