公开(公告)号：US20050112602A1

公开(公告)日：2005-05-26

申请号：US10789723

申请日：2004-02-27

申请人： Chul-Wook Kim ,  Jung-Sou Yeo ,  Jung-Gyu Lee ,  Young-Min Song ,  Kwang-Keun Cho ,  Ki-Hwa Chung ,  Il-Suk Kim ,  Sang-Keun Jin ,  Su-Hyun Park ,  Ji-Won Jung ,  Min-Jung Lee ,  Eun-Jung Kwon ,  Eun-Segk Cho ,  Hwok-Rai Cho ,  Sun-Min Shin ,  Hee-Sun Nam ,  Yeon-Hee Hong ,  Sung-Kwang Hong ,  Yang-Su Kang ,  Young-Joo Ha ,  Jeong-Man Rou ,  Suk-Chun Kwack ,  In-Ho Choi ,  Byeong-Woo Kim

发明人： Chul-Wook Kim ,  Jung-Sou Yeo ,  Jung-Gyu Lee ,  Young-Min Song ,  Kwang-Keun Cho ,  Ki-Hwa Chung ,  Il-Suk Kim ,  Sang-Keun Jin ,  Su-Hyun Park ,  Ji-Won Jung ,  Min-Jung Lee ,  Eun-Jung Kwon ,  Eun-Segk Cho ,  Hwok-Rai Cho ,  Sun-Min Shin ,  Hee-Sun Nam ,  Yeon-Hee Hong ,  Sung-Kwang Hong ,  Yang-Su Kang ,  Young-Joo Ha ,  Jeong-Man Rou ,  Suk-Chun Kwack ,  In-Ho Choi ,  Byeong-Woo Kim

IPC分类号： C12M1/34 ,  C12Q1/68 ,  C40B40/06 ,  C40B60/14

CPC分类号： C12Q1/6888 ,  B01J2219/00364 ,  B01J2219/00378 ,  B01J2219/00387 ,  B01J2219/00432 ,  B01J2219/00527 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/00612 ,  B01J2219/00637 ,  B01J2219/00659 ,  B01J2219/00677 ,  B01J2219/00722 ,  C12Q2600/158 ,  C40B40/06 ,  C40B60/14

摘要： The present invention relates to a cDNA chip for screening and function analysis of swine genes and provides a cDNA chip comprising a probe to detect marker genes specifically expressed in the muscle and fat tissues of swine, in which the probe is capable of complementarily bind to the marker genes. Also, the present invention provides expression profiles of marker genes which are related to economic traits of swine by using the cDNA chip according to the present invention. Therefore, the cDNA chip according to the present invention can be used for the comparison of genetic expression according to swine breeds and tissues, genetic mutation screening, genetic polymorphism interpretation, development of new drugs for disease treatment and disease diagnosis, swine improvement.

摘要翻译： 本发明涉及用于猪基因筛选和功能分析的cDNA芯片，并且提供了包含探针的cDNA芯片，以检测在猪的肌肉和脂肪组织中特异性表达的标记基因，其中探针能够互补结合 标记基因。 此外，本发明通过使用根据本发明的cDNA芯片提供与猪的经济性状相关的标记基因的表达谱。 因此，根据本发明的cDNA芯片可用于比较猪品种和组织的基因表达，遗传突变筛选，遗传多态性解释，疾病治疗和疾病诊断用新药的发展，猪的改良。

公开(公告)号：US20050112599A1

公开(公告)日：2005-05-26

申请号：US10788562

申请日：2004-02-27

申请人： Chul-Wook Kim ,  Jung-Sou Yeo ,  Jung-Gyu Lee ,  Young-Min Song ,  Kwang-Keun Cho ,  Ki-Hwa Chung ,  Il-Suk Kim ,  Sang-Keun Jin ,  Su-Hyun Park ,  Ji-Won Jung ,  Min-Jung Lee ,  Eun-Jung Kwon ,  Eun-Segk Cho ,  Hwok-Rai Cho ,  Sun-Min Shin ,  Hee-Sun Nam ,  Yeon-Hee Hong ,  Sung-Kwang Hong ,  Yang-Su Kang ,  Young-Joo Ha ,  Jeong-Man Rou ,  Suk-Chun Kwack ,  In-Ho Choi ,  Byeong-Woo Kim

发明人： Chul-Wook Kim ,  Jung-Sou Yeo ,  Jung-Gyu Lee ,  Young-Min Song ,  Kwang-Keun Cho ,  Ki-Hwa Chung ,  Il-Suk Kim ,  Sang-Keun Jin ,  Su-Hyun Park ,  Ji-Won Jung ,  Min-Jung Lee ,  Eun-Jung Kwon ,  Eun-Segk Cho ,  Hwok-Rai Cho ,  Sun-Min Shin ,  Hee-Sun Nam ,  Yeon-Hee Hong ,  Sung-Kwang Hong ,  Yang-Su Kang ,  Young-Joo Ha ,  Jeong-Man Rou ,  Suk-Chun Kwack ,  In-Ho Choi ,  Byeong-Woo Kim

IPC分类号： C12M1/34 ,  C12Q1/68 ,  G01N33/48 ,  G01N33/50 ,  G06F19/00

CPC分类号： C12Q1/6876 ,  C12Q1/6837 ,  C12Q2600/124 ,  C12Q2600/158

摘要： The present invention relates to screening of the expression profile of fat specific genes according to the growing stages in swine and a functional cDNA chip using the same and provides expression files of the fat specific genes specifically expressed according to the growing stages in the muscle and fat tissues of swine. Also, the present invention provides a functional cDNA chip for meat quality evaluation and screening of specific genes in swine prepared by integrating only the fat specific genes screened as described above. Therefore, the functional cDNA chip can be used to evaluate of meat quality according to breeds of swine and to bring a high meat quality swine.

摘要翻译： 本发明涉及根据猪的生长期和使用其的功能性cDNA芯片筛选脂肪特异性基因的表达谱，并提供根据肌肉和脂肪中生长阶段特异性表达的脂肪特异性基因的表达文件 猪的组织。 此外，本发明提供了用于通过仅整合如上所述筛选的脂肪特异性基因制备的猪的特定基因的肉质量评价和筛选的功能性cDNA芯片。 因此，功能性cDNA芯片可用于根据猪品种对肉质进行评估，并提供高品质的猪。