公开(公告)号：US08803084B2

公开(公告)日：2014-08-12

申请号：US13726294

申请日：2012-12-24

Applicant: Hitachi High-Technologies Corporation

Inventor： Kazushige Nishimura ,  Yuichiro Hashimoto ,  Masuyuki Sugiyama ,  Masuyoshi Yamada ,  Hidetoshi Morokuma

IPC: H01J49/10

CPC classification number: H01J49/105 ,  H05H1/2406 ,  H05H2001/245 ,  H05H2001/2456

Abstract: A mass spectrometer featured in including an ion source including a first electrode, a second electrode, and a dielectric unit having a sample introducing unit and a sample discharging unit and provided between the first electrode and the second electrode, a power source of ionizing a sample by a discharge generated between the first electrode and the second electrode by applying an alternating current voltage to either one of the first electrode and the second electrode, a mass spectrometry unit of analyzing an ion discharged from the sample discharging unit, and a light irradiating unit of irradiating an area of generating the discharge with light.

Abstract translation: 一种质谱仪，其特征在于包括离子源，所述离子源包括第一电极，第二电极和具有样品引入单元和样品排出单元并且设置在所述第一电极和所述第二电极之间的电介质单元， 通过对第一电极和第二电极中的任一个施加交流电压，通过对第一电极和第二电极之间产生的放电进行分析，分析从取样放出单元排出的离子的质谱分析单元和光照射单元 用光照射产生放电的区域。

公开(公告)号：US11101121B2

公开(公告)日：2021-08-24

申请号：US15568529

申请日：2016-03-30

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Hideki Hasegawa ,  Shun Kumano ,  Yuichiro Hashimoto

IPC: H01J49/00 ,  G01N30/30 ,  G01N30/32 ,  H01J49/04 ,  G01N30/54

Abstract: For increasing a speed of fragmentation of a sample, such as a protein and a peptide, to enhance introduction efficiency into a detector, such as a mass spectrometer, a liquid feeding pump 2, a sample injector 3, and a separation column 6 that are connected via pipes are included, and further, a heating unit 4 for heating a pipe between the sample injector 3 and the separation column 6, and a pressure regulating unit 5 provided between the heating unit 4 and the separation column 6 for regulating the inner pressure of the pipe heated by the heating unit 4, are included.

公开(公告)号：US10551346B2

公开(公告)日：2020-02-04

申请号：US16323168

申请日：2016-08-19

Applicant: Hitachi High-Technologies Corporation

Inventor： Kazushige Nishimura ,  Masuyuki Sugiyama ,  Hideki Hasegawa ,  Yuichiro Hashimoto

IPC: G01N27/62 ,  H01J49/00 ,  H01J49/04 ,  H01J49/06 ,  H01J49/26

Abstract: An ion analysis device includes: an ion source that ionizes an analyte in a liquid sample; an ion guide into which droplets and ions produced in the ion source are introduced, the ion guide having different outlets, one outlet being an ion outlet for the ions and the other outlet being a droplet outlet for the droplets; an ion analysis unit that analyzes ions ejected from the ion outlet; a droplet measurement unit that is placed on an axis of the droplet outlet, and measures the amount of droplets; and an analysis control section that compares the amount of droplets measured at the droplet measurement unit with a threshold.

公开(公告)号：US10204773B2

公开(公告)日：2019-02-12

申请号：US15549228

申请日：2015-02-23

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Masuyuki Sugiyama ,  Hideki Hasegawa ,  Masao Suga ,  Hiroyuki Satake ,  Yuichiro Hashimoto

IPC: H01J49/00 ,  H01J49/06 ,  H01J49/42

Abstract: A first rod electrode set has a first center axis, into which ions and air current are introduced. A second rod electrode set has a second center axis at a distance from the first center axis, from which the ions are discharged. A power supply applies voltages to the first rod electrode set and the second rod electrode set. The first rod electrode set and the second rod electrode set have a region where the sets overlap each other in the longitudinal direction, and form a single multipole ion guide by being combined to each other in the region. Different offset DC voltages are applied to the first rod electrode set and the second rod electrode set, respectively, and a DC potential for moving the ions to the second rod electrode set in the region is formed, the ions having been guided by the first rod electrode set.