公开(公告)号：US09852897B2

公开(公告)日：2017-12-26

申请号：US14442199

申请日：2013-11-07

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Hideki Hasegawa ,  Hiroyuki Satake ,  Masao Suga ,  Yuichiro Hashimoto

IPC: H01J49/10 ,  G01N27/62 ,  H01J49/16

CPC classification number: H01J49/107 ,  G01N27/62 ,  H01J49/165 ,  H01J49/168

Abstract: Provided is an ion source achieving high sensitivity and high robustness while executing a plurality of types of ionization schemes. To this end, a hybrid ion source (1) includes: a chamber (24); a first ion source (2) to spray a sample solution (5) for ionization; a second ion source (3) to ionize droplets and/or a gas component sprayed from the first ion source (2); a first electrode (11) to introduce a first ion (7) generated by the first ion source (2), and a second ion generated by the second ion source (3); and an exhaust pump (27) that generates air flow (26) in a direction from a first space area (23) where the first ion (7) is generated to a second space area (19) in the second ion source (3) where the second ion is generated.

公开(公告)号：US20150001392A1

公开(公告)日：2015-01-01

申请号：US14371043

申请日：2012-12-21

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Hideki Hasegawa ,  Hiroyuki Satake ,  Masao Suga ,  Yuichiro Hashimoto

IPC: H01J49/24 ,  H01J49/06 ,  H01J49/04 ,  H01J49/26

CPC classification number: H01J49/24 ,  H01J49/0404 ,  H01J49/0431 ,  H01J49/062 ,  H01J49/26

Abstract: An object of the present invention is to prevent lowering of introduction efficiency of ions and to reduce labor for a cleaning operation. In order to solve the above problems, the present invention provides a mass spectrometer where ion introduction hole of an electrode is divided into a first region, a second region, and a third region, a central axis direction of the ion introduction hole in both or either one of the first region and the third region is different from a flow direction axis of the ion inside the ion introduction hole in the second region, and axes of the ion introduction hole in the first region and the third region are in an eccentric position relationship.

Abstract translation: 本发明的目的是防止降低离子的引入效率并减少清洗操作的劳动。 为了解决上述问题，本发明提供了一种质谱仪，其中电极的离子引入孔分成第一区域，第二区域和第三区域，离子引入孔的中心轴方向在两者或 第一区域和第三区域中的任一个与第二区域中的离子导入孔内的离子的流动方向轴不同，第一区域和第三区域中的离子导入孔的轴线处于偏心位置 关系。

公开(公告)号：US09892901B2

公开(公告)日：2018-02-13

申请号：US15324092

申请日：2015-06-15

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Hideki Hasegawa ,  Hiroyuki Satake ,  Masao Suga ,  Yuichiro Hashimoto

IPC: H01J49/24 ,  H01J49/34 ,  H01J49/16 ,  H01J49/04

CPC classification number: H01J49/24 ,  G01N27/62 ,  H01J49/0404 ,  H01J49/0422 ,  H01J49/067 ,  H01J49/165 ,  H01J49/34

Abstract: A mass spectrometry device that can perform highly robust, highly sensitive, and low-noise analysis and addresses the problems of preventing reductions in ion transfer efficiency and of suppressing the introduction of noise components from droplets, etc. An ion source generates ions, a vacuum chamber is evacuated by an evacuation means and for analyzing the mass of ions, and an ion introduction electrode introduces ions into the vacuum chamber. The ion introduction electrode has an ion-source-side front-stage pore, a vacuum-chamber-side rear-stage pore, and an intermediate pressure chamber between the front-stage pore and the rear-stage pore, the cross-sectional area of an ion inlet of the intermediate pressure chamber is larger than the cross-sectional area of the front-stage pore, the position of the central axis of the front-stage pore and the position of the central axis of the rear-stage pore are eccentric, and the cross-sectional area of an ion outlet of the intermediate pressure chamber is smaller than the cross-sectional area of the ion inlet.

公开(公告)号：US10424472B2

公开(公告)日：2019-09-24

申请号：US16228982

申请日：2018-12-21

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Masuyuki Sugiyama ,  Hideki Hasegawa ,  Masao Suga ,  Hiroyuki Satake ,  Yuichiro Hashimoto

IPC: H01J49/06 ,  H01J49/42

Abstract: A first rod electrode set has a first center axis, into which ions and air current are introduced. A second rod electrode set has a second center axis at a distance from the first center axis, from which the ions are discharged. A power supply applies voltages to the first rod electrode set and the second rod electrode set. The first rod electrode set and the second rod electrode set have a region where the sets overlap each other in the longitudinal direction, and form a single multipole ion guide by being combined to each other in the region. Different offset DC voltages are applied to the first rod electrode set and the second rod electrode set, respectively, and a DC potential for moving the ions to the second rod electrode set in the region is formed, the ions having been guided by the first rod electrode set.

公开(公告)号：US10036737B2

公开(公告)日：2018-07-31

申请号：US14782424

申请日：2014-04-10

Applicant: Hitachi High-Technologies Corporation

Inventor： Hiroyuki Satake ,  Yuichiro Hashimoto ,  Masao Suga ,  Hideki Hasegawa

IPC: G01N30/72 ,  G01N27/62 ,  H01J49/00

CPC classification number: G01N30/7233 ,  G01N27/624 ,  H01J49/0027 ,  H01J49/004

Abstract: An analysis system is provided with: a storage unit that stores first information associating mass spectrometry result information with an analysis condition concerning ion mobility separation; and a control unit that determines, as a first analysis condition for an ion to be measured, the analysis condition associated with the mass spectrometry result information of the first information corresponding to the mass spectrometry result information of the ion to be measured.

公开(公告)号：US09177775B2

公开(公告)日：2015-11-03

申请号：US14371043

申请日：2012-12-21

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Hideki Hasegawa ,  Hiroyuki Satake ,  Masao Suga ,  Yuichiro Hashimoto

IPC: H01J49/04 ,  H01J49/24 ,  H01J49/06 ,  H01J49/26

CPC classification number: H01J49/24 ,  H01J49/0404 ,  H01J49/0431 ,  H01J49/062 ,  H01J49/26

Abstract: An object of the present invention is to prevent lowering of introduction efficiency of ions and to reduce labor for a cleaning operation. In order to solve the above problems, the present invention provides a mass spectrometer where ion introduction hole of an electrode is divided into a first region, a second region, and a third region, a central axis direction of the ion introduction hole in both or either one of the first region and the third region is different from a flow direction axis of the ion inside the ion introduction hole in the second region, and axes of the ion introduction hole in the first region and the third region are in an eccentric position relationship.

Abstract translation: 本发明的目的是防止降低离子的引入效率并减少清洗操作的劳动。 为了解决上述问题，本发明提供了一种质谱仪，其中电极的离子引入孔分成第一区域，第二区域和第三区域，离子引入孔的中心轴方向在两者或 第一区域和第三区域中的任一个与第二区域中的离子导入孔内的离子的流动方向轴不同，第一区域和第三区域中的离子导入孔的轴线处于偏心位置 关系。

公开(公告)号：US10139369B2

公开(公告)日：2018-11-27

申请号：US15534607

申请日：2014-12-24

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Hiroyuki Satake ,  Hideki Hasegawa ,  Masao Suga ,  Yuichiro Hashimoto

IPC: G01N27/62 ,  H01J49/04

Abstract: A mass spectrometer device comprising an ion mobility separation device and a mass spectrometer that are coupled together. In order to achieve high efficiency, high throughput, and high sensitivity, the mass spectrometer is provided with: a first flow passageway 24 through which ions from an ion source 1 are introduced into the mass spectrometer 11 by passing through an ion mobility separation unit 2; a second flow passageway 21 through which the ions from the ion source are introduced into the mass spectrometer without passing through the ion mobility separation unit; and a switch means, such as shield units 4, 5, for switching between the first flow passageway 24 and the second flow passageway 21.

公开(公告)号：US10204773B2

公开(公告)日：2019-02-12

申请号：US15549228

申请日：2015-02-23

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Masuyuki Sugiyama ,  Hideki Hasegawa ,  Masao Suga ,  Hiroyuki Satake ,  Yuichiro Hashimoto

IPC: H01J49/00 ,  H01J49/06 ,  H01J49/42

Abstract: A first rod electrode set has a first center axis, into which ions and air current are introduced. A second rod electrode set has a second center axis at a distance from the first center axis, from which the ions are discharged. A power supply applies voltages to the first rod electrode set and the second rod electrode set. The first rod electrode set and the second rod electrode set have a region where the sets overlap each other in the longitudinal direction, and form a single multipole ion guide by being combined to each other in the region. Different offset DC voltages are applied to the first rod electrode set and the second rod electrode set, respectively, and a DC potential for moving the ions to the second rod electrode set in the region is formed, the ions having been guided by the first rod electrode set.