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公开(公告)号：US08476222B2
公开(公告)日：2013-07-02
申请号：US12417307
申请日：2009-04-02
申请人： Gerhard Seibert , László Vértesy , Joachim Wink , Irvin Winkler , Mark Broenstrup , Holger Hoffmann , Hans Guehring , Luigi Toti , Roderich Süssmuth , George M. Sheldrick , Kathrin Meindl
发明人： Gerhard Seibert , László Vértesy , Joachim Wink , Irvin Winkler , Mark Broenstrup , Holger Hoffmann , Hans Guehring , Luigi Toti , Roderich Süssmuth , George M. Sheldrick , Kathrin Meindl
摘要： The disclosure relates to a compound of the formula (I) wherein R1 is H, C(O)—(C1-C6)alkyl or C(O)—O—(C1-C6)alkyl; R2 is OH, NH2, NH—(C1-C6)alkyl, NH—(C1-C4)alkylene-phenyl or NH—(C1-C4)alkylene-pyridyl; R3 and R4 are independently of each other H or OH, or R3 and R4 together are ═O; and m and n are independently of one another 0, 1 or 2; in any stereochemical form, or a mixture of any stereochemical forms in any ratio, or a physiologically acceptable salt thereof, obtainable from Actinomadura namibiensis (DSM 6313), and its use for the treatment of bacterial infections, viral infections and/or pain, and pharmaceutical composition comprising it.
摘要翻译： 本发明涉及式（I）化合物，其中R 1是H，C（O） - （C 1 -C 6）烷基或C（O）-O-（C 1 -C 6）烷基; R2是OH，NH2，NH-（C1-C6）烷基，NH-（C1-C4）亚烷基 - 苯基或NH-（C1-C4）亚烷基 - 吡啶基; R3和R4彼此独立地为H或OH，或R3和R4一起为= O; m和n彼此独立地为0,1或2; 任何立体化学形式，或任何比例的任何立体化学形式的混合物，或其生理学上可接受的盐，可从放线杆菌素（DSM 6313）获得，以及其用于治疗细菌感染，病毒感染和/或疼痛的用途，以及 包含它的药物组合物。
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公开(公告)号：US20090298904A1
公开(公告)日：2009-12-03
申请号：US12417307
申请日：2009-04-02
申请人： Gerhard Seibert , László Vértesy , Joachim Wink , Irvin Winkler , Mark Broenstrup , Holger Hoffmann , Hans Guehring , Luigi Toti , Roderich Süssmuth , George M. Sheldrick , Kathrin Meindl
发明人： Gerhard Seibert , László Vértesy , Joachim Wink , Irvin Winkler , Mark Broenstrup , Holger Hoffmann , Hans Guehring , Luigi Toti , Roderich Süssmuth , George M. Sheldrick , Kathrin Meindl
IPC分类号： A61K31/40 , C07D513/18 , C12P17/18
摘要： The disclosure relates to a compound of the formula (I) wherein m and n are independently of one another 0, 1 or 2, obtainable from Actinomadura namibiensis (DSM 6313), its use for the treatment of bacterial infections, viral infections and/or pain, and pharmaceutical composition comprising it.
摘要翻译： 本公开涉及式（I）的化合物，其中m和n彼此独立地为0,1或2，可从放线菌素（DSM 6313）获得，其用于治疗细菌感染，病毒感染和/或 疼痛和包含它的药物组合物。
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公开(公告)号：US07534591B2
公开(公告)日：2009-05-19
申请号：US11555804
申请日：2006-11-02
CPC分类号： C12R1/01 , C07D223/12 , C12P17/10
摘要： The present invention relates to bengamide derivatives which are formed, during fermentation, by the microorganism Myxococcus virescens ST200611 (DSM 15898), to their use for treating cancer diseases, to pharmaceuticals which comprise bengamide derivatives, to a process for preparing bengamides of the formula (V) and to the microorganism Myxococcus virescens ST200611 (DSM 15898).
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公开(公告)号：US5688589A
公开(公告)日：1997-11-18
申请号：US604511
申请日：1996-02-21
申请人： Wolfgang Schacht , Robert Gereke , Frank Henke , Holger Hoffmann
发明人： Wolfgang Schacht , Robert Gereke , Frank Henke , Holger Hoffmann
IPC分类号： B60J10/35 , B60R13/02 , C09J7/02 , C09J11/04 , C09J201/00
CPC分类号： B60R13/02 , B60J10/35 , C09J7/0246 , C09J7/0271 , Y10T428/249983 , Y10T428/2848
摘要： Pressure-sensitive self-adhesive tape comprising a backing made of general purpose rubber, the backing being coated on both sides with pressure-sensitive adhesive compositions.
摘要翻译： 包括由通用橡胶制成的背衬的压敏自粘胶带，背面用压敏粘合剂组合物涂覆在两面上。
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